The crude methanolic extract and different fractions of plant Boerhavia repens were subjected to a number of biological tests for the evaluation of their pharmacological activity.The whole plant of Boerhavia repens was extracted with methanol by cold extraction method. The concentrated extract of the plant were then partitioned into pet ether, carbon tetrachloride, dichloromethane and ethyl acetate soluble fractions.The carbon tetrachloride, dichloromethane and the ethyl acetate soluble fractions of the plant showed strong anti-oxidant activity. The cytotoxicity evaluation of the plant extracts were carried out by Brine Shrimp Lethality Bioassay. The pet ether soluble fractions of the plant showed strong cytotoxic activity. The crude methanolic extract and pet ether soluble fraction at doses of 400 mg/kg exhibited strong analgesic activity, anti-inflammatory and anti-pyretic activity. The different fractions and the crude methanolic extract were also subjected to anti-microbial assay. However no fractions exhibited strong anti-microbial activity.

Medicinal plants are important source to be explored for the discovery and development of newer, safer and effective drug candidates. In medicinal plants research, bioactivity guided phytochemical research can be considered as a rational approach. The ethanopharmacological investigations of the study plant Schoenoplectus grossus was carried out for the first time ever in research lab by Professor Dr. Rahman's research group. The powdered root of this plant was extracted with methanol and fractioned by modified Kupchan partitioning method to provide petroleum ether, carbon tetrachloride, dichloromethane, and ethyl acetate soluble fractions. All fractions and methanol extract were investigated for pharmacological activities on animal model. The analgesic, antipyretic, anti-inflammatory, antihelmintic, and antidiarrheal effects were analyzed on dose dependent manner by comparing with standard reference drug. The extract was also screened out for cytotoxic, antioxidant, and thrombolytic activity by in vitro methods.

Polypharmacy practices are very common in psychiatry specially in Bangladesh.Psychiatric patients receive multiple drugs in order to have their therapeutic recovery. Both typical and atypical antipsychotic drugs are frequently prescribed by the psychiatrists. Use of multiple antipsychotic molecules may exert some sort of synergistic efficacy but cause a lot of unwanted side effects in the long run. Such a practice can adversely affect the quality of life of the corresponding patients. More rational use of antipsychotic drug should practiced in psychiatry with a view to ensuring quality of life of the psychiatric patients. Atypical antipsychotic drugs are new generation drugs and more safe for use. Besides atypical antipsychotic drugs sometimes offer some unique benefits which make them unparalleled choice.Appropriate drug should be chosen depending on the disease condition and overall benefits of the patients. Unnecessary any molecules' use should be discouraged so that adverse effects or metabolic side effects can be minimized to the least content. In this way we can expect better quality of life along with stabilized psychiatric patients.

The study was designed for phytochemical investigations of ethanolic extract of bark and leaf of Swietenia mahagoni belonging to the family of Meliaceae and evaluation of their biological activities with the special emphasis on analgesic, anti-inflammatory, anti-microbial and cytotoxic screening in different animal model. Phytochemical investigations were done by extensive analysis with high resolution proton NMR spectroscopic data. The ethanol extract of stem bark was partitioned between pet-ether, dichloromethane and methanol fractions. Chromatographic isolation of dichloromethane fraction using column chromatography followed by preparative TLC afforded tetranortriterpenoid compound. Ethanol extract and different fractions showed significant analgesic and anti-inflammatory potential.From the bio-assay of different fractions and extract, significant cytotoxic properties were evaluated whereas mild to moderate antimicrobial activity was found in this study.

Pterospermum acerifolium belonging to the family of Sterculiaceae has been studied. The work was carried out for isolation of it's secondary metabolites and evaluation of biological activities of it's bark with special emphasis on antioxidant activity, cytotoxicity, and antimicrobial activity The isolated compounds were identified by extensive analyses of their high resolution proton-NMR spectroscopic data.