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DNA-chip analysis has come a long way since the first conference in
Moscow in 1991. Nowadays, DNA-microarrays seem to be a common
commodity in biological sciences. The complexity hidden behind the
apparent ease of such studies, however, is highlighted by the fact
that it took about ten years before the methodology really set off.
Also, on closer scrutiny, one realises that some problems still
remain. Nevertheless, microarrays produce data on a scale beyond
imagination a few years ago. The authors of the book took part in
bringing this about. They are well-known experts in the field, many
- like Edwin Southern, Hans Lehrach, Radoje Drmanac, Pavel Pevzner
and Charles Cantor - have been actively pursuing array technology
for more than a decade. They demonstrate the continuous development
in both technology and application areas and elucidate on critical
points that need to be considered when performing microarray
analyses.
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