Current Trends in Biomanufacturing focuses on cutting-edge research regarding the design, fabrication, assembly, and measurement of bio-elements into structures, devices, and systems. The field of biomaterial and biomanufacturing is growing exponentially in order to meet the increasing demands of for artificial joints, organs and bone-fixation devices. Rapid advances in the biological sciences and engineering are leading to newer and viable resources, methods and techniques that may providing better quality of life and more affordable health care services. The book covers the broad aspects of biomanufacturing, including: synthesis of biomaterials; implant coating techniques; spark plasma sintering; microwave processing; and cladding, powder metallurgy and electrospinning. The contributors illustrate the recent trends of biomanufacturing, highlighting the important aspects of biomaterial synthesis, and their use as feedstock of fabrication technologies and their characterization, along with their clinical practices. Current Trends in Biomanufacturing updates researchers and scientists the novelties and techniques of the field, as it summarises numerous aspects of biomanufacturing, including synthesis of biomaterials, fabrication of biomedical structures, their in-vivo/ in-vitro, mechanical analysis and associated ISO standards.

Aluminium (Al) based metal matrix composites (MMC) have many potential engineering applications. There has been a critical need for casting of cost-effective MMC. Not much work hitherto been reported for casting of Al based MMC with vacuum moulding. An approach to macro-model the micro hardness and dimensional accuracy for casting of MMC of Al and its alloys have been proposed and applied. Relationship between micro hardness, dimensional accuracy and other parameter has been deduced by using Taguchi's technique L9 orthogonal array (OA). Results indicate that the hardness of MMC developed depends significantly on the component volume, pouring temperature and composition. The comparison with experimental results will also serve as future validation of the model.

The purpose of the present study is to compare investment castings prepared with conventional wax based patterns and Acrylonitrile Butadiene Styrene (ABS) based patterns for bio-medical implant (hip joint). Starting from the identification of component, patterns with three different types of pattern materials (namely: wax, ABS and ABS+wax) were prepared under different experimental conditions. Dimensional measurements were made on the final castings prepared. The results of study highlights that casting with ABS based pattern gives better dimensional accuracy (under given experimental conditions) and component hardness was also acceptable as per application requirement.Final components prepared are acceptable as per ISO standard UNI EN 20286-I (1995). Castings prepared at proposed parametric settings have been studied for functional validation of the parts. Also the study suggested that at proposed parametric settings the process was found to be under statistical control.

In the present research work experimental investigations has been made for development of Al- Al2O3 MMC (metal matrix composite) by combining stir casting and ABS (acrylonitrile butadiene styrene) replica based investment casting. The research started with selection of the standard geometrical component (cube for the present study).The research highlights the effect of reinforcement Al2O3 on mechanical and metallurgical properties of Al based MMC. The input parameters of process are material composition, layer combination and pouring temperature in investment casting. The study highlights the percentage contribution of different input parameters on micro hardness and dimensional accuracy of Al- Al2O3 MMC.

In the present research work effort has been made to study the tribological behavior of dual particle size (DPS) and triple particle size (TPS) of Al2O3 reinforced Al-MMCs (prepared by vacuum moulding process). The study started with selection of the component for industrial application. The study highlights the effect of reinforcement in form of DPS and TPS on mechanical and metallurgical properties of Al- Al2O3 MMCs. The input parameters of process are composition of MMC, vacuum moulding silica sand grain size, vacuum pressure and component volume. The study highlights the percentage contribution of different input parameters on micro hardness, dimensional accuracy and wear properties of Al- Al2O3 MMCs.

In the present research work effort has been made to study the use of Acrylonitrile-Butadine-Styrene (ABS) replicas in investment casting applications.The research start with selection of the component for industrial application with an idea of improvement in accuracy and hardness of the component. The input parameters are production time in Fused Deposition Modeling (FDM), number of layers, layer combination and different materials in investment casting.The study highlights the percentage contribution of different input parameters on micro hardness and dimensional accuracy.

In the present work new replication techniques for a biomedical component having a real 3D shape has been introduced. A dynamic condylar screw (DCS) plate was selected as one of a real 3D biomedical implant for this study. The DCS plate, made of ABS material, was fabricated as a master pattern by fused deposition modelling (FDM) method. After preparation of master pattern mould was fabricated with vacuum moulding process. Finally metal matrix composite (MMC) of Al and Al2O3 has been prepared in vacuum mould for fabrication of DCS plate. This study highlights the replication procedure of DCS plate in detail from the master pattern to a final product with some investigation on mechanical and metallurgical properties.

Modern-day technologies are described by very high-level of computerization, deploying composite and sophisticated machines. The objective behind is to achieve higher productivity and profit in an organization. Therefore it is always desirable to achieve maximum calculated output from every machine in the industry. Reduction in downtime is a step towards getting a maximum output from machines by improving their reliability and availability. In the present research work a systematic approach for Maintenance Planning and Control (as Modified Six Step Method) has been applied on one of the critical Unit, Boiler Section of Thermal Plant as a Case Study. Down time has been reduced by analyzing the failure pattern of critical parts of all types of equipment. The study suggested that with proposed maintenance plan, downtime of a thermal plant can be reduced by 430 hrs over a period of three years and monetary benefit to the organization due to new maintenance policy is of the order of Rs. 18, 00, 00, 000 to 36,00,00,000 INR for the span of three years.

In present work advancement in replication techniques for a biomedical component having a real 3D shape has been introduced. A hip joint was selected as one of a real 3D biomedical implant for this study. A hip joint, made of ABS material, was fabricated as a master pattern by fused deposition modelling (FDM) method. After this mold was made by the deposition of Primary, Secondary and Tertiary coatings with the addition of (1- 2cm in length) nylon fiber of 1.5D as per the Taguchi L9 control log of experimentation.This study outlines complete replication procedure of hip joint in detail from the master pattern to a final product with some investigation on mechanical and metallurgical properties. The results of study highlights that during shell production, fiber modified shells had a much reduced drain time. This gave a higher ceramic retention rate after dipping and led to a thicker coat compared to that produced without fiber addition.