This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, including proteins, enzymes, immunotoxins and secondary metabolites, that target cancer cells and cause tumour regression. The chapters also discuss the critical role of gut microbiota dysbiosis in the pathogenesis of autoimmune disease and in bowel-related diseases. Towards the end, the book explores the role of intestinal microbiota in metabolic health and the pathogenesis of common metabolic disorders. It presents state-of-the-art insights into important aspects of United Nations—Sustainable Developmental Goal 3.

Highlights the impact of Covid 19 on science, health and health care system Includes evolution, structure, and mode of infection by virus as well as strategies to attack various organs in the body. Describes emergence of various strains of virus Emphasis new techniques to detect and control the virus Discusses vaccine development to control the pandemic

The volume is comprehensively covers emerging technologies for health care, various aspects of biomedical research towards understanding of pathophysiology of the diseases, advances in improvement in diagnostic procedures and therapeutic tools, the fundamental role of biomedical research in the development of new medicinal products

Drawing on contributions from more than thirty scholars and experts in the field, this book examines the role of business as an enabler, as an inhibitor, and ultimately as a co-actor in global sustainability transformations expected over the next few decades. The Role of Business in Global Sustainability Transformations employs several theoretical perspectives and provides abundant examples and cases to discuss a variety of emerging concepts, phenomena, and trends shaping business sustainability. Weaving through the chapters, the editors present core tensions and sources of inertia towards transformative change, and acknowledge that envisioning multiple solutions and pathways are possible and desirable. They advocate for the need to align visions, actions and time horizons between policy, society and business in addressing the interlinked socio-ecological challenges that our society currently faces. This book will be an important resource for scholars and professionals working in the field of sustainability and sustainable business, and a vital educational text for students interested in this discipline.

This book explores the unparalleled adversities and strain that the Covid-19 pandemic has caused on the social and economic lives of people. The book allows readers a glimpse into the experiences of death, loss of livelihood, psychological trauma, restrictions on movement and social life, shifts in international relations and effects on big and small industries caused by the pandemic. It focusses on the major shifts caused within communities and highlights how politics, power dynamics and socio-cultural systems have reset and recovered during recent times. The volume also offers suggestions to offset economic hardships the pandemic has caused especially to the poor and marginalised as well as policy changes to help governments and communities to build more resilient economic and health infrastructure and support systems. With interdisciplinary contributions, this book is an essential read for students and researchers of public health, sociology, health economics, healthcare management, development studies, public policy and South Asian studies.

This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.

The volume is comprehensively covers emerging technologies for health care, various aspects of biomedical research towards understanding of pathophysiology of the diseases, advances in improvement in diagnostic procedures and therapeutic tools, the fundamental role of biomedical research in the development of new medicinal products

This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.

Drawing on contributions from more than thirty scholars and experts in the field, this book examines the role of business as an enabler, as an inhibitor, and ultimately as a co-actor in global sustainability transformations expected over the next few decades. The Role of Business in Global Sustainability Transformations employs several theoretical perspectives and provides abundant examples and cases to discuss a variety of emerging concepts, phenomena, and trends shaping business sustainability. Weaving through the chapters, the editors present core tensions and sources of inertia towards transformative change, and acknowledge that envisioning multiple solutions and pathways are possible and desirable. They advocate for the need to align visions, actions and time horizons between policy, society and business in addressing the interlinked socio-ecological challenges that our society currently faces. This book will be an important resource for scholars and professionals working in the field of sustainability and sustainable business, and a vital educational text for students interested in this discipline.

1. This volume looks at various aspects of the challenges that frontline workers and women faced during the Covid-19 pandemic and lockdowns in India and their immense contribution to managing the pandemic. 2. The book will be of interest to departments of public health, health care management, gender studies, public policy making, sociology and economics across UK and USA.

The following important aspects have been addressed: Importance of biodiversity in maintaining ecosystem balance for sustainability. Emerging role of biodiversity as source of important materials, pharmaceuticals, food etc. as such or through genetic manipulations to meet the contemporary and futuristic challenges. Impact of environment degradation on biodiversity and conservation in a changing environment. Conventional and emerging biotechnological techniques to conserve biodiversity.

The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells.  It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.

This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.

This volume elaborately discusses the following issues Concerning environment degradation: anthropogenic and natural factors Climate change, history, causes and threat to abiotic and biotic systems Case studies on impact of climate change and life systems Mitigation and preparedness for future

The volume thus focusses on OMICS (Genomics, proteomics, transcriptomics, metabolonomics) technologies in identifying, characterizing biodiversity Role of molecular techniques for improvement of domestic and non-domestic organisms Animal and alternative model systems (using stem cells, tissue engineering, cell free systems, 3D platforms etc.) for studying life phenomena Genetically Modified Organisms as factories for the products

Flow cytometry has rapidly evolved into a technique for rapid analysis of DNA content, cellular marker expression and electronic sorting of cells of interest for further investigations. Flow cytometers are being extensively used for monitoring of cellular DNA content, phenotype expression, drug transport, calcium flux, proliferation and apoptosis. Phenotypic analysis of marker expression in leukemic cells has become an important tool for diagnostic and therapeutic monitoring of patients. Recent studies have explored the use of flow cytometry for monitoring hormone receptor expression in human solid tumors and for studies in human genomics. Contributions in the current volume are based on presentations made at the First Indo-US workshop on Flow Cytometry in which experts from USA, UK and India discussed applications of flow cytometry in biological and medical research. This book will be of interest to post graduates and researchers in the fields of pathology, cytology, cell biology and molecular biology.

Microbes are the predominant form of life on the planet due to their broad range of adaptation and versatile nutritional behavior. The ability of some microbes to inhabit hostile environment incompatible with most forms of life means that their habitat defines the extent of the biosphere and delineates the barrier between the biosphere and geosphere. The direct and indirect role of microbes that include bacteria, fungi, actinomycetes, viruses, mycoplasma, and protozoans are very much important in development of modern human society for food, drugs, textiles, agriculture, and environment. Furthermore, microorganisms and their enzyme system are responsible for the degradation of various organic matters. Microbes for Sustainable Development and Bioremediation emphasizes the role of microbes for sustainable development of ecosystem. Environmental microbiology role in biogeochemical cycle and bioremediation of environmental waste is major theme, which comprises the following aspects: Bacterial phytoextraction mechanism of heavy metals by native hyperaccumulator plants from complex waste-contaminated site for eco-restoration Role of microbial enzyme for eco-friendly recycling of industrial waste Field-scale remediation of crude oil-contaminated desert soil and treatment technology Microbial technology for metal recovery from e-waste printed circuit board Impact of genomic data on sustainability of ecosystem Methane monooxygenases: their regulations and applications Role of microbes in environmental sustainability and food preservation This book will be directly beneficial to researchers and classroom students, in areas of biotechnology, environmental microbiology, molecular biology, and environmental engineering with specialized collection of cutting-edge knowledge.

This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases.  Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.

The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.

1. Discusses implications of COVID on education, environment, and lifestyle 2. Elucidates life-style transformation strategy to counter COVID 3. Focuses on transformative strategy to overcome COVID impact