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Mr. Blok (Hardcover)
Gregor Piatigorsky; Introduction by Joram Piatigorsky
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R704
R597
Discovery Miles 5 970
Save R107 (15%)
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Ships in 10 - 15 working days
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"Gene sharing" means that the different functions of a protein may
share the same gene--that is, a protein produced by a gene evolved
to fulfill a specialized function for one biological role may also
perform alternate functions for other biological roles.
In the 1980s and early 1990s, Joram Piatigorsky and colleagues
coined the term "gene sharing" to describe the use of
multifunctional proteins as crystallins in the eye lens. In "Gene
Sharing and Evolution" Piatigorsky explores the generality and
implications of gene sharing throughout evolution and argues that
most if not all proteins perform a variety of functions in the same
and in different species, and that this is a fundamental necessity
for evolution.
How is a gene identified, by its structure or its function? Do
the boundaries of a gene include its regulatory elements? What is
the influence of gene expression on natural selection of protein
functions, and how is variation in gene expression selected in
evolution? These are neither new nor resolved questions.
Piatigorsky shows us that the extensiveness of gene sharing and
protein multifunctionality offers a way of responding to these
questions that sheds light on the complex interrelationships among
genes, proteins, and evolution.
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