This book constitutes the refereed proceedings of the 7th China Conference on Knowledge Graph and Semantic Computing: Knowledge Graph Empowers the Digital Economy, CCKS 2022, in Qinhuangdao, China, August 24-27, 2022. The 15 full papers and 2 short papers included in this book were carefully reviewed and selected from 100 submissions. They were organized in topical sections as follows: knowledge representation and reasoning; knowledge acquisition and knowledge base construction; linked data, knowledge integration, and knowledge graph storage managements; natural language understanding and semantic computing; knowledge graph applications; and knowledge graph open resources.