This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, microscopic characteristics of the mechanisms by which chemicals can produce liver injury and experimental models useful for the study of liver dysfunction.

Growing public discontent with the performance and quality of many contemporary democracies makes them vulnerable to popular pressures to profoundly transform or replace their constitutions. However, there is little systematic academic discussion on the legal and political challenges that these events pose to democratic principles and practices. This book, a collaborative effort by legal scholars and political scientists, analyzes these challenges from an interdisciplinary and comparative perspective. It fills a theoretical vacuum by examining the possibility that constitutions might be replaced within a democratic regime, while exploring the conditions under which these processes are more compatible or less compatible with democratic principles. It also calls attention to the real-world political importance of the phenomenon, because recent episodes of constitutional redrafting in countries including Kenya, Poland, Venezuela and Hungary suggest that some aspects of these processes may be associated with either the improvement or the gradual erosion of democracy.

Growing public discontent with the performance and quality of many contemporary democracies makes them vulnerable to popular pressures to profoundly transform or replace their constitutions. However, there is little systematic academic discussion on the legal and political challenges that these events pose to democratic principles and practices. This book, a collaborative effort by legal scholars and political scientists, analyzes these challenges from an interdisciplinary and comparative perspective. It fills a theoretical vacuum by examining the possibility that constitutions might be replaced within a democratic regime, while exploring the conditions under which these processes are more compatible or less compatible with democratic principles. It also calls attention to the real-world political importance of the phenomenon, because recent episodes of constitutional redrafting in countries including Kenya, Poland, Venezuela and Hungary suggest that some aspects of these processes may be associated with either the improvement or the gradual erosion of democracy.

This book provides the first systematic explanation of the origins of constitutional designs from an analytical, historical, and comparative perspective. Based on a comprehensive analysis of constitutional change in Latin America from 1900 to 2008 and four detailed case studies, Gabriel Negretto shows that the main determinants of constitutional choice are the past performance of constitutions in providing effective and legitimate instruments of government and the strategic interests of the actors who have influence over institutional selection. The book explains how governance problems shape the general guidelines for reform, while strategic calculations and power resources affect the selection of specific alternatives of design. It also emphasizes the importance of the events that trigger reform and the designers' level of electoral uncertainty for understanding the relative impact of short-term partisan interests on constitution writing. Negretto's study challenges predominant theories of institutional choice, and paves the way for the development of a new research agenda on institutional change.

Folklorist Arnold van Gennep's masterwork, The Rites of Passage, has been a staple of anthropological education for more than a century. First published in French in 1909, and translated into English by the University of Chicago Press in 1960, this landmark book explores how the life of an individual in any society can be understood as a succession of stages: birth, puberty, marriage, parenthood, advancement to elderhood, and, finally, death. Van Gennep's command of the ethnographic record enabled him to discern crosscultural patterns in rituals of separation, transition, and incorporation. With compelling precision, he elaborated the terms that would both define twentieth-century ritual theory and become a part of our everyday lexicon. This new edition of his work demonstrates how we can still make use of its enduring critical tools to understand our own social, religious, and political worlds. Featuring an introduction by Pulitzer Prize-winning anthropologist and historian David I. Kertzer, this edition reminds readers just how startlingly insightful The Rites of Passage remains a century after its initial publication.

Negretto provides the first systematic explanation of the origins of constitutional designs from an analytical, historical and comparative perspective. Based on analysis of constitutional change in Latin America from 1900 to 2008 and four detailed case studies, Negretto shows the main determinants of constitutional choice are the past performance of constitutions in providing effective and legitimate instruments of government and the strategic interests of the actors who have influence over institutional selection. The book explains how governance problems shape the general guidelines for reform, while strategic calculations and power resources affect the selection of specific alternatives of design. It emphasizes the importance of events that trigger reform and the designers' level of electoral uncertainty for understanding the relative impact of short-term partisan interests on constitution writing. Negretto's study challenges predominant theories of institutional choice and paves the way for the development of a new research agenda on institutional change.

This series gathers and presents original research in the study of the Presidency of the United States. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the issuance, modification and revocation of executive orders; the debate over selected presidential assistants and advisors; nominations to cabinet positions during inter-term transitions since 1984; financial assets and conflict of interest regulations in the executive branch; and an analysis of young-adult voting for presidential elections from 1964 to 2012.

Don't say in the years to come that you would have lived your life differently if only you had heard this story. You've heard it now."" - Thomas King, in this volumeRead, Listen, Tell brings together an extraordinary range of Indigenous stories from across Turtle Island (North America). From short fiction to as-told-to narratives, from illustrated stories to personal essays, these stories celebrate the strength of heritage and the liveliness of innovation. Ranging in tone from humorous to defiant to triumphant, the stories explore core concepts in Indigenous literary expression, such as the relations between land, language, and community, the variety of narrative forms, and the continuities between oral and written forms of expression. Rich in insight and bold in execution, the stories proclaim the diversity, vitality, and depth of Indigenous writing. Building on two decades of scholarly work to centre Indigenous knowledges and perspectives, the book transforms literary method while respecting and honouring Indigenous histories and peoples of these lands. It includes stories by acclaimed writerslike Thomas King, Sherman Alexie, Paula Gunn Allen, and Eden Robinson, a new generation of emergent writers, and writers and storytellers who have often been excluded from the canon, such as French- and Spanish-language Indigenous authors, Indigenous authors from Mexico, Chicana/o authors, Indigenous-language authors, works in translation, and ""lost"" or underappreciated texts. In a place and time when Indigenous people often have to contend with representations that marginalize or devalue their intellectual and cultural heritage, this collection is a testament to Indigenous resilience and creativity. It shows that the ways in which we read, listen, and tell play key roles in how we establish relationships with one another, and how we might share knowledges across cultures, languages, and social spaces.

This series gathers and presents original research in the study of the Presidency of the United States. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the Presidential inauguration; joint Congressional Committee on inaugural ceremonies; inauguration security; the President's budget; gifts to the President of the United States; the 2013 cybersecurity executive order; national security and emergency preparedness communications; and executive order 13438.

This series gathers and presents original research in the study of the Presidency of the United States. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the history, law, practice and recent developments relating to presidential claims of executive privilege; classified information policy and executive order 13526; national security considerations and options during the 2012-2013 presidential election period; and provisions and funding in the Presidential Transaction Act.

"Saving a White Knight" is an erotic story dealing with the effects of university social politics on men in the United States. University Professor Russell Patton hates himself, and he does not even know it. Known to others as a white knight, Russell, suffering from stress and frequent headaches, lives his life in a shroud of political correctness, unable to see beyond the boundaries. Sometimes, the headaches become too painful and the stress too intense, and Russell sneaks away guiltily for a 'happy ending' massage on the other side of town. A series of events, beginning with a false discrimination complaint, force Russell to examine his life and conditioned beliefs. The novella serves as an indictment of political correctness, conformity and social culture on United States university campuses, but it is also romantic and erotic with plenty of graphic sex scenes. "Saving a White Knight" is ultimately a coming-of-age story for men.

This series gathers and presents original research in the study of the Presidency of the United States. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the constitutional and institutional implications of presidential signing statements; an overview of the executive budget process; submission of the President's budget in transition years; how the electoral college works in contemporary presidential elections; the counting of electoral votes and an overview of procedures at the joint session, including objections by members of Congress; and a discussion of presidential appointee positions requiring Senate confirmation and committees handling nominations.

This series gathers and presents original research in the study of the Presidency of the United States. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include contemporary developments in presidential elections; the presidential nominating process and the national party conventions for 2012; midnight rule-making; nominations to U.S. circuit and district courts by President Obama during the 111th and 112th congresses; and regular vetoes and pocket vetoes.