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Significant progress has been made in recent years in understanding
the origins of cutaneous maligant melanoma. Knowledge of the
relationship between solar radiation and melanoma has changed and
it now appears that both the character and timing of exposure may
be more important than total cumulative dose in accounting for
risk. The melanoma-sunlight model may prove an instructive
heuristic exercise for environmental epidemiology, as we currently
tend to restrict ourselves to a search for uniform total
dose--response relationships between cancers and suspected
environmental carcinogens. The study of the relationship between
acquired melanocytic nevi and melanoma has led to useful new
information about predictors of melanoma risk, and in addition has
opened new perspectives on the development of nevi in children.
Definition of the factors for nevus development in children may
lead to the possibility of primary prevention programs for melanoma
in younger generations of children. Recent new evidence suggests
that certain occupational groups may be at elevated risk of
melanoma. A great deal of work is going into the study of ways of
screening high risk populations in order to detect melanoma at its
earliest stages when current treatment protocols are most
effective. The visibility of lesions on the skin challenges
classical definitions of early detection and screening in
epidemiology.
Our series Cancer Prevention - Cancer Control continues to address
the causes and prevention of cancer. In this volume, Hill, Elwood,
and English bring together a rich resource summarizing the state of
science underpinning the primary prevention of skin cancer. While
skin cancer causes an increasing burden, particularly in
populations of European origin, our understanding of the role of
sun exposure together with the genetic components of skin cancer
continues to grow. Given the emphasis on evidence-based medicine
and public health prevention efforts, it is noteworthy that,
although we can all access the same evidence base, countries around
the world have had remarkably different responses to the
application of this knowledge to prevent skin cancer. The
outstanding contribution of the Australian public health community
to the scientific understanding of skin cancer etiology and the
translation of this knowledge into national prevention efforts
uniquely positions the editors to compile this volume focused on
the primary prevention of skin cancer. In so doing they draw on an
international team of authors to present a "state of the science"
summary of skin cancer prevention and to identify those areas where
uncertainty remains. To achieve successful prevention of cancer we
must translate our scientific knowledge base into effective
prevention programs. This book offers the reader keen insights into
the depth of our understanding of etiologic pathways for skin
cancer. This etiologic science base is complemented by rigorous
prevention science placing emphasis on the social context for
effective and sustained prevention efforts.
Our series Cancer Prevention - Cancer Control continues to address
the causes and prevention of cancer. In this volume, Hill, Elwood,
and English bring together a rich resource summarizing the state of
science underpinning the primary prevention of skin cancer. While
skin cancer causes an increasing burden, particularly in
populations of European origin, our understanding of the role of
sun exposure together with the genetic components of skin cancer
continues to grow. Given the emphasis on evidence-based medicine
and public health prevention efforts, it is noteworthy that,
although we can all access the same evidence base, countries around
the world have had remarkably different responses to the
application of this knowledge to prevent skin cancer. The
outstanding contribution of the Australian public health community
to the scientific understanding of skin cancer etiology and the
translation of this knowledge into national prevention efforts
uniquely positions the editors to compile this volume focused on
the primary prevention of skin cancer. In so doing they draw on an
international team of authors to present a "state of the science"
summary of skin cancer prevention and to identify those areas where
uncertainty remains. To achieve successful prevention of cancer we
must translate our scientific knowledge base into effective
prevention programs. This book offers the reader keen insights into
the depth of our understanding of etiologic pathways for skin
cancer. This etiologic science base is complemented by rigorous
prevention science placing emphasis on the social context for
effective and sustained prevention efforts.
Significant progress has been made in recent years in understanding
the origins of cutaneous maligant melanoma. Knowledge of the
relationship between solar radiation and melanoma has changed and
it now appears that both the character and timing of exposure may
be more important than total cumulative dose in accounting for
risk. The melanoma-sunlight model may prove an instructive
heuristic exercise for environmental epidemiology, as we currently
tend to restrict ourselves to a search for uniform total
dose--response relationships between cancers and suspected
environmental carcinogens. The study of the relationship between
acquired melanocytic nevi and melanoma has led to useful new
information about predictors of melanoma risk, and in addition has
opened new perspectives on the development of nevi in children.
Definition of the factors for nevus development in children may
lead to the possibility of primary prevention programs for melanoma
in younger generations of children. Recent new evidence suggests
that certain occupational groups may be at elevated risk of
melanoma. A great deal of work is going into the study of ways of
screening high risk populations in order to detect melanoma at its
earliest stages when current treatment protocols are most
effective. The visibility of lesions on the skin challenges
classical definitions of early detection and screening in
epidemiology.
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