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This book presents a comparison analysis of two cancer treatment
therapies: carbon ion therapy and protontherapy. It is divided in 5
sections. The first ones gives the reader a brief history of
Radiotherapy and types of radiation. In the second section, the
techniques and equipments, including new ones in development such
as Cyclinac , Laser and DWA, are described. The third section
describes biophysical (such as stopping power and LET) and
biological (such as RBE and OER) properties, the fundamental
experiments and clinical area. The fourth section presents models
and the fifth section compares both techniques, showing advantages
and disadvantages of each, and their similarities.
This book presents a comparison analysis of two cancer treatment
therapies: carbon ion therapy and protontherapy. It is divided in 5
sections. The first ones gives the reader a brief history of
Radiotherapy and types of radiation. In the second section, the
techniques and equipments, including new ones in development such
as Cyclinac , Laser and DWA, are described. The third section
describes biophysical (such as stopping power and LET) and
biological (such as RBE and OER) properties, the fundamental
experiments and clinical area. The fourth section presents models
and the fifth section compares both techniques, showing advantages
and disadvantages of each, and their similarities.
This brief provides an in-depth overview of the physics of hadron
therapy, ranging from the history to the latest contributions to
the subject. It covers the mechanisms of protons and carbon ions at
the molecular level (DNA breaks and proteins 53BP1 and RPA), the
physics and mathematics of accelerators (Cyclotron and
Synchrotron), microdosimetry measurements (with new results so far
achieved), and Monte Carlo simulations in hadron therapy using
FLUKA (CERN) and MCHIT (FIAS) software. The text also includes
information about proton therapy centers and carbon ion centers
(PTCOG), as well as a comparison and discussion of both techniques
in treatment planning and radiation monitoring. This brief is
suitable for newcomers to medical physics as well as seasoned
specialists in radiation oncology.
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