This ground-breaking Handbook uniquely focuses on the business of sustainability, offering a fresh insight and practical solutions to the challenges that businesses face in making human activity sustainable. It is organized into four distinctive themes that cut across levels of analysis and illustrate a rich set of solution contexts that will guide future research. The Handbook on the Business of Sustainability offers a comprehensive review of research and empirical evidence on sustainable business, exploring the importance of private sector engagement and implementation. World leading scholars cover the key areas such as organization, execution and the measurement of outcomes and social impact. The insightful case studies also provide critical context and complement the chapters highlighting emerging practices and solutions for the successful application of sustainability initiatives in business. The Handbook will be an invaluable resource for academics, practitioners, and policymakers to reflect on the 'concept and practice' of articulating and strategizing in order to achieve sustainability targets.

This ground-breaking Handbook uniquely focuses on the business of sustainability, offering a fresh insight and practical solutions to the challenges that businesses face in making human activity sustainable. It is organized into four distinctive themes that cut across levels of analysis and illustrate a rich set of solution contexts that will guide future research.   The Handbook on the Business of Sustainability offers a comprehensive review of research and empirical evidence on sustainable business, exploring the importance of private sector engagement and implementation. World leading scholars cover the key areas such as organization, execution and the measurement of outcomes and social impact. The insightful case studies also provide critical context and complement the chapters highlighting emerging practices and solutions for the successful application of sustainability initiatives in business.   The Handbook will be an invaluable resource for academics, practitioners, and policymakers to reflect on the ‘concept and practice’ of articulating and strategizing in order to achieve sustainability targets.

Comprehensive and practical, Pavement Asset Management provides an essential resource for educators, students and those in public agencies and consultancies who are directly responsible for managing road and airport pavements. The book is comprehensive in the integration of activities that go into having safe and cost-effective pavements using the best technologies and management processes available. This is accomplished in seven major parts, and 42 component chapters, ranging from the evolution of pavement management to date requirements to determining needs and priority programming of rehabilitation and maintenance, followed by structural design and economic analysis, implementation of pavement management systems, basic features of working systems and finally by a part on looking ahead. The most current methodologies and practical applications of managing pavements are described in this one-of-a-kind book. Real world up-to-date examples are provided, as well as an extensive list of references for each part.

This affirming, positive, and practical book will better prepare retirees and their families for the changes and challenges of retirement in an uncertain economic, social, and political climate. A Simple Guide to Retirement: How to Make Retirement Work for You is a book for older Americans planning for retirement. It is also for people who have left work before they were ready and are now experiencing anxiety, depression, and/or financial weakness in their new role as retirees. Written to be at once affirming, positive, and practical, the book covers all of the many topics that will help retirees better prepare themselves for a positive, fulfilling, and satisfying retirement-beginning with financial security. These topics include saving for retirement, working part time, staying healthy and fit, dealing with the emotional and financial burden of health care, cultivating optimism, and much more. Case examples and vignettes will help readers apply the principles to their own lives. 10 illustrations

General aspects of nucleic acid uptake by mammalian cells have been the subject of several reviews during the last few years (PAGANO, 1970; BHARGAVA and SHANMUGAM, 1971; DUBES, 1971; RYSER, 1967). These reviews covered methods used for the infection of cells by viral nucleic acids as well as interaction of mammalian cells with non-viral nucleic acids. This article is restricted to a discussion of experiments with poliovirus RNA and focuses special attention on the steps following the uptake of RNA into a cell, aspects that were not discussed in earlier review articles. The fate of input RNA once inside the cell is determined by the host cell but experimental conditions can be chosen to favor the survival of input RNA and the induction of a virus growth cycle by interfering with host-cell meta bolism through events that, in the case of infection with intact virus, might be controlled by viral proteins."

At the end of the last century and the beginning of this century, the prob lems of immunity in lower vertebrates and the influence of environmental temperature attracted attention for the first time (ERNST, 1890; WIDAL and SICARD, 1897; METCHNIKOFF, 1901). However, relatively little work has been done on this subject until recently. The early investigators were chiefly in terested in the immuno-pathological problems. They immunized various species of lower vertebrates essentially with bacterial vaccines; agglutinating, neutralizing and protective antibodies were detected in their blood. The in fluence of environmental temperature on the immune response was investigated, since this subject represented great economical and theoretical importance. Epizootic diseases were observed to occur in relation to the cold season of the year, when the decrease or spontaneous increase of water temperature occurred (SCHAPERCLAUS, 1965; BESSE et al. , 1965; KLONTZ et al. , 1965 WOOD,1966). The immunological deficiency of fish, caused by their natural or experimental stay in cold water, is now evident for both humoral and cellular immunity. In this review we will focus on two points: We shall attempt (1) to explain the mechanism by which the environmental temperature influences the immune resistance of fish to pathogens, (2) to determine the chronological location of this temperature-sensitive stage in the process of antibody formation, and to make some approaches to the general antibody formation mechanism.

This volume is dedicated to the memory of the late Professor WERNER BRAUN, one of the most devoted and active members of the Editorial Board of the Current Topics in Microbiology and Immunology, who passed away, after suffering a heart attack, in November 1972. Dr. WERNER BRAUN was born in Berlin, Germany, on November 16,1914. During his highschool days in Berlin he did research work on problems of genetics as a young guest in the Kaiser-Wilhelm-Institut fur Biologie, in the department of Prof. R. GOLDSCHMIDT. I remember his colourful description of his discussions during this period, while still a teen-ager, with OTTO WAR- BURG. He studied biology and medicine at the University of G6ttingen and received a Ph.D. degree in biology in 1936. In the same year he left Nazi Germany and came to the United States first as a Guest Investigator in Genetics at the University of Michigan at Ann Arbor, and then in Berkeley, where he carried out his work in the Depart- ments of Zoology and of Veterinary Science until 1948. He was engaged during this period in the study of problems concerned with physiological genetics, bacterial variation, immunology and biochemistry.

The expression of many bacterial genes adapts itself in an almost in stantaneous and reversible way to specific environmental changes. More specifically, the concentration of a number of metabolites, a function of the amounts of enzymes involved in their synthesis or degradation, in turn retroacts on the rate of synthesis of these enzymes. The genetic bases for this regulation were established by JACOB and MONOD (1961). These authors also showed how the known elements of these regulatory mechanisms could be connected into a wide variety of circuits endowed with any desired degree of stability, in order to account for essentially irreversible processes like differentiation (MONOD and JACOB, 1961). The general principles used by JACOB and MONOD in their study of negative regulation were extended to positive regulation by ENGLESBERG et al. (1965). An independent approach permitted the discovery of positive controls in temperate bacteriophages (see below, III). Each control operation is mediated by a pair of complementary genetic elements (hereafter called "control cell"): a control gene which produces a l control (or regulator) protein and a control site which is the target for the regulator protein. Negative control means that the control protein (repressor) prevents gene expression. One deals with positive control when the control protein (activator) is necessary for this expression. It has become apparent that, as initially postulated by JACOB and MONOD, control of gene expression operates, at least to a large extent, at the transcriptional level.

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI., 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review."

This is the first new Thai-English dictionary by an American Scholar to appear in over twenty years. It includes many new words and new uses of old words that have entered the language since Wold War II, an it employs the latest official spellin of words (based on the Thai-Thai Government Dictionary of 1950), with some older spellings cross-referenced to the present spelling. Its 20,000 entries are presented in a sinle alphabetical listing: standard vocabulary items, names of people and organizations, place names, and abbreviatiions.
The pronunciation of words is shown in a scientific writing which includes five tones, stress within rhythm groups, and intonation whenever clauses or sentences are cited. The pronunciation guide is not a translation; rather it is the standard pronunciation used by educated speakers in Bangkok, which often differs from the traditional spelling in tone and vowel length.
Levels of usage--vulgar, common, colloquial, elegant, royal, and sacerdotal--are indicated whenever pertinent. Slang terms and idioms are included, and for words that American students find difficult there are grammatical comments and ample examples of usage.

Die Hamatologie hat im vergangenen Jahrzehnt einen erheblichen Zu- wachs an Wissen und Erkenntnissen erfahren. Dies gilt sowohl fur die Physiologie und Pathologie der Zellsysteme auf molekularer Basis, als auch fur die Identifizierung und Beschreibung klinischer Syndrome und definierter Krankheitsbilder. Die Erforschung der ZeIIkinetik hat wesent- lich zum Verstandnis der regulativen Vorgange beigetragen. Am aufregendsten ist zweifellos die Entwicklung im Bereich der Lympho- zyten und Granulozyten mit der Aufdeckung von bisher nicht gekannten Funktionen und Funktionsdefekten. Der Erythrozyt hat weitere Geheim- nisse preisgegeben, vor allem uber die Membran, die Enzyme und das Hamoglobin, sowie uber seine rheologischen Eigenschaften. Die Hamosta- seologie hat die Methoden der Diagnostik erheblich verbessert und auf einigen Gebieten die therapeutischen Moeglichkeiten entscheidend ausge- baut. Die Mehrzahl der Autoren dieses Buches sind Padiater und die Belange des Kindes werden entsprechend berucksichtigt. Die padiatrische Hamatologie hat als Spezialdisziplin ihren festen und berechtigten Platz innerhalb der Padiatrie und der Hamatologie. Von der Hamatologie des Erwachsenen unterscheidet sie sich in vielen Punkten. Das gilt sowohl fur die Normwerte hamatologiseher Daten, als auch fur das Spektrum der Erkrankungen des hamatopoetischen Systems. Insbesondere bietet das Neugeborene viele hamatologische Eigentumlichkeiten, die hier in einem eigenen Kapitel zusammenfassend dargestellt werden. Auch hinsichtlich der Durchfuhrung und Zumutbarkeit diagnostischer und therapeutischer Massnahmen ergeben sich Unterschiede zwischen Kind und Erwachsenem.

Unter Mitarbeit zahlreicher Fachwissenschaftler

Interest in congressional oversight of intelligence has risen again in the 110th Congress, in part because of the House Democratic majority's pledge to enact the remaining recommendations from the U.S. National Commission on Terrorist Attacks upon the United States, commonly known as the 9/11 Commission. Its 2004 conclusions set the stage for reconsideration of the problems affecting Congress' structure in this area. The commission's unanimous report, as detailed in this book, covers many issues, and concludes that congressional oversight of intelligence was "dysfunctional". This book proposes two distinct solutions:(1) creation of a joint committee on intelligence (JCI), modelled after the defunct Joint Committee on Atomic Energy (JCAE), or (2) enhanced status and power for the existing select committees on intelligence, by making them standing committees and granting both authorisation and appropriations power. This book consists of public domain documents which have been located, gathered, combined, reformatted, and enhanced with a subject index, selectively edited and bound to provide easy access.

When Mary R. Haas died in 1996, she left behind several thousand pages of notes and texts in the Creek (Muskogee) language collected in Oklahoma from 1936 to 1940. The majority of the texts come from the unpublished writings of James H. Hill of Eufaula, an especially knowledgeable elder who composed texts for Dr. Haas using the standard Creek alphabet. Twelve other speakers served as sources for dictated texts.