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Oral squamous cell carcinoma is the sixth most common malignancy
and is a major cause of cancer morbidity and mortality worldwide.
Recent discoveries have dramatically increased our understanding of
the most basic mechanisms controlling normal cell growth, and have
also greatly enhanced our ability to investigate the nature of the
biological processes that lead to cancer. Mathematical models
predict that 8-10 individual genetic aberrations are required for
progression to head and neck cancer alongwith hundreds of genetic
aberrations, the vast majority unrelated to their pathogenesis. The
challenge for modern genetic analysis is to differentiate
consequential genetic aberrations from the background events.
However, this explosion of information on cancer-specific
chromosomal aberrations can be utilized by the scientific community
only if compiled in easily accessible databases
Gross pathology refers to the macroscopic manifestations of disease
in organs, tissues, and body cavities. Grossing is a very important
step in surgical pathology and inadequate sampling of the gross
specimen can lead to misinterpretation of the slides. For oral and
maxillofacial specimens, a careful gross examination and
description are infinitely superior to the examination of a random
microscopic section. This book provides a highly visual step by
step guide to grossing procedure like inital handling of the
specimen, from where to take sections, how to do reporting etc.
Contains high quality photographs, illustrations and tables that
will help readers to understand the topic easily. Although the book
is an introductory text but it lays a solid foundation for post
graduate students and prepare them for future.
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