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The present book contains the simple, fast and precise stability
indicating method for the extended release formulation of
Diclofenac sodium using high pressure liquid chromatography
(HPLC).It contains the fundamental concepts to the analytical
chemistry along with the in depth knowledge of HPLC. The objective
of this book was to provide the basic concepts of the analysis by
HPLC to the pharmacy fraternity.
The calibration system provides accurate results with a minimum of
effort. However, a poorly constructed system can waste valuable
instrument and analyst time, and result in poor quality data. This
book will provide a complete set of instructions on how to set up
and evaluate any analytical system, and equipments with an emphasis
on providing the highest quality results with a minimum of effort.
This book provides valuable and practical information that is not
currently available from any other single reference source.
Students/Research scholar will learn: The fundamentals of linear
regression Different options for preparing data What calibration
options are available Why the correlation coefficient is not a good
measure of calibration quality Simple procedures and tests for
evaluating calibration data
Wound is defined simply as the disruption of the cellular and
anatomic continuity of a tissue. Wound may be produced by physical,
chemical, thermal, microbial or immunological insult to the tissue.
Attention should be directed towards discovering an agent, which
will accelerate wound healing either when it is progressing
normally, when it is suppressed by various agents like
corticosteroids, anti neoplastics.or non- steroidal
anti-inflammatory agents. Medical treatment of wound includes
administration of drugs either locally (topical) or systemically
(oral or parenteral) in an attempt to aid wound repair
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Aromatherapy (Paperback)
Vivek Dave, Sarvesh Paliwal, Ankit Anand Kharia
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R1,460
Discovery Miles 14 600
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Ships in 10 - 15 working days
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Aromatherapy is a holistic healing process for thebody and mind
with the use of fragrances. The basisof this therapy lies in the
essential oils containedin plant materials. These can be found in
leaves, flowers, roots, seeds, bark and resin. These oils arehighly
concentrated and when extracted, can either beused in a pure form
or diluted and blended with otheroils to produce the required
strength. Essential oils are medicinal and fragrantand travel
through the blood stream reacting withhormones and enzymes. When
the fragrance is inhaledthe nerve ends in the nose transmit
pleasurablesignals to the brain which reacts to the positivepower
of the fragrant aroma inducing pleasantmemories, restoring
emotional balance and encouragingrelaxation and energisation. Many
of these fragrantoils have antiseptic and antitoxic qualities
andoften act as an antidote to viral infections, inflammations,
aches and pains.
Progeria (also known as "Hutchinson-Gilford progeria syndrome" and
"Hutchinson-Gilford syndrome") is an extremely rare, severe,
genetic condition wherein symptoms resembling aspects of aging are
manifested at an early age. The disease has a very low incidence
and occurs in one per eight million live births.Those born with
progeria typically live about thirteen years, although many have
been known to live into their late teens and early twenties and
rare individuals may even reach their forties. It is a genetic
condition that occurs as a new mutation and is not usually
inherited, although there is a uniquely inheritable form. This is
in contrast to another rare but similar premature aging syndrome,
dyskeratosis congenita (DKC), which is inheritable and will often
be expressed multiple times in a family line.
The aim of this study was to develop a depot formulation of
mirtazapine by w/o emulsification method using chitosan as
controlled release biodegradable polymer. Chitosan microspheres are
used to provide controlled release of mirtazapine and to improve
the bioavailability of degradable substances or enhance the uptake
of hydrophilic substances across the epithelial layers. The effect
of various parameters, such as stirring rate, drug to chitosan
ratio, chitosan concentration and glutaraldehyde concentration on
entrapment efficiency and release study was studied. Stirring speed
affects the size of microspheres, drug to chitosan ratio and
chitosan concentration affects the entrapment efficiency and
release study; glutaraldehyde concentration affects the release of
the drug molecule from the microspheres.
The aim of the work is to evaluate the transdermal potential of
novel vesicular carrier, ethosomes, bearing aceclofenac,
Non-steroidal anti-inflammatory drugs having limited transdermal
permeation. Aceclofenac loaded ethosomal carriers were prepared,
optimized and characterized for vesicular shape and surface
morphology, scanning electronic microscopy, vesicular size,
entrapment efficiency, stability, in- vitro release study.The
formulation having 3% phospholipids content and 40% ethanol showing
the grater entrapment and optimal average vesicle size of
formulation was determine by Malvern Zetamaster & found 0.696 m
and zeta potential of formulation was -6.74 mV. The vesicular
suspension was kept in sealed vials (10ml) at 4 2 C and at room
temperature for 45 days no change is shown in the entrapment
efficiency. The optimized ethosomal formulation showed transdermal
flux (226.1 g/cm /hr) for ethanolic drug solution which is grater
then that of isopropyl alcohol solution (159.0 g/cm /hr). The
result advocates the potential of ethosome formulation to treat
rheumatic disease where facilitated penetration of the drug into
muscle and synovial fluid is desirable.
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