This detailed volume brings together a diverse collection of stem cell-derived model-based toxicity assays, from those routinely used to those deemed to have considerable potential. With a focus on differentiated tissues, the chapters explore numerous cardiotoxicity applications as well as coverage of neurotoxicity, hepatotoxicity, and more. Written for the Methods in Pharmacology and Toxicology series, the contents of this book aim to enable adoption of these protocols in laboratories that are interested in entering the field as well as to facilitate the transfer of best practices between laboratories that are already actively pursuing these technologies. Authoritative and cutting-edge, Stem Cell-Derived Models in Toxicology serves as a vital resource for researchers aiming to improve risk assessment in drug discovery and design.

In today's dynamic global business environment where knowledge is a main asset and learning becomes the most important process, Business Education needs to employ the right practices to develop future leaders. Businesses require graduates that become true experts. But can business schools indeed create learning experiences that address the needs of the global marketplace? Can they teach students to build learning organizations?

The articles in this volume detail successful approaches developed by business educators and researchers. The approaches have been implemented to solve real problems and to provide students with the ethical and analytical abilities they will need to both compete and contribute to the betterment of others.

The thematic part of this volume focuses on the potential of interactive on-line activities to promote business and economics education. They demonstrate the benefits that learning technologies can bring and show how to overcome potential problem issues.

In today's dynamic global business environment where knowledge is a main asset and learning becomes the most important process, Business Education needs to employ the right practices to develop future leaders. Businesses require graduates that become true experts. But can business schools indeed create learning experiences that address the needs of the global marketplace? Can they teach students to build learning organizations?

The articles in this volume detail successful approaches developed by business educators and researchers. The approaches have been implemented to solve real problems and to provide students with the ethical and analytical abilities they will need to both compete and contribute to the betterment of others.

The thematic part of this volume focuses on the potential of interactive on-line activities to promote business and economics education. They demonstrate the benefits that learning technologies can bring and show how to overcome potential problem issues.

This detailed volume brings together a diverse collection of stem cell-derived model-based toxicity assays, from those routinely used to those deemed to have considerable potential. With a focus on differentiated tissues, the chapters explore numerous cardiotoxicity applications as well as coverage of neurotoxicity, hepatotoxicity, and more. Written for the Methods in Pharmacology and Toxicology series, the contents of this book aim to enable adoption of these protocols in laboratories that are interested in entering the field as well as to facilitate the transfer of best practices between laboratories that are already actively pursuing these technologies. Authoritative and cutting-edge, Stem Cell-Derived Models in Toxicology serves as a vital resource for researchers aiming to improve risk assessment in drug discovery and design.

For countless holiday-makers, a trip to the seaside resorts of the West Country used to mean travelling on the network of lines operated by the Great Western and the London and South Western railways. Before the reshaping of British Railways following the Beeching Report in 1963, a wide variety of trains operated in Devon. This book chronicles these trains during a period of dramatic change, as lines were closed down, steam traction was phased out and the thundering express and the hard-working tank disappeared. A wealth of these lost images can be found within this evocative collection of over 200 photographs. Comprising the work of both amateurs and professionals, the book also reveals glimpses of the stations, the people who worked on the lines, and of the high days and disasters. Brought together here as a collection, they pay homage to the great days of steam.

During the great age of steam, most railways in Dorset were operated by the Southern Railway and the Great Western Railway. These Dorset railway companies and daily life on the branch lines during this era and beyond are recorded here amid a wealth of informatively captioned photographs collected by authors Ted Gosling and Mike Clement. Bygone railway stations are affectionately recalled, together with the open cattle trucks and luxurious Pullman coaches that served our great -grandfathers' generation. This book is a tribute to the men who worked on the demanding coal-fired locomotives of this age for they were truly the unsung heroes of Dorset's railways.

No-one could have imagined what a revolutionary change the dawning of the railway age would have on the British countryside and its inhabitants. Somerset was no exception: the Great Western Railway, the London and South Western Railway, and the Somerset and Dorset Joint Railway operated many services throughout this beautiful county. In the age of steam and in later days these companies gave communities employment and security; their stations, crossing and engine sheds transformed the landscape and their locomotives were objects of admiration. This book aims to give the reader a chance to look back at scenes and locations that were once so common over a wonderful railway network. Stations such as Chard Junction, Milborne Port, Wellow, Chilcompton and Binegar are depicted. Somerset Railways also examines the countless trains that passed by in the age of steam: the Devon Belle and the Pines Express. Enriched by a wealth of photographs of staff from all walks of railway life, this book is a tribute to those railway workers and to the vibrant Somerset railway system that they served.

Nestled on the South Devon coast, the neighbouring settlements of Seaton and Axmouth have an enviable geographical setting and a special community spirit. In Ted Gosling and Mike Clement's new book we are treated to a fascinating snapshot of days gone by. Featured here are chapters on the community, schools, seashore, high days and holidays and local events. This is sure to be a wonderful addition to The History Press's Britain in Old Photographs series.