Oral squamous cell carcinoma is the sixth most common malignancy and is a major cause of cancer morbidity and mortality worldwide. Recent discoveries have dramatically increased our understanding of the most basic mechanisms controlling normal cell growth, and have also greatly enhanced our ability to investigate the nature of the biological processes that lead to cancer. Mathematical models predict that 8-10 individual genetic aberrations are required for progression to head and neck cancer alongwith hundreds of genetic aberrations, the vast majority unrelated to their pathogenesis. The challenge for modern genetic analysis is to differentiate consequential genetic aberrations from the background events. However, this explosion of information on cancer-specific chromosomal aberrations can be utilized by the scientific community only if compiled in easily accessible databases

Gross pathology refers to the macroscopic manifestations of disease in organs, tissues, and body cavities. Grossing is a very important step in surgical pathology and inadequate sampling of the gross specimen can lead to misinterpretation of the slides. For oral and maxillofacial specimens, a careful gross examination and description are infinitely superior to the examination of a random microscopic section. This book provides a highly visual step by step guide to grossing procedure like inital handling of the specimen, from where to take sections, how to do reporting etc. Contains high quality photographs, illustrations and tables that will help readers to understand the topic easily. Although the book is an introductory text but it lays a solid foundation for post graduate students and prepare them for future.