Introducing readers to the latest research applications, the new Fifth Edition of the bestselling Physical Chemistry: Principles and Applications in Biological Sciences with MasteringChemistry(r) puts the study of physical chemistry in context. Clear writing and the ideal level of mathematics combine for an engaging overview of the principles and applications of contemporary physical chemistry as used to solve problems in biology, biochemistry, and medicine. The addition of MasteringChemistry(r) to the program puts a host of effective study tools at readers' fingertips.

Nucleic Acids presents an up-to-date and comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function. With a targeted audience of 1) molecular biologists, 2) physical biochemists, and 3) physical chemists, the book has been carefully organized to reach three different audiences while requiring only introductory physical chemistry and molecular biology as prerequisites. Nucleic Acids will serve as a textbook in physical biochemistry and biophysical chemistry classes, as well as a supplemental text in courses on nucleic acid biochemistry or molecular biology, and as a personal reference for students and researchers in these fields. Key Features Organized according to a systematic consideration of techniques used in the study of nucleic acid structure and properties. Key topics - such as protein-DNA and protein-drug complexes, conformational transitions, characterization of nucleic acids by gel and solution techniques, and behavior of supercoiled DNA - are covered in great detail as veritable mini-monographs. Heavily illustrated with diagrams, graphs, and molecular structures, including nearly 2 dozen color figures. Includes numerous figures, tables and an extensive bibliography to facilitate use as a reference volume.