Zooarchaeology in Practice unites depth of treatment with broad topical coverage to advance methodological discussion and development in archaeofaunal analysis. Through case studies, historical accounts, and technical reviews authored by leading figures in the field, the volume examines how zooarchaeological data and interpretation are shaped by its methods of practice and explores the impact of these effects at varying levels of investigation. Contributing authors draw on geographically and taxonomically diverse datasets, providing instructive approaches to problems in traditional and emerging areas of methodological concern. Readers, from specialists to students, will gain an extensive, sophisticated look at important disciplinary issues that are sure to provoke critical reflection on the nature and importance of sound methodology. With implications for how archaeologists reconstruct human behavior and paleoecology, and broader relevance to fields such as paleontology and conservation biology, Zooarchaeology in Practice makes an enduring contribution to the methodological advancement of the discipline.

Diabetes mellitus represents one of the most frequent and serious clinical syn dromes in contemporary medicine. Since the end of the nineteenth century, the endocrine pancreas has been implicated in the pathogenesis of this disease. Several pathologists of the twentieth century detected various lesions and mor phologic alterations in the pancreatic islets of diabetic patients, but the patho physiologic basis of their findings remained long obscure. The systematic mi croscopic work of WILLY GEPTS clarified the views and related the variety in histopathology to differences in origin, duration and clinical expression of the disease. Over the past two decades, the concept of a multifactorial origin of diabetes has become widely accepted. Various agents and mechanisms have been identified which can lead to a quantitative or qualitative deficit in pancre atic B-cells. The purpose of this book is to bring an update on the many path ways which may induce an absolute or relative insufficiency in insulin release and hence a diabetic state. Rather than bringing a complete account on all re search relevant to the understanding of the pathology of the diabetic pancreas, the authors of the various chapters of this volume have focussed on selected processes which can impair B-cell function, survival or regeneration.

Glucagon III complements "Glucagon I" and "II" published in 1983 in this series as "Vols. 66/I" and "II." These three volumes truly represent a "glucagon encyclopedia" and as such have no competitors in the scientific literature worldwide. In this volume, the most recent data on glucagon molecular biology are reviewed together with clinically relevant information on the role of glucagon in the pathophysiology of diabetes, the place of glucagon in medical imaging or in emergency medicine. Chapters are devoted to newly identified members of the glucagon family such as glucagon-like peptide-1 (GLP-1) and oxyntomodulin. Glucagon III is a comprehensive review of all information published on this important hormone since 1983 and is "the" reference book on the subject.

His scientific contributions are regarded as classics: the studies about the insulin effect on adipose tissue (together with George F. Cahill Jr. ), his work on the biosyn- thesis and secretion of insulin (together with Lelio Orci and Claes W ollheim) and his studies on various spontaneous and induced diabetes syndromes in rodents (together with Bernard Jeanrenaud and Eleazar Shafrir). Albert Renold will be remembered for a long time by all who knew him for his achievements, for his kindness and his humanity. We dedicate the Proceedings of this symposium to his memory. Werner Creutzfeldt Pierre Lefebvre G6ttingen Liege History and Philosophy of Bayer Pharmaceutical Research W. -D. Busse Fachbereich Forschung Pharma, Bayer AG, D-5600 Wuppertal, FRG Research has a long tradition at Bayer. This year, 1988, marks 100 years of our pharmaceutical activities. In 1888 the first Bayer drug - phenacetin, an antipyreti- was synthesized, starting from a by-product of dye manufacture. This finding led to the establishment of a Pharmaceutical Department within Friedrich Bayer and Co. in Elberfeld, with all its associated facilities (Fig. 1). The beginning of the company itself, however, dates back to 1863. In that year, Friedrich Bayer started the produc- tion of aniline dyestuffs in his private house in Barmen-Rittershausen. During the 125 years of the company's life and the 100 years of pharmaceuticals, many developments and products have been discovered by Bayer researchers and launched by Bayer.

Strategy is the art of thinking about war before it occurs. Noting that space already plays a role in all of today s wars, Space Strategy studies how conflicts are extending into this new domain. The book defines extra-atmospheric space and focuses on its varying features and constraints. By exploring the opportunities for action provided by different strategic positions, the book analyzes the most plausible combat scenarios from, against and within space. It explains the concepts of militarization, weaponization and martialization of space and shows how space systems constitute an essential component of information literacy the key to power in the 21st Century. Space Strategy then demonstrates why our society, having become space-dependent, must take appropriate measures to develop its spatioresilience. Finally, the author summarizes his reflections in the form of a mnemonic listing twelve principles of space strategy. Completed by educational appendices and a glossary containing one thousand entries, Space Strategy meets the needs of students, researchers or any other reader curious about expanding their knowledge of strategy.

This is a reproduction of a book published before 1923. This book may have occasional imperfectionssuch as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed worksworldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.++++The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Portraits D'hommes Et De Femmes Illustres Fulvio Orsini, J. Le Febvre, Charles-C℗esar Baudelot de Dairval Cott, 1710