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RNA Interference and Viruses - Current Innovations and Future Trends (Hardcover)
Loot Price: R5,546
Discovery Miles 55 460
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RNA Interference and Viruses - Current Innovations and Future Trends (Hardcover)
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Since its discovery in 1998, RNA interference (RNAi) has heralded
the advent of novel tools for biological research and drug
discovery. This exciting new technology is emerging as a powerful
modality for battling some of the most notoriously challenging
viral clinical targets, such as the hepatitis C virus (HCV) and the
human immunodeficiency virus (HIV). However, several critical
issues associated with this novel technology must be resolved
before it can progress to testing in human clinical trials, and
these have been the target of intensive research in recent years.
In this book, expert RNAi specialists from around the world have
teamed up to produce a timely and thought-provoking review of the
area. The two central themes are: 1) the latest findings on
RNAi-virus interactions and 2) progress in the development of
RNAi-based antiviral therapeutics. A number of chapters explain
general concepts concerned with the role of RNAi in natural
antiviral defense mechanisms. Other chapters discuss how to improve
the efficacy and safety of RNAi-based antiviral drugs, as well as
describe how this technology is being developed as a new
therapeutic tool for fighting specific viruses, including HIV, HCV,
and respiratory viruses. The book also outlines potential new
avenues for research. RNA Interference and Viruses is essential
reading for researchers involved in RNAi or antiviral research and
is a recommended text for all virology laboratories.
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