This text provides a comprehensive review and expertise on various interventional cancer pain procedures. The first part of the text addresses the lack of consistency seen in the literature regarding interventional treatment options for specific cancer pain syndromes. Initially, it discusses primary cancer and treatment-related cancer pain syndromes that physicians may encounter when managing cancer patients. The implementation of paradigms that can be used in treating specific groups of cancer such as breast cancer, follows. The remainder of the text delves into a more common approach to addressing interventional cancer pain medicine. After discussing interventional options that are commonly employed by physicians, the text investigates how surgeons may address some of the more severe pain syndromes, and covers the most important interventional available for our patients, intrathecal drug delivery. Chapters also cover radiologic options in targeted neurolysis and ablative techniques, specifically for bone metastasis, rehabilitation to address patients' quality of life and function, and integrative and psychological therapies. Essentials of Interventional Cancer Pain Management globally assesses and addresses patients' needs throughout the cancer journey. Written by experts in the field, and packed with copious tables, figures, and flow charts, this book is a must-have for pain physicians, residents, and fellows.

What we have sought in this collection of 'Top Tips' (how to do it) and 'Caveats' (how not to do it) is to compile the Pearls of Wisdom that have been passed down from colleagues all around the world. These are the small details of practice which we have come to rely on when the going gets tough. Most of them are too obscure or even downright strange to make the main stream text books. Many are not 'evidence based'. We are not seeking to rival the Cochrane database but do believe that, worthy as the scholarly collection may be, there is still a place in medicine for skill, artistry and individualism. We are merely trying to spread the word slightly further and perhaps add another string to a few bows, for those times when the available options seem a little limited.

Recent Advances in Anaesthesia and Intensive Care, volume 23 is the latest volume in this very successful and long-established series (previously entitled Recent Advances in Anaesthesia and Analgesia) to present a collection of cutting-edge topics for anaesthetists. It has been compiled by some of the world's leading authorities in their subjects and builds on the successful formula of the previous volumes. As the title suggests, these latest volumes have increased input from the field of intensive care, and the emphasis remains on producing articles of high quality and interest to the reader while providing exceptional value for money. This volume is recommended reading for trainee and practising anaesthetists and intensivists at all levels of experience.

This book traces the global chemical history of cannabidiol (CBD), which is a compound that originates partially from hemp (the fiber), marijuana (the popularized term for medicinal/recreational use), and cannabis (the species sativa). It also argues about the position that CBD is in today and the heritage established by chemists over the course of its development. Each term associated with the plant spans centuries of development and cross-culturally became an object of cultivation and commerce. Humans have explored cannabis' complex chemical possibilities with the hope that it would offer pain relief or some type of mind-numbing portal to other existences. As such the trio and their many incarnations have been and will continue to be an integral part of the past, the present, and the future. Known as cannabis compound cannabidiol (CBD), a non-psychoactive component of the drug, it is one of some 100-plus known cannabinoids; offshoots of the original plant that are isolated and, in some cases, chemically altered. Just as with any supposed pharmaceutical marvel, chemists are at the center of this narrative. In order to understand its historical roots, central to CBD's discovery was the efforts of scientists who worked in separate eras and regions. These included, Americans Roger Adams and Allyn Howlett, and the Bulgarian-born Israeli chemist Raphael Mechoulam, along with a throng of others. They influenced a generation of students and changed the face of cannabis research into the 21st century. What does its history tell us about the future of chemical products like CBD? This brief will explore the chemical heritage that formed across a complicated nexus of global events. These are the bonds that tie.

Clinical decisions in modern medical practice are increasingly influenced by ethical and legal issues, but few doctors have been formally trained in medical law and ethics, and are unsure of potential sources of accessible information, which leaves them exposed to public criticism and the threat of legal action. Perioperative medicine and critical care are, by their very nature, subjects in which issues of autonomy, dignity, consent, confidentiality, medical research, life and death decision making, and the rationing of health care resources are ever-present. This book provides a straightforward but comprehensive one-stop reference and should be essential reading for all medical and allied health care professionals who encounter ethicolegal problems during their management of patients.

The proportion of the population of octogenarians and elderly patients presenting for intensive care is rapidly increasing thus exacerbating the need to modify our critical care management to cater for this patient group. This book will provide practical guidance on all issues related to the critical care of elderly patients, incorporating physiological and epidemiological information, clinical guidance, ethical and end-of-life issues and advice about optimal use of drugs and new technologies. Complications of polypharmacy, high-risk surgery and increased recovery times are also discussed. Chapters are concise, each including a list of key points and summary of available data, making this a quick reference for experienced consultants, as well as a useful resource for trainees preparing for exams.

Multiple-choice questions (MCQs) are used by many examination boards as a way of testing a broad spectrum of knowledge in an easily administered and unbiased way. They form a critical part of both the Primary and Final FRCA (Fellowship of the Royal College of Anaesthetists) examinations. This book builds on GMM's established reputation in publishing for postgraduate anaesthetic exams and particularly for the MCQ component of the exams (e.g. the QBase book and CD-ROM series and accompanying textbooks). Six 90-question examinations, and a 30-question sample examination are presented, offering 570 individual questions with detailed model answers and making this book a comprehensive self-learning tool, especially when used in conjun ction with other key texts such as Fundamentals of Anaesthesia.

Experiential evidence shows that pain is associated with common meanings. These include a meaning of threat or danger, which is experienced as immediately distressing or unpleasant; cognitive meanings, which are focused on the long-term consequences of having chronic pain; and existential meanings such as hopelessness, which are more about the person with chronic pain than the pain itself. This interdisciplinary book - the second in the three-volume Meanings of Pain series edited by Dr Simon van Rysewyk - aims to better understand pain by describing experiences of pain and the meanings these experiences hold for the people living through them. The lived experiences of pain described here involve various types of chronic pain, including spinal pain, labour pain, rheumatic pain, diabetic peripheral neuropathic pain, fibromyalgia, complex regional pain syndrome, endometriosis-associated pain, and cancer-related pain. Two chapters provide narrative descriptions of pain, recounted and interpreted by people with pain. Language is important to understanding the meaning of pain since it is the primary tool human beings use to manipulate meaning. As discussed in the book, linguistic meaning may hold clues to understanding some pain-related experiences, including the stigmatisation of people with pain, the dynamics of patient-clinician communication, and other issues, such as relationships between pain, public policy and the law, and attempts to develop a taxonomy of pain that is meaningful for patients. Clinical implications are described in each chapter. This book is intended for people with pain, their family members or caregivers, clinicians, researchers, advocates, and policy makers.

This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention.

Tracheostomy: A Multi-Professional Handbook is written by a multidisciplinary team of authors to give a unique perspective of this increasingly widely-used technique and which will support research-based care and management and deliver patient-focused rehabilitation. It covers everything from the basics of tracheostomy, through the indications for tracheostomy and all aspects of pre-, peri- and postoperative care of the patient. The latter forms a large part of the book, and focuses on issues of importance to a broad spectrum of healthcare professionals, such as how patient communication is affected by the technique and how optimum wound care during tracheostomy is best achieved, as well as the practical aspects and problems encountered with speech, swallowing and general rehabilitation, nutrition, weaning and decannulation, long-term tracheostomy, tracheostomy in children, and an important chapter on emergency tracheostomy techniques.

This issue of Anesthesiology Clinics, guest edited by Drs. Jeffrey Kirsch and Cindy Lien, focuses on Neuroanesthesia. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: Degenerative Spine Disease, Craniosynostosis, Supratentorial tumors (including awake craniotomies), Suboccipital Procedures, Acute Stroke, Acute Spinal cord injury, Decompressive surgery for patients with TBI, Neuromonitoring and more.

The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.

This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in surgical critical care. The book reviews up to date data regarding the management of common problems that arise in the Surgical Intensive Care Unit. The protocols, care bundles, guidelines and checklists that have been shown to improve process measures, and in certain circumstances, are discussed in detail. The text also discusses several well designed randomized prospective trials conducted recently that have altered the way we care for surgical patients with traumatic brain injury, hemorrhagic shock, acute respiratory distress syndrome, and sepsis. This book provides the practicing physician with a clinically oriented practical approach to handle basic and complex issues in the Surgical Intensive Care Unit. This text will serve as a very useful resource for physicians dealing with critically ill surgical patients. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information. This text will become an invaluable resource for all graduating fellows and practicing physicians who are taking the surgical critical care board examinations.

This book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows.

The Objective Structured Clinical Examination (OSCE) is an established section in the part I examination and in many anaesthetic examinations throughout the world. It enables the examiners to assess a candidate's performance in a variety of areas and in topics that were not previously tested. The first edition sought to give examples of OSCE stations with answers. It was hoped that this would be of benefit to candidates as well as trainers looking for guidance about the type and style of stations that might be encountered. The second edition gives more examples of stations with answers. Candidates should find the answers helpful in assessing the level of knowledge required. Many stations require candidates to have a well-rehearsed system for them like examining the anaesthetic machine, or a system of the body. The second edition has been expanded to include these systems. More background information has been included so that once a system is understood it can be applied to different situations.

Vastly expanded and completely re-written, this is the definitive companion and revision aid for the short answer paper which forms part of the Final FRCA examination. It includes a comprehensive introduction to this section of the examination together with details of examination technique (much of which applies both to oral and to written questions). It contains 180 sample questions which cover the breadth of the specialty and which are divided into subspecialty areas. Each question is prefaced with a comment about the topic which attempts to place it in context to suggest the underlying rationale and to indicate its importance.

The modern obstetric anaesthetist must not only provide safe and effective pain-relief in labour and anaesthesia for Caesarean section, but also understand the wider role of the anaesthetist in the management of the pregnant woman. Originally published in 2002, Textbook of Obstetric Anaesthesia is a comprehensive, fully illustrated account of all aspects of modern obstetric anaesthesia. It provides useful, practical, evidence-based information on all aspects of labour ward management. Written by a multidisciplinary team of expert contributors, it features comprehensive chapters covering everything from departmental audit to cutting-edge practice for neonatal resuscitation and administration of mobile epidurals. It will be useful for both the trainee and practising obstetric anaesthetist.

The aim of this text is to provide the framework for building a clinical trial as it pertains to operative and non operative invasive procedures, how to get it funded and how to conduct such a trial up to publication of results The text provides all details of building a scientifically and ethically valid proposal, including how to build the infrastructure for a clinical trial and how to move it forward through various funding agencies. The text also presents various types of clinical trials, the use of implantable devices and FDA requirements, and adjuncts to clinical trials and interaction with industry Clinical Trials Design in Invasive Operative and Non Operative Procedures will be of interest to all specialists of surgery, anesthesiologists, interventional radiologists, gastroenterologists, cardiologists, and pulmonologists

Nurses are playing an increasingly important part in the multidisciplinary team caring for those with chronic pain and this book will raise awareness among nurses of the contribution that they make to those in their care. It provides a resource that explains the mechanisms that cause chronic pain, the impact this pain has on the patient and their family, and the approaches that can be used effectively to help patients come to terms with ongoing pain.

The contributors are all leading nurse specialists in the field, and topics covered include the effects of nutrition on pain, massage, acupuncture, pain in older people and a discussion of the developing role of nurses in this important clinical area.

A knowledge of anatomy has always played a vital role in medicine, and is especially important in the everyday practice of anaesthesia. This 2002 text presents the core anatomical knowledge required for the Primary and Final FRCA examinations in a simple and straightforward manner. Adopting the philosophy of the examination itself, where candidates are often required to reproduce simple line drawings to illustrate the depth of their knowledge, the many illustrations in the book are clear and easy to understand at a glance. The illustrations are accompanied by explanatory text throughout and for each anatomical region, sample examination questions are included which follow the format of those asked in the examinations. This book will interest anaesthesia Primary and Final candidates, as well as providing a valuable quick reference for busy anaesthetists at all levels of experience.

This title contains 2 DVDs. DVD 1 - "Essentials of ABG": Understand in simple language various parameters of the blood gas report including the Sa02, Pa02, PB, Pi02, Fi02, PaCO2, A-a D02, pH and much more. Understand how and why normal and abnormal values are achieved and what their clinical signifi-cance is. This DVD is at least equivalent to 10 hours of reading. DVD 2 - "Details of ABG": It explains step by step as to how to interpret the blood gas report without using a paper, pen or calculator; It discusses simple and then mixed acid base disorders. Common conditions like metabolic acidosis, metabolic alkalosis, Respiratory Acidosis are explained in more details. This DVD is equivalent to at least 20 hours of reading and trains the reader for a life time in less than an hour.

Think the anesthesia oral boards are no laughing matter? Then you haven't read Board Stiff Three. The new edition of this popular anesthesia review book is written in the same winning style that was the hallmark of Board Stiff Too. Dr. Gallagher's signature humor and engaging writing style make this terrific prep book a fun read while still delivering all the most important things you need to know for the boards. In addition to a thorough content review, the new edition also features an extensive section with self-assessment questions. It also includes a bonus DVD with simulated board scenarios that will further help you prepare for the boards. Provides the ideal study guide for the anesthesia oral board exams. Incorporates a unique and humorous approach to make braving the oral exams as enjoyable as possible. Uses the same format as the real exams: clinical scenes are presented, followed by preoperative, intraoperative, and postoperative questions. Includes a bonus DVD with simulated board scenarios.

Make breathwork an indispensable part of your everyday self-care routine with this step-by-step guide to mindful breathing. New science has revealed the importance of breathwork to balance the body, focus the mind, relieve stress, address anger issues and so much more! This little self-care book will take you on a breathtaking journey of holistic healing, featuring: -A down to earth guide to tackle over 50 step-by-step techniques to use at home -Detailed information based on a 360 degree approach to improving breathing techniques written by an expert in the field -Features practices, routines and exercised accompanied by step-by-step illustrations Dive deep into the pages of this brilliant breathwork book to explore expert advice on a diverse range of topics, including body position, depth of breath, speed of breath, visualization, duration and repetition. These easy-to-follow techniques further include conscious and connected breathing, holographic breathwork, and qi gong breathwork, all encompassed within a bite-sized self-help bible full of friendly advice and accompanying illustrations to help make life-transforming change a reality for you! A recent study suggests that pranayama - a form of yoga breathing, can decrease stress-related inflammation, in addition to reducing stress, lowering blood pressure and improving immunity. It's time to tap into the ever-growing trend of wellness, and immerse yourself in the power of breathing, from slowing down and being aware of your breath, to recognizing your own unique rhythms, this all-encompassing self-care book truly does have it all. Did you know that self-care is a vital tool for navigating the challenges of modern living? In a society where stress and anxiety mounts and self-esteem takes a dive, it can be challenging to know where to begin. Don't worry, DK has got you covered! Whether you're experiencing stress and anxiety in your work or personal life and you're seeking a wider range of self-care practices, or you wish to widen your knowledge and experience on breathing techniques through yoga and meditation, this wonderful well-being book has something for everyone to discover. It's time to wake up to the true power of breathwork and enhance the quality of your life for the better. At DK, we believe in the power of discovery. So once you've completed Breathwork why not explore more books in DK's Little Book of Self-Care series? Discover how to make aromatherapy an indispensable part of your everyday self-care routine in Aromatherapy, or immerse yourself in mindfulness massage with Trigger Points.

"Extracorporeal Membrane Oxygenation : An Interdisciplinary Problem-Based Learning Approach" provides an overview of the latest techniques, management strategies and technology surrounding the clinical use of ECMO. This interdisciplinary book reviews the most common scenarios of ECMO in 62 chapters exploring the conditions and problems arising in ECMO practice. Each chapter begins with a stem case, followed by open questions to encourage critical thinking and enable the reader to follow the management strategies of the authors, who are world leaders in the field. Followed by an evidence-based discussion, each chapter concludes with multiple-choice questions for self-assessment. This book is current in its knowledge of organ systems and management and keeps pace with new ECMO technology and surgical techniques coupled with current guidelines for management. Starting with the history of ECMO to technical aspects, circuit biocompatibility and interaction with blood, drugs and flow physics, the volume continues into pediatric and adult sections, focussing on both respiratory and cardiovascular support, followed by a section on trauma. The volume then concludes with a section on neurologic complications and ethics, as well as rehabilitation and ambulation of ECMO patients. In addition, to reflect the current global health situation, this book also includes a chapter on ECMO management in patients suffering with COVID-19, to cover the most urgent and pressing questions around ECMO during the ongoing pandemic. This is the first ECMO book on the market to utilise a problem-based learning approach and as such is an important unprecedented project on ECMO education.