This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans. Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.

This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans.

Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.

This volume is the collection of papers dedicated to Yozo Matsushima on his 60th birthday, which took place on February 11, 1980. A conference in Geometry in honor of Professor Matsushima was held at the University of Notre Dame on May 14 and 15, 1980. Some of the papers in this volume were delivered on this occasion. 0 00 0\ - 15 S. Kobayashi, University 27 R. Ogawa, Loyola 42 P. Ryan, Indiana 1 W. Stoll 2 W. Kaup, University of of California at Berkeley University (Chicago) University at South Bend Tubing en 16 B. Y. Chen, 28 A. Howard 43 M. Kuga, SUNY at 3 G. Shimura, Michigan State University 29 D. Blair, Stony Brook Princeton University 17 G. Ludden, Michigan State University 44 W. Higgins 30 B. Smyth 4 A. Borel, Institute for Michigan State University 45 J. Curry Advanced Study 18 S. Harris, 31 A. Pradhan 46 D. Norris 32 R. Escobales, 5 Y. Matsushima University of Missouri 47 J. Spellecy Canisius College 6 Mrs. Matsushima 19 J. Beem, 48 M. Clancy 7 K. Nomizu, University of Missouri 33 L. Smiley 49 J. Rabinowitz, University 20 D. Collins, 34 C. H. Sung Brown University of Illinois at Chicago Valparaiso University 35 M. Markowitz 8 J. -1. Hano, 50 R. Richardson, Australian Washington University 36 A. Sommese 21 I. Satake, University of National University California at Berkeley 37 A. Vitter, 9 J. Carrell, University of 51 D. Lieberman, 22 H.

This is the proceedings of the IUTAM Symposium on Creep in Structures, held at Nagoya, 3-7 April 2000, which is the 5th one of this series of the IUTAM Symposia organized every then years since 1960. The present proceedings contains 48 innovative papers presented at the 5th Symposium, in which 91 participants from 15 countries participated to consolidate the development of creep research since 1990 and to discuss the new horizons in this fundamental field of applied mechanics in the coming century. the papers contained deal with (1) physical and microstructural process of creep, viscoplasticity and creep damage related to their modeling, (2) elaborated constitutive equations of time-dependent deformation and damage, (3) creep damage and fracture of engineering materials and structures, (4) computational modeling, simulation, analysis and design of structures in creep, and (5) creep of polymers, composites, and heterogeneous materials. This volume is useful for researchers and graduate course students in the relevant fields. The field of optical WDM networks has experienced widespread attention and growth in recent years.