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C. elegans - Methods and Applications (Hardcover, 2006 ed.)
Loot Price: R2,819
Discovery Miles 28 190
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C. elegans - Methods and Applications (Hardcover, 2006 ed.)
Series: Methods in Molecular Biology, 351
Expected to ship within 10 - 15 working days
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Nonmammalian model organisms have become a cornerstone of systems
biology research. Like the Rosetta Stone, which enabled modern
scholars to decode ancient Egyptian hieroglyphics, model organisms
enable biologists to decipher the genetic code underlying the
complex physiological processes common to all life. C. elegans
provides a particularly striking example of the experimental
utility of model organisms. Genetic, molecular and systems
biological characterization of this organism is greatly facilitated
by its short life cycle and high rate reproduction, and by the ease
with which it can be cultured in the laboratory. C. elegans also
has a fully sequenced and well-annotated genome, which is assembled
in readily accessible public databases along with virtually all
other biological data on this organism.
C. elegans: Methods and Applications aims to enhance the readily
available methodologies for the study of C. elegans by providing
overviews and concise, step-by-step descriptions of the most
state-of-the-art methods currently being utilized in the field.
Some of the methods presented include forward and reverse genetic
analysis, data mining and comparative genomics strategies, electron
and fluorescence microscopy methods, automated imaging methods for
worm behavioral analysis, functional genomics strategies, and
cutting-edge methods for physiological analyses. This comprehensive
collection of methods, written by experts in the field, endeavors
to serve as a roadmap for researchers, illustrating the type or
research that is possible with C. elegans, and illuminating its
potential as a vehicle for future discovery.
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