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Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R4,766
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Molecular Mechanisms of Angiogenesis - From Ontogenesis to Oncogenesis (Paperback, Softcover reprint of the original 1st ed. 2014)
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Angiogenesis is a multi-stage process that drives the generation of
new blood and lymphatic vessels from pre-existing ones. It is
highly active during embryogenesis, largely inactive during
adulthood but reactivated during wound healing and under a number
of pathological conditions including cancer and ocular diseases. In
addition to endothelial cells, which line the walls of the vessels,
several other cell types (pericytes, macrophages, progenitor
cells…) also contribute to angiogenesis. A number of signaling
pathways are activated and very finely tune the delicate
morphogenetic events that ultimately lead to the formation of
stable blood proof neovessels. This book reviews recent advances in
our understanding of the molecular and cellular mechanisms of
angiogenesis, with a focus on how to integrate these observations
into the context of developmental, post-natal and pathological
neovascularization. The book was published under the auspices of
the French Angiogenesis Society. Most contributors are prominent
members of this Society or international researchers who have
actively contributed to the Annual Meetings of the Society.
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