Description
Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique.
.Provides a basic overview of microarray technology and available platforms for those unfamiliar with the technology
.Includes detailed discussion of experimental design and analysis of microarray experiments, giving first-time users valuable information that can be tailored to their own research needs
.Provides discussion of such hot areas as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
Expert author team highlights the utility of the technology using examples from human health and disease--e.g., malaria and cancer diagnostics.

This magnificent and beautiful work includes an extensive and illuminating text paired with an exceptional collection of 646 color photographs and 78 line drawings of the processes involved in forming metal sculpture, as well as contemporary and historic examples. The author describes in detail the two techniques used to form sculpture castings in metal: the lost wax (cire perdu) method, and the modern variant of sand casting. Metal finishing processes on sculptures are explored in detail. One of the remarkable features of the cooperation given by Pangolin Editions, the largest sculpture foundry in Britain, is the presentation of 114 patination recipes, developed over 20 years by Rungwe Kingdon, Director of Pangolin. For a patinator to give away his trade secrets is not just unusual, it is unprecedented. Hurst describes the importance of metal casting in art education, based on his 35 years of experience teaching sculpture students in universities and apprentices in the engineering industry. The book is an important addition to the libraries of art schools and universities as well as professional and amateur sculptors.

This book explores how Artificial Intelligence (AI), by leading to an increase in the autonomy of machines and robots, is offering opportunities for an expanded but uncertain impact on society by humans, machines, and robots. To help readers better understand the relationships between AI, autonomy, humans and machines that will help society reduce human errors in the use of advanced technologies (e.g., airplanes, trains, cars), this edited volume presents a wide selection of the underlying theories, computational models, experimental methods, and field applications. While other literature deals with these topics individually, this book unifies the fields of autonomy and AI, framing them in the broader context of effective integration for human-autonomous machine and robotic systems. The contributions, written by world-class researchers and scientists, elaborate on key research topics at the heart of effective human-machine-robot-systems integration. These topics include, for example, computational support for intelligence analyses; the challenge of verifying today's and future autonomous systems; comparisons between today's machines and autism; implications of human information interaction on artificial intelligence and errors; systems that reason; the autonomy of machines, robots, buildings; and hybrid teams, where hybrid reflects arbitrary combinations of humans, machines and robots. The contributors span the field of autonomous systems research, ranging from industry and academia to government. Given the broad diversity of the research in this book, the editors strove to thoroughly examine the challenges and trends of systems that implement and exhibit AI; the social implications of present and future systems made autonomous with AI; systems with AI seeking to develop trusted relationships among humans, machines, and robots; and the effective human systems integration that must result for trust in these new systems and their applications to increase and to be sustained.

Ceremonies of Innocence updates and collects Steve Russell's commentaries on the contemporary Indian Wars in the United States. Early versions of these essays appeared in Indian Country Today. These essays assume less background in political science, history, and economics than Russell's first book on tribal governance, Sequoyah Rising (Carolina Academic Press 2010). Still, there is much food for thought here not just for tribal voters and officials in tribal government, but also for non-Indians who care about the aggressions against Indian property and self-government that continue in their name.

Winner of the Native Writers Circle of the Americas First Book Award in 2008, Wicked Dew collects Steve Russell's published and previously unpublished poetry under one cover.

The author's eccentric Cousin Ray Sixkiller, who is a Republican, underwent a great deal of turmoil in the 2012 election cycle, rendering him unable to support the Republican candidate. The process was chronicled in the pages of Indian Country Today and it is memorialized here for the edification of those engaged in the ongoing battle for the soul of the Republican Party, or organizing in opposition to the GOP, or standing with most American voters. Most American voters, according to Mr. Sixkiller and Mr. Russell, would sum up the 2012 presidential election: "WTF?"

THIS CHANGES EVERYTHING The world of the modern vampire is rife with cunning deceptions and limitless ambitions. When Jacyn's past is threatened, he makes decisions that jeopardize the present and put the future at risk. Jacyn quickly learns that nothing is what it seemed, and even the closest of people can sometimes be your worst of enemies. What's a vampire to do when he doesn't know who he can trust? How much can Jacyn take before he finally loses his humanity altogether? GET READY TO BE BLOWN AWAY http: //www.jacyns-journey.com

WE EXIST. Beyond the romantic novels, horror films, and popular mythology. We walk amongst you as silent, solemn predators. You might have met one of us in passing. You might work with one of us. You might even be related to one of us and not even know it. Forget what you think you know about vampires. You don't know anything about us. Yet.

More Erotic. More Violent. More Dramatic. More Jacyn. Jacyn is back at his best and worst. Life is turned upside-down when Jacyn tangles with 'The Maestro, ' and life for he and his family will never be the same again. How will Jacyn respond when he learns that everything he does has impacts he couldn't foresee? http: //www.jacyns-journey.c

"Godschild Covenant" is set against a global tribulation caused by the planet Nibiru (Planet X) in 2012. In the midst of this maelstrom, the dubious characters who've lurked in the shadows of Anthony Jarman's life now come forward to propel the story at a breathtaking pace.

Likeable and gifted with psychic abilities, Anthony enjoys political success until his enemies manage to conscript him into the hopeless role of a "releaser." In the midst of this dark passage, destiny recasts his fate when he meets Tanya. Beautiful and dynamic, but sad, she captures Anthony's interest at first sight.

The attraction is mutual, but Tanya cannot yield as easily. The loss of her family still pulls her soul towards lonely tears, away from her pressing need for a new future. As they struggle with their feelings, the ghost of an old love from Anthony's past returns to bond them together in the service of a desperate cause. The Science Behind Godschild Covenant

Godschild Covenant: Return of Nibiru, is rooted in a realistic catastrophe scenario based on the impending flyby of a planet the Sumerians called Nibiru. The Egyptians called it the "Destroyer," and the Mayans warn us that this "Red Comet" will return in 2012.

In researching this book, author Marshall Masters, a former science feature producer for the Cable News Network first researched current solar system observations and then compared those finding with historical accounts in the ancient texts of the Egyptians and Sumerians. Nibiru and the Ancients

Founded in the area of modern day Iraq, Sumer is the oldest known civilization, and the Sumerians wrote extensively about Nibiru. According to their accounts, it orbits our sun every 3600 years. Reddish in color, it is approximately 5 times the size of Earth. Further parallels to these accounts are also found in ancient Egyptian and Mayan records as well.

A similar object was also documented in the Egyptian Texts of the Bronzebook. This 3600-year old work was penned by Egyptian academics following the Exodus. They called it the "Destroyer" and say it caused the Biblical disasters of Noah's Flood and the Ten Plagues of Exodus. They also warn that it will return in the near future.

The Mayans offered the same warning. They called this object the "Red Comet" and told us its return will mark the beginning of the next Mayan Calendar on December 21, 2012. Like the Egyptians, they feared the natural disasters caused by this object and kept a constant vigil on the planet Venus for any sign of its return. Nibiru and 2012

Today, we not only observe Venus, but the entire solar system as well, and what we're seeing is troubling for some. In the last 75 years, the effective energy output of our sun has increased 0.4%, causing the most violent solar activity in recorded history. According to NASA, the next solar cycle will reach its maximum in 2012, and it will be stronger than the last.

Meanwhile, as the global warming debate continues here on Earth, astronomers have observed significant surface warming on Mars and Pluto at levels that could cause an extinction event here on Earth. Additionally, there is a sharp increase in atmospheric perturbations and a host of new X-ray and radio emissions on the other planets in our solar system, as well.