This book provides a systematic coverage of research into medical and biotextiles based on nanomaterials as applicable in healthcare. Divided into three sections, it explains manufacturing, properties, types, and recent developments in nanotechnology based medical textiles backed by case studies. It includes wide range of different clinical applications of biotextiles for healthcare including nanotextile scaffolds, nano-based artificial organs, surgical sutures, enzymatic assisted enhanced biotextiles, tissue engineering or drug delivery system via nanofibers and so forth. Features: Provides strong and broad overview of medical applications in the field of nano and biotextiles. Highlights different approaches, recent research, and emerging innovations. Covers designing or developing nanomaterials based antiviral surface disinfectants with self-cleaning property. Reviews different applications of nano based medical textiles such as deodorize or pH control clothing for hygiene maintenance. Includes the real-life applications based descriptive case studies that offers a diverse range of perspectives. This book is aimed at researchers and graduate students in textile technology and engineering, and medical textiles.

Fundamentals of Nano-Textile Science provides a detailed overview of advanced nano-textiles methods, techniques, and treatments along with explanations of a wide range of applications. This book places emphasis on nanotechnology-based textile enhancements that provide high durability, better affinity, and more functionality in textile material and that overcomes the limitation of conventional processes in the textile industry. The first section of the book deals with the production method of nano-textile fibers. It elaborates how nano-techniques are used for producing textile fiber and discusses various pretreatment processes of textile materials using such methods as nano-scouring, nanobiophotoscouring, nano-bleaching, nano-softening, and nano-surface activation. The second section discusses the wide range of nanofinishing applications to make textile materials antimicrobial, flame retardant, UV-protected, etc. It also discusses different techniques and treatments applied on the surface of the finished product using plasma technology or layer-by-layer deposition techniques. This section also covers nano-based textile applications such as for sports clothing, military textiles, high-performance clothing, or smart wearable high-tech nano-textiles. In the last section, the book concludes with an overview of nanotechnological advancements being used for the management of textile effluents and for removing dyes from wastewater in textile processing, focusing on the health and safety perspective of nano-textiles. The book is written by highly experienced authors in this area and provides an immensely valuable resource for scientific researchers, academics, professionals, engineers, technologists and innovators working on designing and manufacturing textile materials. The volume will be an important resource for those who are looking for innovative production technologies or the latest nanotechnology developments in the design and manufacturing of nano-textile materials. Key features: Provides a detailed theoretical overview of nano-textiles along with novel advanced techniques, methods, treatments for enhanced properties and applications of textiles. Covers relevant techniques applied on the surface of the finished textile product using plasma technology or layer-by-layer deposition techniques Introduces various nanofinishes and applications including for sports clothing, military textiles, high performance clothing or smart wearable high-tech textiles Describes wearable smart nano-textile parameters, types of materials used, applications, and future innovations for prevention of hazards and pandemic diseases Explores innovative methods and treatments for management or removal of textile waste

In this present investigation anti oxidant activity of Achyranthes aspera was evaluate to certify that this methanol extract may be beneficial and may utilize for vivo assessment in different kind of biological activity such as anti asthmatic, antimicrobial, antiulcer activity because ulcer is formed due to stress, alcohol consumption.

The aim of the present study was to enhance the dissolution and bioavailability of aceclofenac by using a natural biodegradable polymer, chitosan.Recently, natural polymers such as polysaccharides and proteins have received much attention in the pharmaceutical field owing to their good biocompatibility and biodegradability. Among polysaccharides, chitosan has been considered to be one of the most promising biopolymer for drug delivery systems. The approach was to precipitate chitosan over drug crystals in the presence of a salting out agent sodium citrate, along with micronization of drug crystals.If this process can be scaled-up to manufacturing level, this technique has the potential to develop into an invaluable technology in future. OBJECTIVE To carry out the preformulation studies. Preparation of aceclofenac chitosan formulations. Physicochemical characterization of the prepared formulations. To carry out in vitro drug release studies. To assess stability of the developed formulation. To carry out pharmacodynamic and pharmacokinetic studies in animals.

Wound is defined simply as the disruption of the cellular and anatomic continuity of a tissue. Wound may be produced by physical, chemical, thermal, microbial or immunological insult to the tissue. Attention should be directed towards discovering an agent, which will accelerate wound healing either when it is progressing normally, when it is suppressed by various agents like corticosteroids, anti neoplastics.or non- steroidal anti-inflammatory agents. Medical treatment of wound includes administration of drugs either locally (topical) or systemically (oral or parenteral) in an attempt to aid wound repair

Sustained release of macromolecular drugs from polymeric matrices has received increasing attention in recent years. Vaccines that are required to be given in multiple divided doses are not efficacious if only one dose is given without boosting. In order to be effective, most vaccines require two or three booster doses after primary immunization. Therefore, the conversion of multiple dose vaccines into single dose vaccines may represent an important advance. Among the various tentative for improving the administration of proteins, the microencapsulation into biodegradable polymers represents a practical and promising approachControlled drug delivery technology using biodegradable polymers as carriers represents one of the most rapidly advancing area of science.

Aromatherapy is a holistic healing process for thebody and mind with the use of fragrances. The basisof this therapy lies in the essential oils containedin plant materials. These can be found in leaves, flowers, roots, seeds, bark and resin. These oils arehighly concentrated and when extracted, can either beused in a pure form or diluted and blended with otheroils to produce the required strength. Essential oils are medicinal and fragrantand travel through the blood stream reacting withhormones and enzymes. When the fragrance is inhaledthe nerve ends in the nose transmit pleasurablesignals to the brain which reacts to the positivepower of the fragrant aroma inducing pleasantmemories, restoring emotional balance and encouragingrelaxation and energisation. Many of these fragrantoils have antiseptic and antitoxic qualities andoften act as an antidote to viral infections, inflammations, aches and pains.

Progeria (also known as "Hutchinson-Gilford progeria syndrome" and "Hutchinson-Gilford syndrome") is an extremely rare, severe, genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The disease has a very low incidence and occurs in one per eight million live births.Those born with progeria typically live about thirteen years, although many have been known to live into their late teens and early twenties and rare individuals may even reach their forties. It is a genetic condition that occurs as a new mutation and is not usually inherited, although there is a uniquely inheritable form. This is in contrast to another rare but similar premature aging syndrome, dyskeratosis congenita (DKC), which is inheritable and will often be expressed multiple times in a family line.

The aim of this study was to develop a depot formulation of mirtazapine by w/o emulsification method using chitosan as controlled release biodegradable polymer. Chitosan microspheres are used to provide controlled release of mirtazapine and to improve the bioavailability of degradable substances or enhance the uptake of hydrophilic substances across the epithelial layers. The effect of various parameters, such as stirring rate, drug to chitosan ratio, chitosan concentration and glutaraldehyde concentration on entrapment efficiency and release study was studied. Stirring speed affects the size of microspheres, drug to chitosan ratio and chitosan concentration affects the entrapment efficiency and release study; glutaraldehyde concentration affects the release of the drug molecule from the microspheres.

The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a "self eroding matrix system" made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.

The aim of the work is to evaluate the transdermal potential of novel vesicular carrier, ethosomes, bearing aceclofenac, Non-steroidal anti-inflammatory drugs having limited transdermal permeation. Aceclofenac loaded ethosomal carriers were prepared, optimized and characterized for vesicular shape and surface morphology, scanning electronic microscopy, vesicular size, entrapment efficiency, stability, in- vitro release study.The formulation having 3% phospholipids content and 40% ethanol showing the grater entrapment and optimal average vesicle size of formulation was determine by Malvern Zetamaster & found 0.696 m and zeta potential of formulation was -6.74 mV. The vesicular suspension was kept in sealed vials (10ml) at 4 2 C and at room temperature for 45 days no change is shown in the entrapment efficiency. The optimized ethosomal formulation showed transdermal flux (226.1 g/cm /hr) for ethanolic drug solution which is grater then that of isopropyl alcohol solution (159.0 g/cm /hr). The result advocates the potential of ethosome formulation to treat rheumatic disease where facilitated penetration of the drug into muscle and synovial fluid is desirable.