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Within the last few years, knowledge about vitamins has increased
dramatically, resulting in improved understanding of human
requirements for many vitamins. This new edition of a bestseller
presents comprehensive summaries that analyze the chemical,
physiological, and nutritional relationships, as well as highlight
newly identified functions, for all recognized vitamins. These
include vitamins A, D, K, E, B6, B12, niacin, riboflavin, thiamine,
pantothenic acid, biotin, folate, choline, and ascorbic acid.
Keeping the tradition of the previous volumes, the Handbook of
Vitamins, Fifth Edition provides an updated, contemporary
perspective on vitamins in human nutrition. Bringing together
leading experts in molecular biology, biochemistry, and physiology,
the book contains substantial revisions in every chapter, covering
vitamin metabolism, including human requirements, clinical aspects
of deficiency, vitamin-dependant cell signals and gene regulation,
and roles as coenzymes. The chapter on epigenetics has been updated
and expanded to include novel findings about vitamins not
previously considered in studies of nutrient-dependent epigenome
modification. The book also contains a new chapter on genome
stability, highlighting current understanding of vitamin-genome
interactions in the evolution of the human genome and the
functional consequences of human genetic variation. Maintaining its
status as a high-quality reference, this handbook incorporates new
discoveries into an updated and revised fifth edition.
Molecular nutrition (the study of interactions between nutrients
and various intracellular and extracellular molecules) is one of
the most rapidly developing fields in nutritional science.
Ultimately, molecular nutrition research will reveal how nutrients
may affect fundamental processes such as DNA repair, cell
proliferation, and apoptosis. This book is the only single complete
volume available reviewing the field of molecular nutrition. It
contains contributions from leading international experts, and
reviews the most important and latest research from various areas
of molecular nutrition.
Cell signaling is at the core of most biological processes from the
simplest to the most complex. In addition to unicellular organisms
possessing the essential ability to receive inputs with regard to
nutrient availability and noxious stimuli, the cells in
multicellular organisms require signaling from adjacent, as well as
distant cells to maintain normal internal function, including
growth, differentiation, and homeostasis. Conversely, the etiology
of many disease processes, such as those involving immune system
dysfunction and tumor development, have been traced to aberrant
cell signaling. Nutrients and Cell Signaling, in presenting
contributions from a wide array of experts in the field, fully
delineates the role of nutrients in cell signaling. The text
emphasizes broad concepts and covers all major groups of nutrients.
Contributors discuss the role of carbohydrates, amino acids,
lipids, vitamins, minerals, and trace elements in essential
processes such as cell proliferation, immune function, and DNA
repair. The editors have organized the work to provide select
examples organized under these contemporary research areas: Nuclear
receptors, transcription factors, and signaling cascades Amino
acids, lipids, and glycation Insulin release, signaling, and
insulin resistance Calcium-dependent signaling Feeding and nutrient
homeostasis Nutrients and Cell Signaling answers the need in the
post-genomic era, for an authoritative resource that provides an
in-depth understanding of how these complex and dynamic
biomolecular networks control cell function. Those professionals
and students in molecular biology, nutrition, biochemistry, as well
as any branch involved with cell signaling and function will find
this book to be an invaluable tool in promoting both understanding
and further inquiry.
Cell signaling is at the core of most biological processes from the
simplest to the most complex. In addition to unicellular organisms
possessing the essential ability to receive inputs with regard to
nutrient availability and noxious stimuli, the cells in
multicellular organisms require signaling from adjacent, as well as
distant cells to maintain normal internal function, including
growth, differentiation, and homeostasis. Conversely, the etiology
of many disease processes, such as those involving immune system
dysfunction and tumor development, have been traced to aberrant
cell signaling. Nutrients and Cell Signaling, in presenting
contributions from a wide array of experts in the field, fully
delineates the role of nutrients in cell signaling. The text
emphasizes broad concepts and covers all major groups of nutrients.
Contributors discuss the role of carbohydrates, amino acids,
lipids, vitamins, minerals, and trace elements in essential
processes such as cell proliferation, immune function, and DNA
repair. The editors have organized the work to provide select
examples organized under these contemporary research areas:
-Nuclear receptors, transcription factors, and signaling cascades
-Amino acids, lipids, and glycation -Insulin release, signaling,
and insulin resistance -Calcium-dependent signaling -Feeding and
nutrient homeostasis Nutrients and Cell Signaling answers the need
in the post-genomic era, for an authoritative resource that
provides an in-depth understanding of how these complex and dynamic
biomolecular networks control cell function. Those professionals
and students in molecular biology, nutrition, biochemistry, as well
as any branch involved with cell signaling andfunction will find
this book to be an invaluable tool in promoting both understanding
and further inquiry.
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