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This book introduces recent progress in biological energetics from ATP hydrolysis to molecular machineries. The role of water is now recognized to be essential in biological molecular energetics. Although energetics is a rather distant field to many biologists, any working models for protein machineries such as protein motors, transporters, and other enzymes must be consistent with their energetics. Therefore, the book is intended to help scientists build systematic models of biomolecular functions based on three categories: (1) ATP hydrolysis reactions including ionic hydration and protonation-deprotonation of biomolecules, (2) protein-ligand/protein-protein interactions including hydration-dehydration processes, and (3) functioning mechanisms of protein machineries based on water functions.
Communication of risks within a transparent and accountable framework is essential in view of increasing mobility and the complexity of the modern society and the field of geotechnical engineering does not form an exception. As a result, modern risk assessment and management are required in all aspects of geotechnical issues, such as planning, design, construction of geotechnical structures, mitigation of geo-hazards, management of large construction projects, maintenance of structures and life-cycle cost evaluation. This volume discusses: 1. Evaluation and control of uncertainties through investigation, design and construction of geotechnical structures; 2. Performance-based specifications, reliability based design and limit state design of geotechnical structures, and design code developments; 3. Risk assessment and management of geo-hazards, such as landslides, earthquakes, debris flow, etc.; 4. Risk management issues concerning large geotechnical construction projects; 5. Repair and maintenance strategies of geotechnical structures. Intended for researchers and practitioners in geotechnical, geological, infrastructure and construction engineering.
“If Americans lived more like the Okinawans, 80 percent of the nation’s coronary care units, one-third of the cancer wards, and a lot of the nursing homes would be shut down.” —From The Okinawa Program
In their "New York Times" bestseller "The Okinawa Program," Drs. Bradley and Craig Willcox and Makoto Suzuki explained why the Okinawans are the longest-lived people on earth. Now, they offer a practical diet program rooted in Okinawan traditions so that you too can have a leaner, more "metabolically efficient" body that will stay healthier and more youthful. Conveniently divided into three dietary tracks--western, eastern, and a fusion plan that combines both--their program will help you achieve healthy weight loss without deprivation. With more than 150 recipes, an eight-week phase-in plan, and other unique resources, "The Okinawa Diet Plan" is an easy-to-follow breakthrough concept in healthy weight loss.
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