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Since its discovery in 1998, RNA interference (RNAi) has heralded
the advent of novel tools for biological research and drug
discovery. This exciting new technology is emerging as a powerful
modality for battling some of the most notoriously challenging
viral clinical targets, such as the hepatitis C virus (HCV) and the
human immunodeficiency virus (HIV). However, several critical
issues associated with this novel technology must be resolved
before it can progress to testing in human clinical trials, and
these have been the target of intensive research in recent years.
In this book, expert RNAi specialists from around the world have
teamed up to produce a timely and thought-provoking review of the
area. The two central themes are: 1) the latest findings on
RNAi-virus interactions and 2) progress in the development of
RNAi-based antiviral therapeutics. A number of chapters explain
general concepts concerned with the role of RNAi in natural
antiviral defense mechanisms. Other chapters discuss how to improve
the efficacy and safety of RNAi-based antiviral drugs, as well as
describe how this technology is being developed as a new
therapeutic tool for fighting specific viruses, including HIV, HCV,
and respiratory viruses. The book also outlines potential new
avenues for research. RNA Interference and Viruses is essential
reading for researchers involved in RNAi or antiviral research and
is a recommended text for all virology laboratories.
This edited volume advances our understanding of urban activism
beyond the social movement theorization dominated by thesis of
political opportunity structure and resource mobilization, as well
as by research based on experience from the global north. Covering
a diversity of urban actions from a broad range of countries in
both hemispheres as well as the global north and global south, this
unique collection notably focuses on non-institutionalised or
localised urban actions that have the potential to bring about
radical structural transformation of the urban system and also
addresses actions in authoritarian regimes that are too sensitive
to call themselves "movement". It addresses localized issues cut
off from international movements such as collective consumption
issues, like clean water, basic shelter, actions against
displacement or proper venues for street vendors, and argues that
the integration of the actions in cities in the global south with
the specificity of their local social and political environment is
as pivotal as their connection with global movement networks or
international NGOs. A key read for researchers and policy makers
cutting across the fields of urban sociology, political science,
public policy, geography, regional studies and housing studies,
this text provides an interdisciplinary and international
perspective on 21st century urban activism in the global north and
south.
This edited volume advances our understanding of urban activism
beyond the social movement theorization dominated by thesis of
political opportunity structure and resource mobilization, as well
as by research based on experience from the global north. Covering
a diversity of urban actions from a broad range of countries in
both hemispheres as well as the global north and global south, this
unique collection notably focuses on non-institutionalised or
localised urban actions that have the potential to bring about
radical structural transformation of the urban system and also
addresses actions in authoritarian regimes that are too sensitive
to call themselves "movement". It addresses localized issues cut
off from international movements such as collective consumption
issues, like clean water, basic shelter, actions against
displacement or proper venues for street vendors, and argues that
the integration of the actions in cities in the global south with
the specificity of their local social and political environment is
as pivotal as their connection with global movement networks or
international NGOs. A key read for researchers and policy makers
cutting across the fields of urban sociology, political science,
public policy, geography, regional studies and housing studies,
this text provides an interdisciplinary and international
perspective on 21st century urban activism in the global north and
south.
Una sola fotografia realizada desde cualquier smartphone, tablet o
camara digital lleva almacenada en el interior de la memoria de
almacenamiento que la contiene una gran cantidad de datos que
registran informaciones importantes tan dispares como la identidad
del propietario del equipo de captacion, los numeros de serie y de
registro del hardware y software de captura de imagen, las
caracteristicas tecnicas sobre las condiciones en que se realiza la
toma fotografica, e incluso datos sobre las coordenadas geograficas
en que se produce la toma de la imagen registrada o detalles sobre
las manipulaciones que haya podido sufrir una imagen digital con un
tratamiento informatico posterior al registro de la misma sobre la
memoria del equipo que produjo la captura. Que son los metadatos?
existen diferentes tipos de metadatos? cual es su utilidad en el
analisis forense de imagenes digitales por los laboratorios de
criminalistica? se pueden manipular o borrar los metadatos?, estas
son solo algunas de las preguntas a las que trata de responder el
autor a traves del contenido de este interesante trabajo de
investigacion realizado en la UAH durante 2011."
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