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Cancer - Bone Metastases, CNS Metastases & Pathological Fractures (Hardcover)
Loot Price: R4,589
Discovery Miles 45 890
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Cancer - Bone Metastases, CNS Metastases & Pathological Fractures (Hardcover)
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With effective systemic therapy and comprehensive supportive care,
patients with metastases can live longer. Breast cancer patients
with only or predominantly bone metastases have a median survival
of 2.3 years following diagnosis, while metastatic prostate cancer
patients have a median survival time of 11.3 months. With recent
advances in research, the overall survivorship of metastatic
patients has increased. The improved quality of care for metastatic
cancer patients has resulted in longer survivorship. Living longer
can lead to a higher chance of development for skeletal-related
events (SREs), which are defined as either spinal cord compression,
hypercalcemia, pathological fractures or a need for palliative
radiation therapy or surgery for bone pain. To try to reduce
pathological fractures, it is important to detect impending
fractures earlier and to administer prophylactic surgery as needed.
Longer survivorship also allows time for the development of brain
metastases. Recent advances incorporating stereotactic radiosurgery
(SRS) have been favored over conventional whole-brain radiation
therapy (WBRT) in the preservation of neurocognitive functions and
survival benefit in patients less than 50 years of age.
Multidisciplinary clinics for brain metastases are again desirable
with the joint input of the radiation oncologists and
neurosurgeons.
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