Using Documents presents an interdisciplinary discussion of human communication by means of documents, e.g., letters. Cultural scientists, together with researchers from media science and media engineering, analyze questions of document modeling, including a document's contexts of use, on the basis of cultural theory. The research also concerns the debate on the material turn in the fields of cultural studies and media studies. Looking back on existing work, texts on written communication by the philosopher and sociologist Georg Simmel and by an interdisciplinary French group of authors under the pseudonym Roger T. Pedauque are taken as a starting point and presented afresh. A look ahead to the future is also attempted. Whereas the modeling (including technical modeling) of documents has to date largely been limited to the description of output forms and specific content, the foundations are laid here for including documents' contexts of use in models that are grounded in cultural theory.

This book presents a new basis for the empirical analysis of film. Starting from an established body of work in film theory, the authors show how a close incorporation of the current state of the art in multimodal theory, including accounts of the syntagmatic and paradigmatic axes of organisation, discourse semantics and advanced layout structure, provides a methodology by which concrete details of film sequences drive mechanisms for constructing filmic discourse structures. The book introduces the necessary background, the open questions raised, and the method by which analysis can proceed step-by-step with extensive examples drawn from a broad range of films. The book aims to provide an analytic tool set that will enable the reader to approach the study of film organisation with new levels of detail, probing deeply into the fundamental question of film as to just how it is that films reliably communicate meaning.

This book presents a new basis for the empirical analysis of film. Starting from an established body of work in film theory, the authors show how a close incorporation of the current state of the art in multimodal theory-including accounts of the syntagmatic and paradigmatic axes of organisation, discourse semantics and advanced 'layout structure'-builds a methodology by which concrete details of film sequences drive mechanisms for constructing filmic discourse structures. The book introduces the necessary background, the open questions raised, and the method by which analysis can proceed step-by-step. Extensive examples are given from a broad range of films. With this new analytic tool set, the reader will approach the study of film organisation with new levels of detail and probe more deeply into the fundamental question of the discipline: just how is it that films reliably communicate meaning?

Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are dex scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.