Often being vastly underrated the human sense of smell plays an essential role in our life, e.g. in food acceptance, fragrance appreciation, and as a warning device for spoiled food, toxic gases and the presence of fire. The book provides a multidisciplinary up-to-date review of the structure and function of the sense of smell and of how it is influenced by the environment and diseases. It is divided into the following 5 sections: - Anatomy, Physiology and Chemistry - Measurement of OlfactoryResponses - Development and Senescense - Basic Characteristics of Human Olfaction - Clinical and Health Aspects of Olfaction.

The impacts of specifically experienced external and internal environments upon phylogenetically established pathways of ontogenetic development seem to be responsible for the intra-species variation of organisms. Therefore normal function, as well as disorders of sensory systems, can often be better understood by considering the principles of ontogenetic maturation and the time schedule of environmental influences during that period. Sensory organs and systems have long been considered to be hereditally determin ed for their analysis of the environment. However, it is becoming more and more clear that their specificity depends also upon the sequence and nature of environ mental impacts, impacts during highly sensitive periods of postnatal life being most effective. The present book, using an interdisciplinary approach, has brought together various descriptions of developmental processes for one of the phylogenetically oldest sensory analytical circuits, the olfactory system. Although investigations of a wide range of vertebrates are included, from marsupials to man, the main attention was given to rodents, the most frequently used experimental animal in this fields of research. Authors have been asked for reviews and original considerations on the rationales of developmental principles in the olfactory system, and wherever appropriate to highlight its uniqueness or similarities with other parts of the nervous system. Authors were also asked to consider future needs of research in their fields, to describe their own approaches in this context, and to outline general horizons of neurodevelopmental research."