This book provides a dynamic simulation model based on input-output table. The model includes an objective function, i.e. maximizing economic and social development and three sub-models, including economic growth model, pollutant emission model and energy balance model. The data of 2012 is selected as the base period data. The haze control policy of Hebei Province is written into the model as an exogenous variable. Reducing the total PM2.5 emissions is an environmental constraint, which is used to eliminate the impact of natural factors on environmental quality. Lingo software is used to simulate this model. By comparing the socio-economic impacts in different scenarios, this book found the most effective policy combination of haze governance. Comprehensive haze governance policy recommendations provide experience for other regions of China and other developing countries. In this book, the dynamic simulation model of haze governance also provides a reference to other environmental policy simulations. This book is divided into five parts. The first part is an introduction. This paper mainly introduces the research background, research status at home and abroad, the purpose and significance of the study, the content and methods of the study, the key scientific problems to be solved and the expected results. In the second part, the current situation and existing problems of economic, social, energy and environment development in the study area are analyzed in detail. In the third part, a comprehensive evaluation model of dynamic optimization of haze control policy is constructed. The fourth part carries on the simulation experiment, and carries on the analysis to the experimental result. The fifth part puts forward the policy suggestions to realize the economic, social, energy and environmental development of Hebei Province. In this book, we have some understandings about haze governance. From the perspective of policy effect, the policy effects of subsidy for soil and water conservation, subsidy for development and utilization of clean energy, subsidy for new energy vehicles, motor vehicle restriction and subsidy for introduction of PM2.5 treatment technology are decreasing. Comprehensive policy can better achieve the goal of sustainable development of economy, energy and environment than single policy, and the effect of "source governance" policy is better than that of "end governance" policy.

1. This title uses the balance sheet approach and macro-financial linkage analysis to conduct a comprehensive analysis of the trends within China’s macroeconomy in 2020. 2. This is one of the first works to examine macroeconomy of China under the backdrop of the COVID-19 pandemic. 3. This title is one of the latest works of Zhang Xiaojing, who is is the recipient of many prestigious awards such as Sun Yefang Financial Innovation Prize for 2015, and Sun Yefang Economics Prize for 2005 and 2007.

1. This title uses the balance sheet approach and macro-financial linkage analysis to conduct a comprehensive analysis of the trends within China's macroeconomy in 2020. 2. This is one of the first works to examine macroeconomy of China under the backdrop of the COVID-19 pandemic. 3. This title is one of the latest works of Zhang Xiaojing, who is is the recipient of many prestigious awards such as Sun Yefang Financial Innovation Prize for 2015, and Sun Yefang Economics Prize for 2005 and 2007.

Several medical options in palliative care can have complex moral, religious, cultural, medical and legal issues. These treatment options, such as assisted suicide, rehydration, parenteral nutrition and cardiopulmonary resuscitation have been heavily debated in the literature. Physician-assisted suicide is a controversial topic for debate, with growing pressure from advocacy groups for legalisation in regions that have yet to decide. Currently, there is substantial opposition from concerned medical professionals. However, a school of medical professionals acknowledges that physician-assisted suicide may have a role in terminal care. The debate over the use of artificial nutrition and hydration (ANH) in terminal illness is also contentious despite extensive ethical and empirical research. Advocates for and against ANH both agree that the most compassionate and humane option for patients near the end of life is hospice and/or palliative care. However, many of those who support ANH do not seem to appreciate that the standard palliative practice is to avoid the use of ANH in almost all instances. These topics remain heavily disputed in the medical community. In formulating a satisfactory answer, we need to remind ourselves that we cannot generalise a treatment as a correct or incorrect option. Rather, we need to consider each case individually, weigh the risks and benefits of each treatment, and individually consider treatment options in a multidisciplinary care model.

Many cancer patients experience a variety of distressing symptoms, adversely affecting their functional status and quality of life (QOL). Subjective symptoms such as pain, fatigue and depression are common among cancer patients, with approximately 33-55% of cancer patients experiencing pain during the course of their illness. Previous literature commonly examined a single symptom and its effect on patients' functional status and QOL, but patients often experience multiple symptoms simultaneously. Since individual symptoms are often associated with decreased QOL, the assumption that symptom clusters might have a greater effect on QOL is logical. The coexistence of symptoms provides an insight into the importance of assessing clusters of symptoms rather than focusing on individual symptoms. Although the focus of single symptoms has advanced the understanding of those particular symptoms, it may not be as helpful to health care professionals in guiding practice when patients present several concurrent symptoms. It is important for clinicians to address and ultimately treat all concurrent symptoms. Symptom cluster research will help our understanding and treatment of multiple symptoms.

In Canada over the past fifteen years, there has been a 39% rise in new cancer patients, necessitating the expansion of current oncological facilities. The population is getting older and larger, which in turn is translating into more cases of cancer. Other reports projecting cancer growth across different countries found similar results. With the prevalence of cancer expected to increase in the future, it is important to properly allocate resources towards cancer research to better serve the population. Patients with cancer continue to live longer; as such, more elderly individuals will live with cancer. In fact, cancer has been classified as a chronic illness alongside diabetes, hypertension, and heart disease. This may translate to an increased demand for oncologists, specialist-trained nurses, diagnostic services, cancer centres, cancer therapies and palliative care. More importantly, this will translate to an increased necessity for cancer research to decrease the mortality and morbidity associated with cancer while improving the quality of care.

With effective systemic therapy and comprehensive supportive care, patients with metastases can live longer. Breast cancer patients with only or predominantly bone metastases have a median survival of 2.3 years following diagnosis, while metastatic prostate cancer patients have a median survival time of 11.3 months. With recent advances in research, the overall survivorship of metastatic patients has increased. The improved quality of care for metastatic cancer patients has resulted in longer survivorship. Living longer can lead to a higher chance of development for skeletal-related events (SREs), which are defined as either spinal cord compression, hypercalcemia, pathological fractures or a need for palliative radiation therapy or surgery for bone pain. To try to reduce pathological fractures, it is important to detect impending fractures earlier and to administer prophylactic surgery as needed. Longer survivorship also allows time for the development of brain metastases. Recent advances incorporating stereotactic radiosurgery (SRS) have been favored over conventional whole-brain radiation therapy (WBRT) in the preservation of neurocognitive functions and survival benefit in patients less than 50 years of age. Multidisciplinary clinics for brain metastases are again desirable with the joint input of the radiation oncologists and neurosurgeons.

This book provides a dynamic simulation model based on input-output table. The model includes an objective function, i.e. maximizing economic and social development and three sub-models, including economic growth model, pollutant emission model and energy balance model. The data of 2012 is selected as the base period data. The haze control policy of Hebei Province is written into the model as an exogenous variable. Reducing the total PM2.5 emissions is an environmental constraint, which is used to eliminate the impact of natural factors on environmental quality. Lingo software is used to simulate this model. By comparing the socio-economic impacts in different scenarios, this book found the most effective policy combination of haze governance. Comprehensive haze governance policy recommendations provide experience for other regions of China and other developing countries. In this book, the dynamic simulation model of haze governance also provides a reference to other environmental policy simulations. This book is divided into five parts. The first part is an introduction. This paper mainly introduces the research background, research status at home and abroad, the purpose and significance of the study, the content and methods of the study, the key scientific problems to be solved and the expected results. In the second part, the current situation and existing problems of economic, social, energy and environment development in the study area are analyzed in detail. In the third part, a comprehensive evaluation model of dynamic optimization of haze control policy is constructed. The fourth part carries on the simulation experiment, and carries on the analysis to the experimental result. The fifth part puts forward the policy suggestions to realize the economic, social, energy and environmental development of Hebei Province. In this book, we have some understandings about haze governance. From the perspective of policy effect, the policy effects of subsidy for soil and water conservation, subsidy for development and utilization of clean energy, subsidy for new energy vehicles, motor vehicle restriction and subsidy for introduction of PM2.5 treatment technology are decreasing. Comprehensive policy can better achieve the goal of sustainable development of economy, energy and environment than single policy, and the effect of "source governance" policy is better than that of "end governance" policy.

In early stages of cancer, patients are often presented with treatment options and encouraged to have shared treatment decisions with their oncologists. Shared decision making becomes particularly important, as several treatment options with different possible outcomes and adverse events exist. For example, women with early breast cancer are counseled on the options of mastectomy versus lumpectomy and radiation. The same principle should also apply in late stages of cancer, where cure is usually not possible in patients with widespread metastases. In these cases, the aim of treatment should be to relieve symptoms and suffering. Improving quality of life (QOL) rather than tumor control takes priority in palliative care. QOL has also been identified as an important endpoint for new cancer drugs, as determined by the Food and Drug Administration (FDA); as such, cancer drug approval can be based on improvement of QOL. The use of patient-reported QOL instrument tools help clinicians determine if certain treatments improve QOL. The research of palliative interventions should have QOL assessment to assist clinicians, patients and their family members in shared decision making.