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Two thousand years ago the Roman architect Marcus Vitruvius Pollio wrote the ten books on architecture establishing the concept of the pattern book offering design principles and solutions that is still referred to in every architect's education. A Green Vitruvius is intended as a green pattern book for today. Now fully updated, this well established textbook provides advice suitable for undergraduate and post graduate students on the integration of sustainable practice into the design and construction process, the issues to be considered, the strategies to be adopted, the elements of green design and design evaluation within the process. Classic design elegance is found in the holistic clear solution.
A comprehensive guide to using the Internet for research into all aspects of herbal medicine!This valuable and timely book will help you navigate the sea of information about herbs and herbal remedies on the Internet. In recent years, alternative medicine has come to the forefront of American culture. As editor David J. Owen points out, "It sometimes seems that not a day goes by without the appearance of another newspaper article or television news item about St. John's wort or Ginkgo biloba. Once confined largely to health food stores, herbal preparations are now prominently displayed on the shelves of modern pharmacies and can be readily purchased via the Internet. They are now widely used to treat a variety of conditions, from depression to sexual dysfunction." Today, a great deal of the most reliable information about herbal medicine is available only in scattered sources like trade journals, pamphlets, conference proceedings, and market research reports. Many of these are available online if you know how to find them. The Herbal Internet Companion: Herbs and Herbal Medicine Online will show you how to find the information you need! This book groups the Web sites and other Internet sources it lists based on the type of information you'll find there, providing you with ways to quickly access information about: criteria for assessing the quality of health information on the Internet consumer/patient needs and frequently asked questions mailing lists, chat rooms, and newsgroups providing herbal information laws, standards, and regulations associations and organizations dealing with herbal medicine consumer protection, health fraud, and quackery clinical trials and evidence about specific products Internet resources in specialized health areas such as cancer and AIDS side effects, adverse reactions, and drug interactions online indexes and databases such as MEDLINE . . . and much more! Complete with easy-to-read tables and charts as well as a glossary of terms you'll encounter on these Web sites, The Herbal Internet Companion: Herbs and Herbal Medicine Online is the resource that puts the power of the Internet in your hands!
Two thousand years ago the Roman architect Marcus Vitruvius Pollio wrote the ten books on architecture establishing the concept of the pattern book offering design principles and solutions that is still referred to in every architect's education. A Green Vitruvius is intended as a green pattern book for today. Now fully updated, this well established textbook provides advice suitable for undergraduate and post graduate students on the integration of sustainable practice into the design and construction process, the issues to be considered, the strategies to be adopted, the elements of green design and design evaluation within the process. Classic design elegance is found in the holistic clear solution.
This updated and expanded volume reflects the current state of the structural protein field with improved and refined protocols that have been applied to particularly challenging proteins. Beginning with a section on structural bioinformatics, the book continues with sections covering the challenge of producing high quality samples for structural studies, particularly mammalian membrane proteins and protein complexes, as well as protocols for structure determination, including the use of electrons in structural biology and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Structural Proteomics: High-Throughput Methods, Third Edition will aid researchers in expanding our knowledge of this vital and expansive area of protein science. Chapter 9 is available open access under a CC BY 4.0 license.
The next best thing to knowing something is knowing where to find it. Samuel Johnson The Internet Guide to Herbal Remedies helps you find reliable online resources for the information you need about herbs used to treat a variety of medical conditions, including cancer, heart disease, depression, and AIDS. This easy-to-use consumer guide will help you steer clear of misleadingand potentially harmfulinformation that often amounts to nothing more than a thinly veiled product advertisement, as you search for the accurate and up-to-date news, facts, and advice that are out thereif you know where to look. Author David J. Owen, whose previous book, The Herbal Internet Companion: Herbs and Herbal Medicine Online (Haworth) won the 2002 International Herb Association Book Award, guides you through Web sites, mailing lists, listservs, newsgroups, and databases to uncover safe and sound health information that's aimed at specific conditions and specific populations; there's even a chapter on herbs for pets! You'll find the information you need on the safety and effectiveness of herbal remedies, current laws and regulations governing their use, and the basics of botany, including how herbs are named and what parts of the plants are used. Internet Guide to Herbal Remedies provides the information you need on: decoding herbal product labels general and CAM Web sites PubMed (MEDLINE) Google versus PubMed Web sites that discuss side effects and herb-drug interactions consumer awareness Web sites Web sites for specific diseases and conditions Web sites for specific populations Web addresses, browsers, and navigating Web sites and much more! Internet Guide to Herbal Remedies also includes helpful tables, figures, and screen captures from Web sites. This book is essential for anyone looking for safe and reliable information online.
Since the 1960s, the occult in film and television has responded to and reflected society's crises surrounding gender and sexuality. In Desire After Dark, Andrew J. Owens explores media where figures such as vampires and witches make use of their supernatural knowledge in order to queer what otherwise appears to be a normative world. Beginning with the global sexual revolutions of the '60s and moving decade by decade through "Euro-sleaze" cinema and theatrical hardcore pornography, the HIV/AIDS crisis, the popularity of New Age religions and witchcraft, and finally the increasingly explicit sexualization of American cable television, Owens contends that occult media has risen to prominence during the past 60 years as a way of exposing and working through cultural crises about queerness. Through the use of historiography and textual analyses of media from Bewitched to The Hunger, Owens reveals that the various players in occult media have always been well aware that non-normative sexuality constitutes the heart of horror's enduring appeal. By investigating vampirism, witchcraft, and other manifestations of the supernatural in media, Desire After Dark confirms how the queer has been integral to the evolution of the horror genre and its persistent popularity as both a subcultural and mainstream media form.
This updated and expanded volume reflects the current state of the structural protein field with improved and refined protocols that have been applied to particularly challenging proteins, notably integral membrane proteins and multi-protein complexes. Structural Proteomics: High-Throughput Methods, Second Edition begins by exploring the resources available for curation, annotation, and structure prediction in silico, and continues with methods for sample preparation of both proteins and crystals, as well as structural characterization techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and up-to-date, Structural Proteomics: High-Throughput Methods, Second Edition will aid researchers in expanding our knowledge of this vital and expansive area of protein science.
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
Silicone Surface Science offers a survey of the major topics concerning the properties and behavior of silicone surfaces. It covers all main aspects of the subject, including: polydimethylsiloxane, spread monolayers, self-assembled monolayers, hydrophobicity and super-hydrophobicity, coupling agents, surfactants, fluorosilicones, surface treatments and surface analysis. This book brings together the field's leading experts who investigated both fundamental and applied aspects of silicone surface science and technology, and introduces the reader to the origins and historical development of silicone surfaces as well as to their most significant current key features. Silicone Surface Science is an invaluable guide and indispensable reference source for all those interested in this important area of polymer and materials science and technology, from graduate students to experienced scientists alike.
In The New Superconductors, Frank J. Owens and Charles P. Poole, Jr., offer a descriptive, non-mathematical presentation of the latest superconductors and their properties for the non-specialist. Highlights of this up-to-date text include chapters on superfluidity, the latest copper oxide types, fullerenes, and prospects for future research. The book also features many examples of commercial applications; an extensive glossary that defines superconductivity terms in clear language; and a supplementary list of readings for the interested lay reader.
In 1987 a major breakthrough occurred in materials science. A new family of materials was discovered that became superconducting above the temperature at which nitrogen gas liquifies, namely, 77 K or -196 DegreesC. Within months of the discovery, a wide variety of experimental techniques were brought to bear in order to measure the properties of these materials and to gain an understanding of why they superconduct at such high temperatures. Among the techniques used were electromagnetic absorption in both the normal and the superconducting states. The measurements enabled the determination of a wide variety of properties, and in some instances led to the observation of new effects not seen by other measu- ments, such as the existence of weak-link microwave absorption at low dc magnetic fields. The number of different properties and the degree of detail that can be obtained from magnetic field- and temperature-dependent studies of electromagnetic abso- tion are not widely appreciated. For example, these measurements can provide information on the band gap, critical fields, the H-T irreversibility line, the amount of trapped flux, and even information about the symmetry of the wave function of the Cooper pairs. It is possible to use low dc magnetic field-induced absorption of microwaves with derivative detection to verify the presence of superconductivity in a matter of minutes, and the measurements are often more straightforward than others. For example, they do not require the physical contact with the sample that is necessary when using four-probe resistivity to detect superconductivity.
"Silicone Surface Science" offers a survey of the major topics concerning the properties and behavior of silicone surfaces. It covers all main aspects of the subject, including: polydimethylsiloxane, spread monolayers, self-assembled monolayers, hydrophobicity and super-hydrophobicity, coupling agents, surfactants, fluorosilicones, surface treatments and surface analysis. This book brings together the field's leading experts who investigated both fundamental and applied aspects of silicone surface science and technology, and introduces the reader to the origins and historical development of silicone surfaces as well as to their most significant current key features. "Silicone Surface Science" is an invaluable guide and indispensable reference source for all those interested in this important area of polymer and materials science and technology, from graduate students to experienced scientists alike."
Polyvinyl chloride has played a key role in the development of the plastics industry over the past 40 years and continues to be a polymer of major importance. The reasons for its enormous versatility and range of application derive from a combination of the basic structure which gives rise to a relatively tough and rigid material and its ability to accept a range of plasticisers and other additives which can modify its physical characteristics to produce a range of flexible products. Two major problems, however, have tested the skill and ingenuity of PVC technologists since earliest times. One is the thermal instability of the material at the temperatures required for melt processing and fabrication, and the second is the photochemical instability which until recently has limited the potentially large range of outdoor applications. Both problems have been handled in a commercially satisfactory way by the gradual development of a range of stabilisers, lubricants and other processing aids and the high quality material which has resulted has led to massive utilisation of PVC by industry. Totally adequate stabilisation requires a detailed understanding of the mechanisms by which degradation processes are initiated and propagated. Although great advances have been made in this respect in recent years the problem remains incompletely understood. This book presents an account of the present position and the problems which remain to be solved.
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
Children born during the post-WWII era of peace and prosperity entered history at a time dominated by I-Like-Ike politics and domestic security. As they approached adolescence, however, their world was shaken by major cultural, economic, social, and political upheaval. And although it was time of great innovation and progress, a sense of chaos and bitterness began to envelop the country. It was the '60s. For many Americans, a mere mention of this decade evokes an extraordinary time and place in the country's - and their own - history. Adolescents who had been enjoying the technological and medical advances of the era - television, drive-in movies, rock-and-roll, vaccinations that prevented once-incurable diseases - now were also experiencing the fallout from the Civil Rights Movement, domestic terrorism, stagflation, and (perhaps most significant) the Vietnam War. From Adolescence to Adulthood in the Vietnam Era provides a unique, detailed, long-term study of the psychological and social worlds of male adolescents who were on the cusp of adulthood as the 1960s were ending. This longitudinal analysis follows adolescent boys who graduated with the class of 1969 and transitioned into adulthood either through military service, full-time employment, or college life. The results examine the different pathways these boys chose and the affect these choices had on their transition from adolescents to young adult men.
During the last two decades silicon-containing dendritic polymers have become one of the fastest growing areas of development in polymer science. The eruption of interest in these new polymers stems from their unprecedented molecular architecture, unique resulting properties and the realization that they represent ideal building blocks for chemical nanotechnology. This is the first book to solely focus on silicon-containing dendritic polymers. The contributions of those experts who originally introduced each field or played a major role in its progress are reported. The developments in all major areas of this field are presented from their origins to the present. It is anticipated that this text will become an invaluable guide and vanguard of reference for experienced scientists interested in the fields of polymer and material science, synthetic chemistry, and nanotechnology. It will also serve advanced graduate students either as a source of creative inspiration or as a textbook for appropriate courses.
During the last two decades silicon-containing dendritic polymers have become one of the fastest growing areas of development in polymer science. The eruption of interest in these new polymers stems from their unprecedented molecular architecture, unique resulting properties and the realization that they represent ideal building blocks for chemical nanotechnology. This is the first book to solely focus on silicon-containing dendritic polymers. The contributions of those experts who originally introduced each field or played a major role in its progress are reported. The developments in all major areas of this field are presented from their origins to the present. It is anticipated that this text will become an invaluable guide and vanguard of reference for experienced scientists interested in the fields of polymer and material science, synthetic chemistry, and nanotechnology. It will also serve advanced graduate students either as a source of creative inspiration or as a textbook for appropriate courses.
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control Has datasets, programming code, and practice exercises with solutions, available on a supplementary website
Children born during the post-WWII era of peace and prosperity entered history at a time dominated by I-Like-Ike politics and domestic security. As they approached adolescence, however, their world was shaken by major cultural, economic, social, and political upheaval. And although it was time of great innovation and progress, a sense of chaos and bitterness began to envelop the country. It was the a ~60s. For many Americans, a mere mention of this decade evokes an extraordinary time and place in the countrya (TM)s - and their own - history. Adolescents who had been enjoying the technological and medical advances of the era - television, drive-in movies, rock-and-roll, vaccinations that prevented once-incurable diseases - now were also experiencing the fallout from the Civil Rights Movement, domestic terrorism, stagflation, and (perhaps most significant) the Vietnam War. From Adolescence to Adulthood in the Vietnam Era provides a unique, detailed, long-term study of the psychological and social worlds of male adolescents who were on the cusp of adulthood as the 1960s were ending. This longitudinal analysis follows adolescent boys who graduated with the class of 1969 and transitioned into adulthood either through military service, full-time employment, or college life. The results examine the different pathways these boys chose and the affect these choices had on their transition from adolescents to young adult men.
This volume is presented in four sections based on recent research in the field: the sources of identity, the tie between identity and the social structure, the non-cognitive outcomes - such as emotional - of identity processes, and the idea that individuals have multiple identities. This timely work will be of interest to social psychologists in sociology and psychology, behavioral scientists, and political scientists.
In 1987 a major breakthrough occurred in materials science. A new family of materials was discovered that became superconducting above the temperature at which nitrogen gas liquifies, namely, 77 K or -196 DegreesC. Within months of the discovery, a wide variety of experimental techniques were brought to bear in order to measure the properties of these materials and to gain an understanding of why they superconduct at such high temperatures. Among the techniques used were electromagnetic absorption in both the normal and the superconducting states. The measurements enabled the determination of a wide variety of properties, and in some instances led to the observation of new effects not seen by other measu- ments, such as the existence of weak-link microwave absorption at low dc magnetic fields. The number of different properties and the degree of detail that can be obtained from magnetic field- and temperature-dependent studies of electromagnetic abso- tion are not widely appreciated. For example, these measurements can provide information on the band gap, critical fields, the H-T irreversibility line, the amount of trapped flux, and even information about the symmetry of the wave function of the Cooper pairs. It is possible to use low dc magnetic field-induced absorption of microwaves with derivative detection to verify the presence of superconductivity in a matter of minutes, and the measurements are often more straightforward than others. For example, they do not require the physical contact with the sample that is necessary when using four-probe resistivity to detect superconductivity.
In The New Superconductors, Frank J. Owens and Charles P. Poole, Jr., offer a descriptive, non-mathematical presentation of the latest superconductors and their properties for the non-specialist. Highlights of this up-to-date text include chapters on superfluidity, the latest copper oxide types, fullerenes, and prospects for future research. The book also features many examples of commercial applications; an extensive glossary that defines superconductivity terms in clear language; and a supplementary list of readings for the interested lay reader.
This updated and expanded volume reflects the current state of the structural protein field with improved and refined protocols that have been applied to particularly challenging proteins. Beginning with a section on structural bioinformatics, the book continues with sections covering the challenge of producing high quality samples for structural studies, particularly mammalian membrane proteins and protein complexes, as well as protocols for structure determination, including the use of electrons in structural biology and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Structural Proteomics: High-Throughput Methods, Third Edition will aid researchers in expanding our knowledge of this vital and expansive area of protein science. Chapter 9 is available open access under a CC BY 4.0 license.
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