Engineers and geologists in the petroleum industry will find Petroleum Related Rock Mechanics, Third Edition, to be a powerful resource in providing a basis for rock mechanical knowledge, which can greatly assist in the understanding of field behavior, design of test programs, and the design of field operations. Not only does this text provide specific applications of rock mechanics used within the petroleum industry, it has a strong focus on basics like drilling, production, and reservoir engineering. Assessment of rock mechanical parameters is covered in depth, as is acoustic wave propagation in rocks, with possible link to 4D seismic as well as log interpretation. Petroleum Related Rock Mechanics, Third Edition, is updated to include new topics such as formation barriers around cased wells, finite element analysis, multicomponent models, acoustic emissions and elliptical holes. It also includes updated and expanded coverage of shale reservoirs, hydraulic fracturing, and carbon capture and sequestration.

The challenge of including youth in the labour market is a problem which many European countries are facing. Examining the transition from education to employment, Youth, Diversity and Employment combines insights from law and the social sciences to link the challenges and specific barriers facing young and vulnerable people today. Based on original research, this book presents ways in which social protection policies in Europe can utilise the synergy between redistribution and regulations to combat economic inactivity and exclusion of young people. Drawing on the experiences of Nordic countries, which represent cases of high theoretical and political relevance, and systematically examining the significance of social regulation on the employment opportunities for young adults, this book develops an original approach to social protection policies. This book focuses on ways to strengthen the demand for the work capacity of European youth, identifying principles which will make the best progress in policy making to assist youth transitions into work. Arguing that gender, ethnicity, and disability are increasingly important factors to consider, chapters reveal how to ensure that the full use of skills that young adults have can be brought to the workforce effectively. This book will be a valuable tool for students and scholars of social policy, sociology, employment and human rights law, and cultural studies, as well as for researchers, who will find the analytical framework and new data useful for future research into youth transitions, policy, and social protection policies. Contributors include: O.M. Arnardottir, O. Backman, R. Halvorsen, M.J. Hotvedt, B. Hvinden, C. Hyggen, V. Jakobsen, K. Jokumsen, L. Kolouh-Soederlund, S. Kuivalainen, T. Lorentzen, S. Niknami, K. Nousianen, T. Olsen, E. OEsterbacka, J.G. Rice, M.A. Schoyen, L. Schroeder, M. Seeleib-Kaiser, T.F. Spreckelsen, J. Tagtstroem, R. Traustadottir, M. Ventegodt, E. Wadensjoe

Engineers and geologists in the petroleum industry will find Petroleum Related Rock Mechanics, 2E, a powerful resource in providing a basis of rock mechanical knowledge - a knowledge which can greatly assist in the understanding of field behavior, design of test programs and the design of field operations. Not only does this text give an introduction to applications of rock mechanics within the petroleum industry, it has a strong focus on basics, drilling, production and reservoir engineering. Assessment of rock mechanical parameters is covered in depth, as is acoustic wave propagation in rocks, with possible link to 4D seismics as well as log interpretation.
* Learn the basic principles behind rock mechanics from leading academic and industry experts
* Quick reference and guide for engineers and geologists working in the field
* Keep informed and up to date on all the latest methods and fundamental concepts

Managing Change in Organisations provides a practical and thorough overview of how effective change can be achieved in organizations. The text is ideal for advanced undergraduates, MBA and postgraduate students on courses in managing change and organisational change. Colin Carnall takes a strategic approach, outlining guidance and techniques for planning and implementing, evaluating and learning from major organizational change. Reviewing traditional and more recent critical theories, he also presents models and frameworks for change that are apt for the complex and fast-moving challenges of contemporary organizations.

Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably. Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.

Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen. In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers."

This volume is a collection of detailed protocols describing state-of-art approaches that will facilitate the understanding of protein homeostasis in plant stress responses and development. Plant Proteostasis: Methods and Protocols is broken into four parts focusing on the study of ubiquitin-dependent post-translational modifications, protocols focused on Ubl post-translational modifications, protein homeostasis, and protocols for the in silico analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Plant Proteostasis: Methods and Protocols aims to address next challenges in agriculture such as precision horticulture.

"Come to us you who thirst for the nature of reality. Come you who yearn for yourself. Come brothers of the breach and broken sisters. Come you who cannot find rest, and who can have no peace." -The Book of Specularis. This is the second book in a trilogy on the Sethian Gnostic tradition of today, and it contains a selection of texts from the Charaxio, the holy book of the organization Sodalitas Sanctum Seth. This collection of modern Sethian writings intends to give new perspectives to those who have stumbled upon an encounter with Metanoia, Our Lady of Unexpected Insight and Perplexity, and thus perceived the shape of the Mystery. Consider this entire book as a projective test. As in the field of psychology, such a test has no meaning in itself: It is you; with your background, opinions, cultural frame of mind and self-understanding that determine what you see, or are shown. As in the previous volume, The Key, it is important to remember that as you read this book, the book is also reading you.

This volume highlights the role of proteostasis in human health and associated disease model systems, reflecting its rising importance which has led to the development of new technologies to obtain insight into underling protein mechanistic events. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Proteostasis: Methods and Protocols aims to become a reference book on proteostasis in human health.

"It is not the time of the creation in itself that disturbs us, nor is it the so-called fall or the time when mankind wandered the world between light and darkness. What disturbs us is what we suspect transpired in the time before time." Magister Amarantus Sodalitas Sanctum Seth Classical Gnosticism points to a path, which is not a path, but rather a path between the paths. It is a story told at the strike of the thirteenth hour on the mystical dial of the wise; from a mental position between truth and falsehood, reality and dream, in a spiritual place that unites all things in a point without a centre. The tradition, to which this book refers is based on Biblical stories of creation, the nature of God, how man came to live on earth, and how we may recapture what humanity lost. This tradition has a systematic enquiring approach to redemption. It thus relies on our own understanding and our own experiences to grasp it. This is the path called Gnosticism; Sethian Gnosticism.

This volume originates from an international conference (Oxford University, 2007). Texts address plaster casts and related themes from antiquity to the present day, and from Egypt to America, Mexico and New Zealand. They are of interest to classical archaeologists, art historians, the history of collecting, curators, conservators, collectors and artists. Articles explore the functions, status and reception of plaster casts in artists' workshops and in private and public collections, as well as hands-on issues, such as the making, trading, display and conservation of plaster casts. Case-studies on artists' use of material and technique include ancient Roman copyists, Renaissance sculptors and painters, Dutch 17th-century workshops, Canova, Boccioni and others. A second theme is the role of plaster casts in the history of collecting from the Renaissance to the present day. Several papers address the dissemination of visual ideas, models and ideals through the medium. Papers on modern and contemporary art illuminate the changing uses and semantic values of plaster casts in this period. Amongst the types of casts discussed are artists' models and final works as well as casts after antiquities, including sculpture, architecture and gems (dactyliothecae). The volume demonstrates the richness of the field, both in terms of the material itself and modern scholarship concerned with it. Conceived as a handbook for students, academics, curators and collectors, the text will form a standard work on the role of plaster casts in the history of Western sculpture.

Mass Spectrometry Data Analysis in Proteomics is an in-depth guide to the theory and practice of analyzing raw mass spectrometry (MS) data in proteomics. As MS is a high throughput technique, proteomic researchers must attend carefully to the associated field of data analysis, and this volume outlines available bioinformatics programs, algorithms, and databases available for MS data analysis. General guidelines for data analysis using search engines such as Mascot, Xtandem, and VEMS are provided, with specific attention to identifying poor quality data and optimizing search parameters. Several different types of MS data are discussed, followed by a description of optimal methods for conversion of raw data into peak lists for input to search engines. Choosing the most accurate and complete databases is emphasized, and a report of available sequence databases is included. Methods for assembling expressed sequence tags (ESTs) into assembled nonredundant databases are provided, along with protocols for further processing the sequences into a format suitable for MS data. Mass Spectrometry Data Analysis in Proteomics describes publicly available applications whenever possible.

This book provides an extensive and comparative account of how governments go about combating poverty and social exclusion in Europe. Contributions to the volume display robust theoretical anchorage to ground the analysis of the complexities of both multi-level and multi-actor governance, while the perspectives and experiences of target groups are also assessed. Research results elicit enduring problematic aspects that are not likely to disappear when full economic recovery takes place and constitute a must-read for all those interested in how to fight social inequality.' - Ana M. Guillen, University of Oviedo, Spain'The authors of this book have succeeded in developing a new and original approach to the study of combating poverty and social exclusion. Using a framework that combines insights from multi-level and network governance theory, the book analyses and compares the governance arrangements that European countries introduced in the context of active inclusion policies, and evaluates why these arrangements work or fail - an ambitious and very relevant project!' - Rik van Berkel, Utrecht School of Governance, the Netherlands Discovering methods to combat poverty and social exclusion has now become a major political challenge in Europe. Combating Poverty in Europe offers an original and timely analysis of how this challenge is met by actors at European, national and subnational levels. Building on a European study comparing Germany, Italy, Poland, Sweden and the UK, this book provides new insights into the processes and mechanisms that promote or hinder interaction between the increasingly multi-layered European system for responding to poverty and social exclusion in EU member states. The contributors present systematic and comparative analyses of social policy design, institutional frameworks and delivery practices from a multi-level governance perspective. Original and diverse, this book will appeal to researchers and scholars in comparative social policy, as well as policy officials in the EU, national government and anti-poverty NGOs. Contributors include: A. Angelin, H. Bennett, D. Clegg, M. Ferrera, R. Halvorsen, B. Hvinden, M. Jessoula, H. Johansson, M. Koch, W. Kozek, J. Kubisa, F. Maino, A. Panican, D. Spannagel, E. Ugreninov, M. Ziele ska

Organizations and societies are facing extreme challenges that require action (IPCC, 2021). The UN's sustainability goals, demographic change, and the green shift are knocking on the door, while traditional education, and ways of leading and managing this development, often fail to keep up. Organizational Change, Leadership and Ethics challenges leadership orthodoxy, assumptions, and myths currently preventing the further development of theory and practice. It encourages intelligent disobedience in support of greater leadership capabilities and capacity in organisations and societies. As such, the book is written for everyone who wants to be MAD - to Make A Difference - students, scholars, and practitioners alike.

The small neck of the aneurysm afforded an easy surgical attack. An ordinary flat silver clip was placed over the sac and tightly compressed obliterated it completely. The clip was flush with the wall of the carotid artery. The sac, lateral to the silver clip, was then picked up with the forceps and thrombosed by the electocautery. Walter Dandy reporting his successful operation of a posterior communicating aneurysm on March 23, 1937. Walter Dandy's patient left the hospital in good health 2 weeks later, and from his report one may gain the impression that the operation was an easy task. Despite continuous developments during the following decades, it was not until the introduction of the operating microscope and microsurgical techniques that surgical treatment was generally accepted. During the microsurgical era surgical results have continued to improve due to diagnostical, neuroanaesthesi ological, and microsurgical refinements, and improved neurointensive care. Endovascular obliteration has become an important treatment alternative but this has not been included in this particular volume. The purpose of the present supplement of the ACTA NEUROCHIRURGICA is to review some of the elements in the neurosurgical management of patients with aneurysmal subarachnoid haemorrhage that are important for a successful outcome. Professor Helge Nornes has been a major force in the development of new techniques and research strategies in this area for a number of years and has recently retired from the National Hospital in Oslo."

The overall theme of this volume is the understanding of human dignity, autonomy, and human rights in health care and social services in modern welfare states, with special reference to the Nordic countries. Focus is put on vulnerable groups such as children, individuals with cognitive impairment or mental illness, and persons with physical disabilities. Experts from different disciplines identify the ethical and legal dilemmas in modern welfare services and describe how basic values and/or rights come in conflict in concrete situations. Of particular interest is how the human rights perspective challenges the policies and regulations of modern welfare states while at the same time providing the overall normative direction for solving ethical, legal, and social conflicts or shortcomings. Although the human rights perspective is the most dominant, insights from philosophy and the social sciences provide both a necessary and fruitful supplement to the legal approach. The volume will be of interest for academics, researchers, and students in the field of health care ethics, human rights, and welfare state policies. It presents a challenging outlook on dilemmas that are characteristic for the modern welfare state in general, and for the Nordic countries in particular, and it will give the reader important insights and references for further studies.

This book offers the first comprehensive, comparative and coherent perspective on parliamentary candidates in contemporary representative democracy. Based on the unique database of the 'Comparative Candidate Survey' project which interrogated parliamentary candidates in more than 30 countries, it fills a significant lacuna by focusing on the thousands of ordinary candidates that participate in national elections. It examines who the candidates are in terms of their socio-demographic background and political career patterns, how they were selected by their parties, what their policy preference are and whether these are congruent to those held by their voters, who they seek to represent and how they intend to do so once elected, and what their visions are on representative democracy and party government. Last but not least, it investigates how they go about reaching out to their potential voters during the election campaign. This book will be of key interest to scholars and students of political parties and party politics, political elites, political communication, political participation, elections, theories of democracy and representation, legislative studies, voting behaviour and more broadly to European politics, as well as to political and policy professionals throughout Europe.

Coordinative Practices in the Building Process: An Ethnographic Perspective presents the principles of the practice-oriented research programmes in the CSCW and HCI domains, explaining and examining the ideas and motivations behind basing technology design on ethnography. The focus throughout is on generating ethnographically informed accounts of the building process and discussing the concepts of cooperative work and coordinative practices in order to frame technology development. Lars Rune Christensen provides an invaluable resource for these communities in this book. Illustrated with real examples from the building process, he reports on the cooperative work and coordinative practices found, allowing readers to feel that they know, from the point of view of the people working in the building process, what it is like to coordinate and do this kind of cooperative work.

In this fully illustrated study, Rune Frederiksen assembles all archaeological and written sources for city walls in the ancient Greek world, and argues that widespread fortification of settlements and towns, usually considered to date from the Classical period, in fact took place much earlier. Frederiksen discusses the types of fortified settlement and the topography of urban fortification, and also the preservation of structures from early settlements. He also presents an architectural history of Greek fortification walls before the Classical period, and makes the intriguing observation that early monumental architecture developed just as much in fortifications as it did in early temples. This underlines the importance of the secular sphere for the development of early communities across the Greek world.