![]() |
![]() |
Your cart is empty |
||
Showing 1 - 2 of 2 matches in All Departments
The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the "world of naked gene vaccines", namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing "burning questions".
The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the "world of naked gene vaccines", namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing "burning questions".
|
![]() ![]() You may like...
Kagiso Reader: Lehumo goba matlakala…
Barbara Coombe, Heather Moore, …
Paperback
R85
Discovery Miles 850
Kagiso Reader: Mangwalo a mabedi (NCS…
Barbara Coombe, Heather Moore, …
Paperback
R81
Discovery Miles 810
Kagiso Reader: Legae la me (NCS): Grade…
Barbara Coombe, Heather Moore, …
Paperback
R73
Discovery Miles 730
Lied Vir Sarah - Lesse Van My Ma
Jonathan Jansen, Naomi Jansen
Hardcover
![]()
|