The Science of Human Milk offers readily understandable, scientifically sound information related to the compositional features of human milk at different stages of lactation. The book also debunks many myths about human milk and provides an analysis of the differences in human milk and baby formulas, offering suggestions for how the latter can be improved. The correlation between human milk composition and infant physiology and metabolism, growth, development, health and disease is explored in detail, placing emphasis on preterm infants. In addition, the dynamic nature of human milk, including its microbes, immunology, metabolites, cell components and epigenetically active molecules are covered. Written for researchers working in nutrition and neonatology, as well as health care professionals working in related fields, this book is sure to be a welcomed reference.

The Microbiome in Prenatal and Neonatal Life clarifies that the microbiome in the maternal fetal unit and immediate changes that occur as new microbes are acquired postnatally play major roles in subsequent health and disease. Rapidly developing technologies for multi-omic analyses and systems biology are shifting paradigms in both scientific knowledge and clinical care with regard to this topic. In essence, we are changing the idea that newborns emerge from sterile environments. As such, in-utero colonization may have impacts on the development of immunity and metabolism that, with epigenetic modifications, will lead to diseases in later life. In addition, the microbial profile that develops during and after birth depends on mode of delivery, type of feeding (human milk versus formula), and various other environmental factors to which the newborn is exposed.

Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient.The thoroughly updated, full-color, 4th Edition of Gastroenterology and Nutrition: Provides in-depth clinical overviews of both common and rare neonatal GI and nutritional disorders, offering guidance based on the most up-to-date understanding of underlying pathophysiology. Places emphasis on controversial areas that can entail different approaches. Features the most current clinical information throughout, including the dynamic composition of human milk for precision nutrition, how the developmental biology of the GI tract relates to optimizing nutrition for the most vulnerable infants, interactions of the gut with the brain and other organs, associations between the GI tract and nutritional health and disease with individual nutrients, microbes, and metabolites, and more. Covers rapidly emerging technologies such as artificial intelligence and multiomics for predictive analytics, as well as in augmenting our understanding of mechanisms of pathophysiology. Discusses how diagnoses such as sepsis, bronchopulmonary dysplasia, and central nervous system disorders relate to a breakdown of homeostasis in the intestinal tract. Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout. Offers the most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles! Gastroenterology and Nutrition Hematology and Transfusion Medicine Neonatal Hemodynamics Infectious Disease, Immunology, and Pharmacology Renal, Fluid, and Electrolyte Disorders Neurology The Newborn Lung

The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in perinatology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to the clinical management of your patients. There's no faster or easier way to stay informed! Chapters include The Fetus; Genetatics and Teratology; Respiratory Disorders; Infectious Diseases and Immunology; Cardiovascular System; Gastrointestinal Health and Nutrition; and Hematology, to name a few.