This book gathers selected high-quality research papers presented at the International Conference on Paradigms of Communication, Computing and Data Sciences (PCCDS 2021), held at the National Institute of Technology, Kurukshetra, India, during May 07-09, 2021. It discusses high-quality and cutting-edge research in the areas of advanced computing, communications, and data science techniques. The book is a collection of latest research articles in computation algorithm, communication, and data sciences, intertwined with each other for efficiency.

This book comprehensively reviews various nanodiagnostic approaches for the detection of bacterial pathogens. The initial chapter of the book discusses receptors present on bacterial cell surfaces that can be targeted for diagnostic applications. The book then presents different fluorescent nanoparticle systems that are used for bacterial detection. Further, it covers surface plasmon resonance (SPR), ELISA, and QCM-based nanosensors to detect pathogenic bacteria. It examines different nanosensors used for the microfluidic-based detection of bacterial pathogens, including microfluidic paper-based analytical devices (μPADs), lateral flow devices, and miniaturized PCR devices. The book also covers the current electrochemical, voltammetric, and amperometric nanosensors-based microorganism recognition approaches. Lastly, the book summarizes the current challenges and the futuristic application of nanosensors to detect bacterial pathogens. This book is an invaluable resource for all medical laboratories and clinical institutions dealing with infectious diseases.

Although green innovation and technology is not new, so far very limited information is available regarding the diversified approaches for green technologies and engineering. This book highlights the challenges and opportunities, offering a roadmap for using various approaches in the most cost effective way. The book discusses the interrelationship between a circular economy and green technologies. It presents the dimensions of green innovations and illustrates the challenges of industrialization, especially in terms of material synthesis and utilized processes. It covers the current environmental and health challenges of societies and describes the role of stakeholders in developing sustainable societies and industries. This book provides a line of approach to core and interdisciplinary students, academicians, research scientists, and various industry personnel to present their ideas of green innovations with a common vision of sustainable development of community and industries in mind. Features Discusses the interrelationship between a circular economy and green technologies Presents the dimensions of green innovations Illustrates the challenges of industrialization, especially in terms of material synthesis and utilized processes Covers the current environmental and health challenges of societies Offers the identification and role of stakeholders in the sustainable development of societies and industries

This book gathers selected high-quality research papers presented at the International Conference on Paradigms of Communication, Computing and Data Sciences (PCCDS 2021), held at the National Institute of Technology, Kurukshetra, India, during May 07-09, 2021. It discusses high-quality and cutting-edge research in the areas of advanced computing, communications, and data science techniques. The book is a collection of latest research articles in computation algorithm, communication, and data sciences, intertwined with each other for efficiency.

Bioaerosols Emission from Anthropogenic Sources: Influencing Factors, Microbial Diversity, Epidemiological Threats, and Control Approaches covers various sources of biohazards and their associated risk factors. These air contaminants are developing concerns to people and the environment and must be addressed to avert future dangers. As little is known about their precise sources, controlling variables, microbial diversity, the involvement of co-pollutants, and dispersion and control methods, this book  will assist stakeholders, including the public, government officials, and policymakers in developing successful strategies for ensuring society's safety.

Cancer is a disease characterized by reduction or loss of effectiveness in normal cellular control mechanism which regulates multiplication. A normal cell turns into a cancer cell because of one or more mutations in its DNA, which can be acquired or inherited. In the body, every cell type has its own unmatched signature, referred to as biomarkers, they are useful in the diagnosis, monitoring and in predicting the disease progression. It is found that the mediators of inflammation are important constituents of the local environment of tumors. In some types of cancer, inflammatory conditions are present before a malignant change develops. Conversely, in other types of cancer, an oncogenic change induces an inflammatory microenvironment which promotes the tumor development. In some cases, use of NSAIDs is associated with lower risks for esophageal, gastric and colon cancers as well as other solid tumors. Chronic intake of NSAIDs may reduce carcinogenesis by inhibiting production of PGs, cytokines and angiogenic factors. Moreover, the ability of these NSAIDs drugs to prevent cancer is thought to be due, in part, to COX inhibition.

This book deals with the concept of isosterism, bioisosterism and retroisosterism. Specifically it gives the bioisosteric correlation of tetrazole moiety with carboxylic group with the help of different parameters and theories. Carboxylic group is chiefly presents in proteins and peptides, thus emphasis is laid on the fact that how this carboxylic acid has been replaced by the tetrazoles in development of new chemical entities which are under clinical trials and others which are prevailing as drugs in market. Effective results in pharmacokinetic and pharmacodynamic properties of compounds have been observed. This book also highlights the effect of tetrazoles in place of carboxylic groups, studied specifically as templates in growth hormone, as in anti-HIV agents and as modifier of enzyme activity. Lastly it gives the idea of retroisosterism which is based on the inversion of a determined functional group present in the lead compound structure. Furthermore, the role of bioisosters in drug development and drug discovery is briefly discussed along with the future prospects.