|
Showing 1 - 16 of
16 matches in All Departments
The thoroughly revised edition of Vander's Human Physiology is an
integrated package of textual and digital material that delivers
basic and clinical content, real-life applications, and educational
technologies. All these pieces come together to facilitate learning
and enthusiasm for understanding the mechanisms of body function.
Key focus areas include homeostasis, exercise, and human health.
These and other areas of interest are elaborated upon, beginning
with Chapter 1, where the key "General Principles of Physiology,"
an underlying theme in the book, is first introduced. Unifying
themes, such as homeostasis, are explored throughout the book at
all levels of system, organ, tissue, and cellular function-themes
that are always related to pathophysiology through the use of
compelling clinical case studies in all chapters, and a final
chapter with several cases that integrate material across the
entire book.
Nonmammalian model organisms have become a cornerstone of systems
biology research. Like the Rosetta Stone, which enabled modern
scholars to decode ancient Egyptian hieroglyphics, model organisms
enable biologists to decipher the genetic code underlying the
complex physiological processes common to all life. C. elegans
provides a particularly striking example of the experimental
utility of model organisms. Genetic, molecular and systems
biological characterization of this organism is greatly facilitated
by its short life cycle and high rate reproduction, and by the ease
with which it can be cultured in the laboratory. C. elegans also
has a fully sequenced and well-annotated genome, which is assembled
in readily accessible public databases along with virtually all
other biological data on this organism.
C. elegans: Methods and Applications aims to enhance the readily
available methodologies for the study of C. elegans by providing
overviews and concise, step-by-step descriptions of the most
state-of-the-art methods currently being utilized in the field.
Some of the methods presented include forward and reverse genetic
analysis, data mining and comparative genomics strategies, electron
and fluorescence microscopy methods, automated imaging methods for
worm behavioral analysis, functional genomics strategies, and
cutting-edge methods for physiological analyses. This comprehensive
collection of methods, written by experts in the field, endeavors
to serve as a roadmap for researchers, illustrating the type or
research that is possible with C. elegans, and illuminating its
potential as a vehicle for future discovery.
Molecular biology has driven a powerful reductionist, or
"molecule-c- tric," approach to biological research in the last
half of the 20th century. Red- tionism is the attempt to explain
complex phenomena by defining the functional properties of the
individual components of the system. Bloom (1) has referred to the
post-genome sequencing era as the end of "naive reductionism. "
Red- tionist methods will continue to be an essential element of
all biological research efforts, but "naive reductionism," the
belief that reductionism alone can lead to a complete understanding
of living organisms, is not tenable. Organisms are clearly much
more than the sum of their parts, and the behavior of complex
physiological processes cannot be understood simply by knowing how
the parts work in isolation. Systems biology has emerged in the
wake of genome sequencing as the s- cessor to reductionism (2-5).
The "systems" of systems biology are defined over a wide span of
complexity ranging from two macromolecules that interact to carry
out a specific task to whole organisms. Systems biology is
integrative and seeks to understand and predict the behavior or
"emergent" properties of complex, multicomponent biological
processes. A systems-level characteri- tion of a biological process
addresses the following three main questions: (1) What are the
parts of the system (i. e."
|
McHumans (Paperback)
Sean Ferrari; Illustrated by Luke Spooner; Kevin Strange
|
R222
Discovery Miles 2 220
|
Ships in 10 - 15 working days
|
How do the benefits of higher education compare with its costs, and
how does this comparison vary across individuals and institutions?
These questions are fundamental to quantifying the productivity of
the education sector. The studies in Productivity in Higher
Education use rich and novel administrative data, modern
econometric methods, and careful institutional analysis to explore
productivity issues. The authors examine the returns to
undergraduate education, differences in costs by major, the
productivity of for-profit schools, the productivity of various
types of faculty and of outcomes, the effects of online education
on the higher education market, and the ways in which the
productivity of different institutions responds to market forces.
The analyses recognize five key challenges to assessing
productivity in higher education: the potential for multiple
student outcomes in terms of skills, earnings, invention, and
employment; the fact that colleges and universities are
"multiproduct" firms that conduct varied activities across many
domains; the fact that students select which school to attend based
in part on their aptitude; the difficulty of attributing outcomes
to individual institutions when students attend more than one; and
the possibility that some of the benefits of higher education may
arise from the system as a whole rather than from a single
institution. The findings and the approaches illustrated can
facilitate decision-making processes in higher education.
|
Computerface (Paperback)
Sean Ferrari; Illustrated by Luke Spooner; Kevin Strange
|
R252
Discovery Miles 2 520
|
Ships in 10 - 15 working days
|
|
Robamapocalypse (Paperback)
Sean Ferrari; Illustrated by Jesse Wheeler; Kevin Strange
|
R249
Discovery Miles 2 490
|
Ships in 10 - 15 working days
|
|
Beetle Brain (Paperback)
Sean Ferrari; Illustrated by Willaim Skaar; Kevin Strange
|
R294
Discovery Miles 2 940
|
Ships in 10 - 15 working days
|
|
Cotton Candy (Paperback)
Sean Ferrari; Illustrated by Shamus Beyale; Kevin Strange
|
R222
Discovery Miles 2 220
|
Ships in 10 - 15 working days
|
|
|