Science and public policy go hand in hand, yet their relationship is fraught with tension. Society demands innovation through new research and technology, as well as ensuring that scientific progress is socially acceptable and sustainable. This Handbook examines the fluctuating relationship between public policy and science, and in particular the impact, both nationally and internationally of these changes on research. Examining the interlinked models of science and social policy, this Handbook addresses a number of overarching questions: what are the consequences of changing science policies for science and science systems? How far do these consequences go? Do they tackle the fundamental principles of science, its norms, standards, and reputation systems? And what impact does this have on modern science and technology? With contributions from leading scholars in the field, the Handbook on Science and Public Policy provides answers from a broad scope of theoretical and conceptual perspectives. This is a much-needed reference for students of public policy and politics, as well as for scholars with an interest in science policy in particular. The wide range of insights will also be of interest to analysts of science policy.