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Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Paperback, Softcover reprint of the original 1st ed.... Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Paperback, Softcover reprint of the original 1st ed. 2014)
Jean-Jacques Feige, Gilles Pagès, Fabrice Soncin
R4,766 Discovery Miles 47 660 Ships in 10 - 15 working days

Angiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells…) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable blood proof neovessels. This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization. The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society.

Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Hardcover, 2014 ed.): Jean-Jacques Feige, Gilles Pages,... Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Hardcover, 2014 ed.)
Jean-Jacques Feige, Gilles Pages, Fabrice Soncin
R6,295 Discovery Miles 62 950 Ships in 10 - 15 working days

Angiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells ) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable blood proof neovessels.

This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization.

The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society."

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