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Stanazolol is a steroidal class drug. Stanazolol is a synthetic anabolic steroid with therapeutic uses in treating c1-inhibitor deficient hereditary Angioedema. Our main objective is to Development and Validation of Simple UV-Spectroscopic Method for stanazolol in bulk and Pharmaceutical dosage Form and development and Validation of RP-HPLC methods for estimation of Stanazolol in Bulk and Pharmaceutical dosage Form. Comparison of Developed and Validated RP-HPLC Method against the developed and Validated Simple Uv-Spectrophotometric Method. development of force degradation method for detection of possible impurity of Stanazolol in API and pharmaceutical dosage form.
A Honey Based Cough Syrup is a best selling product of Ayurlab Herbals Pvt. Ltd., Halol, Gujarat, India. This book contain introduction on standardization, cough and inflammation; review of literature, standardization parameters, HPTLC estimation and fingerprinting on Vasaka, Kantakari, Tulsi, Ginger, Mari, Pipplimool, Twak, Tamalpatra, Baheda, Liquorice, Kankol mirch, Banafsha and Brihat ela. Antitussive activity, antiinflammatory activity and antioxidant activity of Honey Based Cough Syrup and Compared with Developed Syrup.
The oral administration is the most convenient and commonly used method for drug delivery. Traditionally, solid oral dosage forms have been designed to release their drug load in the upper region of the gastrointestinal tract, where conditions are more suited to drug dissolutions and absorptions. Recently, greater emphasis has been placed on controlling site of drug release from oral formulations for the purposes of improving patient compliance and treatment efficiency . Many protein and peptide drugs like insulin cannot be administered through the oral route because of their degradation by the digestive enzymes of the stomach and the small intestine. Colon-specific drug delivery systems offer several potential therapeutic advantages.The opportunity to reduce adverse effects in the treatment of colonic diseases like, ulcerative colitis, colorectal cancer, Chorn's diseases and amoebiasis by topical application of drugs, active at the mucosal level The elucidation of the mode of action of some nonsteroidal anti-inflammatory drugs (NSAIDs) such as sulindac (metabolized in the colon to the active moiety, sulindac sulfide) that were found to interfere with the proliferation of co
The book provides an easy and up-to-date account of divergent vital topic in a simple, lucid and concise manner. The text of the book has been illustrated with simplified, well-labelled coloured diagrams and relevent pictures to make the sbject easy to understand and interesting to read for the students. Highlights Of The Book: - Exhaustive subject matter well supported with the relevant coloured photographs. - Contains standardization data of each ingredient of poly herbal formulation. - Also contains reviews of each ingredient. - Coloured photographs of HPTLC. - Comparative studies of in vitro acid neutralizing capacity with allopathic formulation.
The research work contains standardization, Development and pharmacological evaluation of both Marketed syrup(Ayurlab's Herbal Cough Syrup) and Developed syrup. In standardisation organoleptic, physicochemical, physical and phytochemical evauation were included. Also Heavy metal and Microbial analysis and Anti oxidant activity were done. In Development water extracts of each ingredients were prepared by spray dried method(Labultima) and hot plate method. HPTLC evaluation were done by marker compounds and fingerprinting done by comparing Rf value for particular ingredient. By HPTLC evaluation it was conclude that extracts used in preparation of syrup were genuie. It contains tables that gives easy evaluation of data, figures which gives easy visulation in 254 and 366nm. It also contains 3D image and chromatogram. In pharmacological evaluation animal activity done was antitussive activity of Herbal Cough Syrup and Developed Syrup in sulphur dioxide induced cough model using mice and anti inflammatory activity of Herbal Cough Syrup and Developed Syrup in carragenan induced rat paw oedema model and statical analysis was done using Grapgpad Prism 5 software.
Mucoadhesive drug delivery system which utilize properties of bioadhesion of certain water-soluble polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the body for extended period of time. The mucosal layer lie a number of regions of the body including the GIT, the urogenital tract, the airways, the ear, nose, mouth and eye. The oral mucosal sites differ greatly from the one another in terms of anatomy, permeability to an applied drug and their ability to retain a delivery system for a desired length of time. The Buccal and sublingual mucosal is relatively, permeable, giving rapid absorption and acceptable bioavailability of drugs and is convenient, easily accessible and generally well accepted
Herbal medicines are in great demand in the developed as well as developing countries for primary healthcare because of their biological activities, higher safety margin and lesser cost. They are number of medicinal plants in Ayurveda which required extusive study. The qualities of herbs depend on various factors, hence it is essential to establish herbal monograph and standardize the herbal drug. The plants selected for establishment of herbal monograph were based on its availability and its various therapeutic activities in various ailments mentioned in Ayurveda. Our objective of the research work was to establish herbal monograph based on pharmacognostic, phytochemicals and pharmacological parameters. This publication is most timely. I believe this comprehensive text book will be of use and great value to the students, academicians, researchers, teachers and herbal drug industry.
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