This unique work from acclaimed author Dr. Paul Marino (Marino’s The ICU Book, The Little ICU Book) challenges the traditional notion that the human body thrives on oxygen, and that promoting tissue oxygenation is necessary for promoting life. This concept fails to recognize that oxygen is a destructive molecule that also damages the human body.  Instead of welcoming oxygen, the human body limits exposure of the tissues to oxygen, and employs an army of chemical antioxidants to combat the damaging effects of oxygen.  This “oxygen protective� human design represents a new paradigm for the relationship between oxygen and human survival, and it has important implications for the excessive and unregulated use of oxygen in clinical practice. Dr. Marino’s book includes the following  relevant features: Describes how oxygen and its reactive derivatives can damage vital cell components, and how oxygen plays a pivotal role in the damaging effects of inflammation, radiation, and aging. Challenges the traditional notion that oxygen delivery is the principal function of the cardiorespiratory system, and that oxygen transport is the principal function of red blood cells and hemoglobin. Demonstrates how the tissues normally operate in an oxygen-poor environment (which limits the risk of oxidative damage), and how the body counteracts attempts to increase tissue oxygenation. Describes the body’s use of protective antioxidants, and shows how failure to maintain this antioxidant protection makes oxygen inhalation an unrecognized source of harm. Reveals the lack of evidence that cellular hypoxia is a final common pathway for cell death, and proposes that oxygen itself is responsible for the death of aerobic organisms. Proposes a new management strategy that is “oxygen-protective� rather than “oxygen-promoting.� Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

4.a edicion de uno de los titulos mas vendidos del SLP. Contenido orientado a la practica y actualizado con los ultimos conocimientos, relevante para todos los aspectos medicos y quirurgicos que se aplican en la unidad de cuidados intensivos. El autor es el director of Critical Care, The Miriam Hospital, Providence, RI; Associate Professor, Brown University School of Medicine, Providence, RI.
La nueva edicion incorpora interesantes novedades, como la presentacion a todo color, la inclusion de anadidos digitales actualizados de forma regular por el Dr. Marino, la reescritura de todo el texto y se han anadido 8 nuevos capitulos y un apendice dedicado a la dosificacion de farmacos.

Selected as a Doody's Core Title for 2022! Quick lookup for the most essential info in critical care! Ideal for quick reference at the bedside, The Little ICU Book is a condensed, compact version of The ICU Book , Dr. Marino's best-selling comprehensive intensive care reference .The Little ICU Book zeroes in on only the essentials for the hands-on care of critically ill adult patients. Its fast-access format makes it an indispensible resource for residents as well as busy critical care physicians. Key Features: Apply the latest know-how with comprehensive updates throughout the book. Find the answers you need quickly with a concise outline format and Dr. Marino's accessible, reader-friendly writing style. Grasp visual concepts at a glance through abundant clear, colorful illustrations and tables. Carry it with you everywhere thanks to its portable size.

A fundamental and respected resource book in critical care, The ICU Book, Fourth Edition , continues to provide the current and practical guidance that have made it the best-selling text in critical care. The text addresses both the medical and surgical aspects of critical care, delivering the guidance needed to ensure sound, safe, and effective treatment for patients in intensive care-regardless of the specialty focus of the unit. Traditionally available as a printed textbook, the print version now comes with a completely revamped digital experience, powered by Inkling. Viewable through a browser or as a download to your tablet or smartphone , the digital version includes:" The complete text with optimized navigation A powerful, index-based search function All referenced content is linked throughout for instant access Regular literature and commentary updates integrated into the text The ability to share notes with friends and colleagues NEW to the Fourth Edition Fully rewritten content (including eight new chapters plus a new Appendix on drug dosing) assures readers of only the most up-to-date and practical information availableFull-color format emphasizes clinical anatomy and facilitates visual learning Key Features Problem-based approach teaches critical thinking and mirrors the decision-making process of the intensive care unit Expert perspectives from Dr. Marino help sharpen technique, minimize error, and improve outcomes Reader-friendly format makes essential information easy to locate and apply "Final Word" summaries at the conclusion of each chapter highlight salient points and improve retention of key concepts