This book tells the extraordinary story of how the function of the first - and so far almost the only - human organ was replaced by a machine, and the "artificial kidney" entered medical and public folk-lore. A practical artificial kidney, or dialyser, came about by advances in science followed by the acquisition of new synthetic materials which made the application of these ideas possible. However it was the dedication and persistence of a number of talented pioneers who pressed ahead against professional opposition to achieve success, first in the treatment of temporary, recoverable kidney failure, and then permanent renal shut-down which made it a success. The apparent high cost and limited availability of this form of treatment immediately raised ethical questions which had never been questioned before, centering around equity of access to treatment, when and if treatment could be denied, and - worst of all - the agonising decision of when, once established, it should be stopped. Spiralling costs as the true number of people with kidney failure became evident raised major political and financial questions, which were addressed in different countries in different ways which reflected - but also helped change - patterns of how medical care is provided. In developed countries, the problem could be solved by allocating a disproportionate amount of money to the treatment of relatively few kidney patients, but in the developing world the cost of treatment still limits its availability, as it does all forms of modern health care. Nevertheless, today almost one million people world-wide are maintained alive following terminal kidney failure, two thirds of them by various forms of dialysis and the remainder bearing kidney transplants, almost always placed after a period on dialysis. The story is also the sum of the often heroic lives of these hundreds of thousands of patients, a few of whom have today been maintained alive and active for more than 35 years, and many of whom suffered known, but also unexpected complications as a result of their treatment.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field.  Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

The authors present a historical picture of gender relations in Highlands New Guinea by exploring domains of imagination as revealed in courting songs, ballads, and folktales from across the Highlands but with particular reference to field areas in the western Highlands. Texts and/or translations are from a rich corpus of materials previously unpublished in English. The examples draw the reader into the imaginative world of the people, while the analytical framework sets the discussion firmly into debates within interpretive anthropology.

The aim is to re-examine the images of gender relations in Highlands New Guinea by revealing the sensuous and emotional modalities of expressive folk genres and their aesthetic qualities. Ideas and practices centered on female spirit entities are shown to be important and pervasive in cult contexts, and these spirits were felt to have a significant influence on relations of courtship, marriage, and reproduction. Both women and men are also shown to have complex expressions of emotional dispositions in the spheres of courting and the choice of marital partners. By entering into these domains, the book modifies earlier analyses that have concentrated on antagonism, behavioral taboos, separation, and domination as themes in gender relations in Highland societies.

The economy is global, businesses are increasingly global, management has gone global and there is an increasing demand (and reward) for truly skilled global leaders, managers and executives. Black and Morrison address this change by asking why and when globalization truly began and explain how businesses can adapt themselves to remain competitive in increasingly global markets. Written by authoritative experts and based on extensive, up-to-date research and interviews with leading global leaders, The Global Leadership Challenge provides practical tools to develop global leadership skills, laying down the capabilities that must be developed and the plans that must be made to meet the globalization challenge. This will be truly vital reading for middle managers who have ambition for more senior positions, senior managers that are already bumping up against the challenges of global leadership, and top executives who are in the midst of the challenges of global leadership.

Thomas F Walsh tells the story of one of the West's wealthiest mining magnates -- an Irish American prospector and lifelong philanthropist who struck it rich in Ouray County, Colorado. In the first complete biography of Thomas Walsh, John Stewart recounts the tycoon's life from his birth in 1850 and his beginnings as a millwright and carpenter in Ireland to his tenacious, often fruitless mining work in the Black Hills and Colorado, which finally led to his discovery of an extremely rich vein of gold ore in the Imogene Basin. Walsh's Camp Bird Mine yielded more than $20 million worth of gold and other minerals in twenty years, and the mine's 1902 sale to British investors made Walsh very wealthy. He achieved national prominence, living with his family in mansions in Colorado and Washington DC, and maintaining a rapport with Presidents McKinley, Theodore Roosevelt, and Taft, as well as King Leopold II of Belgium. Despite his fame and lavish lifestyle, Walsh is remembered as an unassuming and philanthropic man who treated his employees well. In addition to making many anonymous donations, he established the Walsh Library in Ouray and a library near his Irish birthplace, and helped establish a research fund for the study of radium and other rare western minerals at the Colorado School of Mines. Walsh gave his employees at the Camp Bird Mine top pay and lodged them in an alpine boarding-house featuring porcelain basins, electric lighting, and excellent food. Stewart's engaging account explores the exceptional path of this Colorado mogul in detail, bringing Walsh and his time to life.

This book considers in depth the emergent theme of concerns over bodily fluids in health and wellness through an examination of a rich set of ethnographic materials from the Pacific islands of New Guinea. The particular structure of the book draws together otherwise disparate observations made by ethnographers on ideas of the body. It helps to reveal how these are related to ideas of sickness and curing, of witchcraft, of cannibalism, of gender relations, and of ecology and ritual. It facilitates cross-cultural comparisons with other parts of the world, as well as making clear the fundamental similarities between the societies of Irian Jaya and Papua New Guinea.

It also discusses the idea of the cosmos and its centrality to ideological representations of the physical and social body. Society is seen to be part of the cosmos, and the human body directly linked to, and in cyclical flow with, the elements of the life-world in general, and society in particular.

Committed to continued excellence in establishing in-depth and comprehensive safety and security awareness and protection education for the public; Killing Our Children: Mass Shooters in the U.S. is, without a doubt, a bold and engaging look at mass killers in America, how they're abhorrently slaughtering our children, and the "conversations" parents must have with their children in order to educate and keep safe our nation's most valuable resource. At its best, Killing Our Children- Mass Shooters in the U.S. demands both conversation and action; re-engaging the discussion on gun control legislation in America, repairing flaws in our nation's mental health care system and many other critical issues affecting children today. Our most basic obligation is to support the healthy development of our nation's children. We are not powerless, and this is not our new normal. No one man can save a nation, and doing nothing has severe consequences for our children's future. If we don't act now to protect our children today, tomorrow may be too late.

Ritual has emerged as a major focus of academic interest. As a concept, the idea of ritual integrates the study of behavior both within and beyond the domain of religion. Ritual can be both secular and religious in character. There is renewed interest in questions such as: Why do rituals exist at all? What has been, and continues to be, their place in society? How do they change over time? Such questions exist against a backdrop of assumptions about development, modernization, and disenchantment of the world.Written with the specific needs of students of religious studies in mind, " Ritual: Key Concepts in Religion" surveys the field of ritual studies looking at it both historically within anthropology and in terms of its contemporary relevance to mass phenomena.

This book offers a fresh context for the ground-breaking work of the great mathematician Andrei Markov. A distinguished collection of scholars and scientists provide exciting new insights into the signifiance and contemporary applicability of Markov's work. (Mathematics)

This volume will be a reliable source on the management of the elderly with renal disease. There is an ever-increasing proportion of the aging population affected by renal disease and hypertension, and physicians are faced with atypical clinical presentations of renal disease in the aged as compared to younger people. This volume combines the fields of nephrology and geriatrics and presents a multidisciplinary approach to the topic.

The authors use regulation to explain the antecedents to current welfare developments in Britain. They show how first a Conservative and more recently "New Labour" governments have used in-work benefits so that today they have become the preferred instrument of intervention in the labor market for setting wages. The authors discuss the ways in which these measures address issues of child poverty and the adequacy of incomes, and how far they are disciplining devices to encourage a new moral order.

Computations with Markov Chains presents the edited and reviewed proceedings of the Second International Workshop on the Numerical Solution of Markov Chains, held January 16--18, 1995, in Raleigh, North Carolina. New developments of particular interest include recent work on stability and conditioning, Krylov subspace-based methods for transient solutions, quadratic convergent procedures for matrix geometric problems, further analysis of the GTH algorithm, the arrival of stochastic automata networks at the forefront of modelling stratagems, and more. An authoritative overview of the field for applied probabilists, numerical analysts and systems modelers, including computer scientists and engineers.

Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.