Winner of the Pulitzer Prize, Tennessee Williams's A Streetcar Named Desire is the tale of a catastrophic confrontation between fantasy and reality, embodied in the characters of Blanche DuBois and Stanley Kowalski. This Penguin Modern Classics edition includes an introduction by Arthur Miller. 'I have always depended on the kindness of strangers' Fading southern belle Blanche DuBois is adrift in the modern world. When she arrives to stay with her sister Stella in a crowded, boisterous corner of New Orleans, her delusions of grandeur bring her into conflict with Stella's crude, brutish husband Stanley Kowalski. Eventually their violent collision course causes Blanche's fragile sense of identity to crumble, threatening to destroy her sanity and her one chance of happiness. Tennessee Williams's steamy and shocking landmark drama, recreated as the immortal film starring Marlon Brando, is one of the most influential plays of the twentieth century. Tennessee Williams (1911-1983) was born in Columbus, Mississippi. When his father, a travelling salesman, moved with his family to St Louis some years later, both he and his sister found it impossible to settle down to city life. He entered college during the Depression and left after a couple of years to take a clerical job in a shoe company. He stayed there for two years, spending the evenings writing. He received a Rockefeller Fellowship in 1940 for his play Battle of Angels, and he won the Pulitzer Prize in 1948 and 1955. Among his many other plays Penguin have published The Glass Menagerie (1944), The Rose Tattoo (1951), Cat on a Hot Tin Roof (1955), Sweet Bird of Youth (1959), The Night of the Iguana (1961), and Small Craft Warnings (1972). If you enjoyed A Streetcar Named Desire, you might like The Glass Menagerie, also available in Penguin Modern Classics. 'Lyrical and poetic and human and heartbreaking and memorable and funny' Francis Ford Coppola, director of The Godfather 'One of the greatest American plays' Observer

In recent years, interest in proteins has surged. This resurgence has been driven by the expansion of the post-genomic era when structural genomics and proteomics require new techniques in protein chemistry and new applications of older techniques. Protein chemistry methods are used by nearly every discipline of biomedical research. Many techniques have been used in less traditional ways with exciting results. Modern Protein Chemistry: Practical Aspects describes the practical side of advanced techniques in protein chemistry. The book gives researchers an excellent "cost-benefit" analysis of these techniques. The contributors have been selected for their prominence in their specific fields and because they run laboratories that actively collaborate with other scientists. Researchers and practitioners, both beginners and experienced, who are looking for new ideas and who are interested in applying these more advanced methods will be assisted in their work by these commentaries. This guide provides hands-on information to complement theoretical understanding. The theory behind these methods can be found in existing books and in the original literature. However, no other guide will help you make a practical evaluation of these methods and their value to your work.

In recent years, interest in proteins has surged. This resurgence has been driven by the expansion of the post-genomic era when structural genomics and proteomics require new techniques in protein chemistry and new applications of older techniques. Protein chemistry methods are used by nearly every discipline of biomedical research. Many techniques have been used in less traditional ways with exciting results. Modern Protein Chemistry: Practical Aspects describes the practical side of advanced techniques in protein chemistry. The book gives researchers an excellent "cost-benefit" analysis of these techniques.

The contributors have been selected for their prominence in their specific fields and because they run laboratories that actively collaborate with other scientists. Researchers and practitioners, both beginners and experienced, who are looking for new ideas and who are interested in applying these more advanced methods will be assisted in their work by these commentaries.

This guide provides hands-on information to complement theoretical understanding. The theory behind these methods can be found in existing books and in the original literature. However, no other guide will help you make a practical evaluation of these methods and their value to your work.

This volume provides an overview of a variety of approaches to biological image analysis, which allow for the study of living organisms at all levels of complexity and organization. These organisms range from individual macromolecules to subcellular and cellular volumes, tissues and microbial communities. Such a "systems biology" understanding of life requires the combination of a variety of imaging techniques, and with it an in-depth understanding of their respective strengths and limitations, as well as their intersection with other techniques. Howard, Brown, and Auer show us that the integration of these imaging techniques will allow us to overcome the reductionist approach to biology that dominated the twentieth century, which was aimed at examining the physical and chemical properties of life's constituents, one macromolecule at a time. However, while based on the laws of physics and chemistry, life is not simply a set of chemical reactions and physical forces; it features an exquisite spatiotemporal organization that allows an inconceivably large number of chemical processes to coexist, refined by billions of years of evolutionary experimentation.
And yet, many fundamental questions remain largely unanswered; Imaging Life argues that we are just now beginning to address the spatiotemporal organizational component of living processes. "Imaging" is needed in order to reveal the spatiotemporal relationships between components, and thus to understand organizational guiding principles of living systems. Only through imaging will we be able to decipher the mechanisms and the marvelous organization that enable and sustain the mystery of life. Imaging Life shows us how biology is beginning to do just that.

Tennessee Williams's evocation of loneliness and lost love, The Glass Menagerie is one of his most powerful and moving plays. This Penguin Modern Classics edition includes a new introduction by Robert Bray. Abandoned by her husband, Amanda Wingfield comforts herself with recollections of her earlier, more gracious life in Blue Mountain when she was pursued by 'gentleman callers'. Her son Tom, a poet with a job in a warehouse, longs for adventure and escape from his mother's suffocating embrace, while Laura, her shy crippled daughter, has her glass menagerie and her memories. Amanda is desperate to find her daughter a husband, but when the long-awaited gentleman caller does arrive, Laura's romantic illusions are crushed. Tennessee Williams (1911-1983) was born in Columbus, Mississippi. When his father, a travelling salesman, moved with his family to St Louis some years later, both he and his sister found it impossible to settle down to city life. He entered college during the Depression and left after a couple of years to take a clerical job in a shoe company. He stayed there for two years, spending the evenings writing. He received a Rockefeller Fellowship in 1940 for his play Battle of Angels, and he won the Pulitzer Prize in 1948 and 1955. Among his many other plays Penguin have published The Glass Menagerie (1944), A Streetcar Named Desire (1947), The Rose Tattoo (1951), Cat on a Hot Tin Roof (1955), Sweet Bird of Youth (1959), The Night of the Iguana (1961), and Small Craft Warnings (1972). If you enjoyed The Glass Menagerie, you might like Cat on a Hot Tin Roof, also available in Penguin Modern Classics. 'Tennessee Williams will live as long as drama itself' Peter Shaffer, author of Equus