Evidence-based medicine, the "gold standard" of medical decision making, is increasingly unpopular with clinicians. They are right to have reservations. EBM breaks the laws of so many disciplines that it cannot be considered scientific or even rational. Decision science and cybernetics show the disturbing consequences of such flaws. EBM fosters marginally effective treatments, based on population averages rather than individual need. Its mega-trials are theoretically incapable of finding the causes of disease, yet swallow up research funds. Ultimately, EBM cannot avoid risking patients' health. It is time for medical practitioners to discard EBM's tarnished gold standard, reclaim their clinical autonomy, and provide individualised treatments to patients. This book explains why and how.