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Books > Medicine > Other branches of medicine > Anaesthetics

Fundamentals of Pain Medicine (Paperback, 1st ed. 2018): Jianguo Cheng, Richard W. Rosenquist Fundamentals of Pain Medicine (Paperback, 1st ed. 2018)
Jianguo Cheng, Richard W. Rosenquist
R2,972 Discovery Miles 29 720 Ships in 10 - 15 working days

Characterized by clarity and straddling the line between scope and depth of information, this concise book provides physicians a comprehensive overview of pain medicine. Chapters are written by some of the leading minds in pain medicine and feature case studies, key points and suggested readings. Multidisciplinary approaches to the clinical and financial challenges of pain with the goal of improving patient quality of life are also discussed. Additionally, the book is in is in tight alignment with the information that trainees are expected to master for the American Board of Anesthesiology's pain medicine subspecialty certification, as outlined by the Joint Council on Anesthesiology Examinations; it covers the diagnosis of pain states, the management of pain, acute pain, radicular pain, neuropathic pain, chronic visceral pain, headaches, and special populations. This book is a must-have for anyone new to pain medicine or studying for the subspecialty certification.

Integrative Pathways - Navigating Chronic Illness with a Mind-Body-Spirit Approach (Paperback, Softcover reprint of the... Integrative Pathways - Navigating Chronic Illness with a Mind-Body-Spirit Approach (Paperback, Softcover reprint of the original 1st ed. 2018)
Angele McGrady, Donald Moss
R1,898 Discovery Miles 18 980 Ships in 10 - 15 working days

This expansive text offers a comprehensive mind/body/spirit framework for relieving individual patients of the debilitating effects of long-term disease while reducing the public burden of chronic illness. It introduces the patient-centered Pathways Model, featuring a robust scientific base for psychotherapy, complementary and alternative modalities, and a religious/spiritual element, in progressive levels of treatment from self-help to professional help. Chapters spotlight component skills of the model, including treatment planning, patient rapport, and choosing therapies for optimal well-being. The authors advocate for interventions ranging from lifestyle change to mindfulness, and biofeedback to pastoral counseling. In addition, in-depth case studies detail memorable patient journeys from diagnosis and referral to assessment, engagement in treatment and outcome. Among the topics covered: * Mind, body, and spirit in chronic illness. * The need for an integrative model to support comprehensive health-supportive change. * Chronic disease from a functional medicine perspective. * Mechanisms by which religious engagement and religion-based variables affect health. * Complementary and integrative medicine for the Pathways Model. * PLUS: Pathways approaches to chronic pain, caregiver stress, diabetes, mood disorders, PTSD, brain injury, heart disease, cancer, and more. Emphasizing patient individuality and clinician creativity, Integrative Pathways models a compassionate approach to lessening persistent suffering for use by health psychologists, physicians, counselors, health coaches, and other practitioners involved in complementary and integrative medicine, pain medicine, and rehabilitation. "The Pathway Model addresses what clinical researchers in the field have been calling for, a research-based approach to health and wellness that clearly explains important concepts and provides an optimal foundation from which to approach health interventions." Patrick R. Steffen, PhD, BCB, Brigham Young University

Hypnotherapy Of Pain In Children With Cancer (Paperback): Josephine R. Hilgard, Samuel Lebaron Hypnotherapy Of Pain In Children With Cancer (Paperback)
Josephine R. Hilgard, Samuel Lebaron
R1,107 Discovery Miles 11 070 Ships in 12 - 19 working days

Presents findings on the effects of hypnosis in reducing anxiety and pain in children with cancer and suggests that hypnotherapy offers real promise of pain relief without drugs.First published in 1991. Routledge is an imprint of Taylor & Francis, an informa company.

OSCEs for the Final FFICM (Paperback): Raj Nichani, Brendan McGrath OSCEs for the Final FFICM (Paperback)
Raj Nichani, Brendan McGrath
R1,521 Discovery Miles 15 210 Ships in 9 - 17 working days

This study guide includes in-depth coverage of past FFICM exam material, and is an invaluable resource for trainees preparing for the OSCE examination in intensive care medicine. A structured layout gives the reader clear and convenient access to a wealth of model questions and answers that can be used for quick-fire practice or more detailed study. The book is divided into four sections covering data interpretation, equipment, ethics and communication, and resuscitation and simulation. Questions have been matched to the curriculum, ensuring accurate and comprehensive revision guidance, and a sample marking scheme is provided to assist with exam preparation. Incorporating recommendations from the FFICM Court of Examiners, additional data analysis, images and ECGs are included to build on common areas of potential improvement.

Anasthesie Beim Geriatrischen Patienten (German, Hardcover): Wolfgang Zink, Bernhard Graf, York Zausig, Hans Jurgen Heppner Anasthesie Beim Geriatrischen Patienten (German, Hardcover)
Wolfgang Zink, Bernhard Graf, York Zausig, Hans Jurgen Heppner
R2,871 R2,285 Discovery Miles 22 850 Save R586 (20%) Ships in 10 - 15 working days
Reviews of Physiology, Biochemistry and Pharmacology Vol. 170 (Paperback, Softcover reprint of the original 1st ed. 2016):... Reviews of Physiology, Biochemistry and Pharmacology Vol. 170 (Paperback, Softcover reprint of the original 1st ed. 2016)
Bernd Nilius, Pieter De Tombe, Thomas Gudermann, Reinhard Jahn, Roland Lill, …
R3,212 Discovery Miles 32 120 Ships in 10 - 15 working days

Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

Muskelrelaxanzien - Ein Kompendium (German, Hardcover): Rafael Dudziak Muskelrelaxanzien - Ein Kompendium (German, Hardcover)
Rafael Dudziak
R1,579 Discovery Miles 15 790 Ships in 12 - 19 working days

Seit der ErwAhnung von Curare kurz nach der ersten Reise von Kolumbus nach Amerika sind 450 Jahre, seit der ersten Anwendung des Muskelrelaxans Curare in der AnAsthesie erst knapp 60 Jahre vergangen. Inzwischen ist der Gebrauch neuromuskulArer Blocker Routine geworden, ohne dass sich an der potentiellen GefAhrlichkeit ihrer Wirkung etwas geAndert hat.
Das vorliegende Kompendium liefert den "State of the art" zum Thema Muskelrelaxanzien: Die Geschichte, die Physiologie und Pathophysiologie der neuromuskulAren Aoebertragung, die klinische Anwendung und Aoeberwachung der neuromuskulAren Blockade werden nach dem aktuellen Wissensstand dargestellt. Ein Buch fA1/4r AnAsthesisten und AnAsthesie-Krankenpflegepersonal.

Total Intravenous Anaesthesia  (Principles and Practice in Anaesthesia Series, Edited by CEW Hahn and AP Adams) (Paperback): I.... Total Intravenous Anaesthesia (Principles and Practice in Anaesthesia Series, Edited by CEW Hahn and AP Adams) (Paperback)
I. Smith
R1,716 Discovery Miles 17 160 Ships in 12 - 19 working days

Total intravenous anaesthesia (TIVA) has long been used for specialized surgery, but recent developments in monitoring and delivery and the availability of the intravenous anaesthetic protocol have opened the door to widespread application.

This new addition to the Principles and Practice series is a straightforward introduction to TIVAA, starting with the basic pharmokinetic and dynamic principles and moving on to an overview of the pharmacology of the major intravenous anaesthetic drug groups. The importance of drug interactions are stressed and there is a discussion of the latest technology in delivery and monitoring-such as target controlled infusions and EEG bispectral monitoring systems.

Written by key specialists from the UK and the USA, this practical reference will be an essential introduction for all anaesthetic and intensive care trainees, and will enable anaesthetists to keep up to date on the rapid expansion of TIVA in clinical practice.

Assistierter Suizid: Der Stand der Wissenschaft 2016 (English, German, Paperback, 1. Aufl. 2017 ed.): Gian Domenico Borasio,... Assistierter Suizid: Der Stand der Wissenschaft 2016 (English, German, Paperback, 1. Aufl. 2017 ed.)
Gian Domenico Borasio, Ralf J. Jox, Jochen Taupitz, Urban Wiesing
R2,340 Discovery Miles 23 400 Ships in 10 - 15 working days

Das Buch dokumentiert die Beitrage des internationalen Symposiums "Assistierter Suizid: Der Stand der Wissenschaft" vom 15. Juni 2015 in Berlin. Es bietet einen einmaligen Uberblick uber die aktuellen empirischen Untersuchungen zum Thema, die in der politischen Debatte teilweise schlicht ignoriert wurden und immer noch ignoriert werden. Es enthalt ausserdem die Transkripte aufschlussreicher Pro-Contra Debatten zwischen Vertretern unterschiedlicher Positionen aus den Fachgebieten Recht, Medizin und Ethik. Am Schluss steht eine ausfuhrliche Kommentierung des neuen Gesetzes "zur Strafbarkeit der geschaftsmassigen Forderung der Selbsttotung" aus rechtlicher, medizinischer und ethischer Perspektive.Die Autoren und Herausgeber sind international ausgewiesene Experten aus Deutschland und aus anderen Staaten, in denen die Totung auf Verlangen und/oder der assistierte Suizid gesetzlich geregelt sind (Niederlande, Schweiz, USA).

Muscles, Nerves, and Pain - A Guide to Diagnosis, Pain Concepts and Therapy (Paperback, 2nd ed. 2017): Wilfred A. Nix Muscles, Nerves, and Pain - A Guide to Diagnosis, Pain Concepts and Therapy (Paperback, 2nd ed. 2017)
Wilfred A. Nix
R3,486 Discovery Miles 34 860 Ships in 10 - 15 working days

Many patients suffer from problems in their muscles or nerves in combination with pain. This book is about the complex interplay between the causes of these problems and the puzzle they pose. Pain is the subjective experience of a psychophysical phenomenon arising from a defined area in the body. It is a cry for help and challenges the physician to ask the right questions and to carry out the right examinations. If they succeed in doing so, the patient's signs and symptoms will be translated into the present knowledge of pain concepts to initiate appropriate therapy. With this goal in mind, this book summarizes the latest scientific information on pain states and their mechanisms. It provides a deeper understanding of the different pain conditions and allows physicians to form strategies for better pain therapy. The second edition includes more graphs, tables, and illustrations. It is updated with the current and dynamically expanding knowledge on the therapy of several disease states and explains in more detail the processing of pain in the central nervous system. When puzzling symptoms of sensory, motor, and autonomic deficits are evident, an examination has to be performed systematically in order to reach the correct diagnosis. This calls for suitable anatomical knowledge. Depending on where a lesion exists within a peripheral nerve, the root or the plexus, typical patterns of paralysis can be detected. Numerous illustrations in the book help physicians to more easily understand and solve problems of peripheral nerve and root injuries and their sequelae in their daily work.

Understanding Anesthesia - What You Need to Know about Sedation and Pain Control (Hardcover, New): Steven L. Orebaugh Understanding Anesthesia - What You Need to Know about Sedation and Pain Control (Hardcover, New)
Steven L. Orebaugh
R1,177 Discovery Miles 11 770 Ships in 12 - 19 working days

Most people choose their surgeon with care, but very few think about the anesthesiologist, even though that physician's skills and approach can significantly influence surgical outcomes. Here Dr. Steven L. Orebaugh recommends steps we all can take to secure safe and effective anesthesia. What type of anesthesia is used-and how it is applied-directly affects postoperative comfort as well as mental clarity and rehabilitation. This book describes the various options for anesthesia and how they can be used together for the best possible outcome and optimal pain management. Dr. Orebaugh offers a brief history of the subject and a clear and careful overview of the types of anesthesia and their associated complications and risks. Dr. Orebaugh focuses especially on the benefits of regional anesthesia. When appropriately applied-whether alone or with other methods-spinal and peripheral nerve blocks often lead to better recovery and reduced pain. Studies show that as many as half of all surgical patients experience poorly controlled postoperative pain. Regional anesthetic nerve blocks can help significantly in managing this pain while reducing the side effects of general anesthetics and pain medications. A better understanding of anesthesia will reassure people contemplating surgery and equip them to take the necessary steps toward healthy recovery. Knowing their options, they can have informed conversations with their doctor and indicate a preference for a specific anesthetic treatment. Written by a compassionate and experienced anesthesiologist and backed by scientifically accurate information and the latest research, this book will help patients do just that.

Pain - A Sociological Introduction (Hardcover): E. Denny Pain - A Sociological Introduction (Hardcover)
E. Denny
R1,558 Discovery Miles 15 580 Ships in 12 - 19 working days

Pain in one form or another is probably the most common symptom presented to medical and healthcare professionals. Long a subject of biomedical interest, more recent biopsychosocial theories have extended the study of pain as a concept which is highly individual in the way it is experienced. Today s landscape offers a broad array of approaches to understanding pain and, crucially, to alleviating its impact. This concise and accessible volume aims to make sense of what is at first sight an eclectic mix of theoretical and practical work on pain, from a distinctly sociological perspective. While there has been much quantitative medical research on pain, in exploring sociology s important contributions to this field Elaine Denny offers insight into the world of those living with pain and the meaning it has in their lives. She provides readers with a range of explanations of pain and various influences on the experience of pain, critically analysing competing schools of thought and embedding this work in the everyday practice of providing care. The result is an illuminating volume for students of health and medical professions studying pain, the body, and the sociology of health and illness.

Perioperative Care of the Elderly - Clinical and Organizational Aspects (Hardcover): Gabriella Bettelli Perioperative Care of the Elderly - Clinical and Organizational Aspects (Hardcover)
Gabriella Bettelli
R2,781 Discovery Miles 27 810 Ships in 12 - 19 working days

This innovative, comprehensive book covers the key elements of perioperative management of older patients. The book's chapter structure coincides with the clinical path patients tread during their treatment, from preoperative evaluation to post-hospital care. Epidemiological aspects and aging processes are illustrated, providing keys to understanding the quick expansion of geriatric surgery and defining the clinical profile of older surgical patients in a cybernetic perspective. Preoperative evaluation and preparation for surgery, including medication reconciliation and pre-habilitation, are developed in the light of supporting decision-making about surgery in an evidence-based and patient-focused way. Intra- and postoperative management are discussed, aiming to tailor anesthetic, surgical and nursing approaches to specific patients' needs, in order to prevent both general and age-related complications. This volume also addresses issues relevant to geriatric surgery, from different organizational models to clinical risk management and systems engineering applied to hospital organization.

Pain, Emotion and Cognition - A Complex Nexus (Paperback, Softcover reprint of the original 1st ed. 2015): Gisèle Pickering,... Pain, Emotion and Cognition - A Complex Nexus (Paperback, Softcover reprint of the original 1st ed. 2015)
Gisèle Pickering, Stephen Gibson
R3,543 Discovery Miles 35 430 Ships in 10 - 15 working days

This book focuses on the reciprocal interactions between pain, emotion and cognition. International experts report on their findings, clinical experience and the most recent literature on the complex relations between these three domains. Clinical, psychological, behavioral and neuroimaging approaches converge towards aiding patients suffering from pain, cognitive impairment or emotional distress. Beyond the pathophysiological aspects of pain, difficulties encountered with patients are analyzed and strategies are proposed to optimize treatment, doctor-patient relationships, and patient well-being. This work will appeal to a broad readership, from clinical medical practitioners to psychologists, nurses and pain specialists.

Electrical Stimulation for Pelvic Floor Disorders (Paperback, Softcover reprint of the original 1st ed. 2015): Jacopo... Electrical Stimulation for Pelvic Floor Disorders (Paperback, Softcover reprint of the original 1st ed. 2015)
Jacopo Martellucci; Foreword by Ernest H.J. Weil, K. Matzel
R2,876 Discovery Miles 28 760 Ships in 10 - 15 working days

This book will enable the reader to gain a sound understanding of contemporary and futuristic evidence-based interventions and assessment procedures for pelvic floor disorders. It gathers the experiences of some of the most important experts on electrical stimulation techniques, offering a multidisciplinary and problem-oriented approach organized according to therapeutic goals. Interventions are recommended that are consistent with theory and display clinical efficacy for specific disorders, including urinary incontinence or retention, fecal incontinence, constipation, pelvic pain, sexual dysfunction and neurological diseases involving the pelvic floor. All of the surgical or rehabilitative techniques requiring electrical stimulation for the treatment of these disorders are explored and essential background information is provided on functional anatomy, neurophysiology and concepts in electrotherapy. This volume will be a very useful tool for urologists, general or colorectal surgeons, gynecologists and anesthesiologists and also physiotherapists and alternative medicine practitioners (a specific chapter focuses on electroacupuncture). It will assist in their clinical practice as they seek to help the very many patients who suffer from any of the wide range of functional pelvic floor disorders.

Placebo (Paperback, Softcover reprint of the original 1st ed. 2014): Fabrizio Benedetti, Paul Enck, Elisa Frisaldi, Manfred... Placebo (Paperback, Softcover reprint of the original 1st ed. 2014)
Fabrizio Benedetti, Paul Enck, Elisa Frisaldi, Manfred Schedlowski
R6,444 Discovery Miles 64 440 Ships in 10 - 15 working days

Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.

Perioperative Kidney Injury - Principles of Risk Assessment, Diagnosis and Treatment (Paperback, Softcover reprint of the... Perioperative Kidney Injury - Principles of Risk Assessment, Diagnosis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2015)
Charuhas V. Thakar, Chirag R. Parikh
R3,578 Discovery Miles 35 780 Ships in 10 - 15 working days

The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends the evidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.

Psychopharmacology in Oncology and Palliative Care - A Practical Manual (Paperback, Softcover reprint of the original 1st ed.... Psychopharmacology in Oncology and Palliative Care - A Practical Manual (Paperback, Softcover reprint of the original 1st ed. 2014)
Luigi Grassi, Michelle Riba
R3,827 Discovery Miles 38 270 Ships in 10 - 15 working days

This practical manual presents the main drugs and protocols currently used in the psychopharmacological treatment of psychiatric disorders in cancer and palliative care settings and explores the principal issues involved in such treatment. Significant clinical challenges encountered in the psychopharmacological management of various psychiatric conditions are discussed, covering aspects such as side-effects and drug-drug interactions. Attention is also paid to the emerging theme of adjuvant use of psychotropic drugs for the treatment of symptoms or syndromes not primarily related to psychiatric disorders. In addition, practical suggestions are provided for dealing with special populations, including children and the elderly. The book is designed to be easy to read and to reference, with helpful concise tables and boxes. The authors include some of the most renowned clinicians working in the field of psycho-oncology.

Uncommon Diseases in the ICU (Paperback, Softcover reprint of the original 1st ed. 2014): Marc Leone, Claude Martin, Jean-Louis... Uncommon Diseases in the ICU (Paperback, Softcover reprint of the original 1st ed. 2014)
Marc Leone, Claude Martin, Jean-Louis Vincent
R4,705 Discovery Miles 47 050 Ships in 10 - 15 working days

This book highlights the practical characteristics of uncommon diseases and presents the most relevant features for the management of intensive care units. It does not aim to provide an exhaustive description of uncommon diseases, focusing instead on the major diseases that intensivists may encounter in their clinical practice. After a brief introduction on the epidemiology and pathophysiology of each disease, the authors emphasize the aspects related to diagnosis and treatment, providing concise and pragmatic guidance for residents and intensivists who care for patients with uncommon diseases. Although by definition uncommon diseases have a low prevalence in the general population, they can affect a large number of patients admitted to intensive care units, as they can often be diagnosed at intensive care units. Indeed, often a complication of the disease is what leads to the patient's being admitted to an intensive care unit.

Geriatric Trauma and Critical Care (Paperback, Softcover reprint of the original 1st ed. 2014): Jay A. Yelon, Fred A. Luchette Geriatric Trauma and Critical Care (Paperback, Softcover reprint of the original 1st ed. 2014)
Jay A. Yelon, Fred A. Luchette
R5,956 Discovery Miles 59 560 Ships in 10 - 15 working days

Geriatric Trauma and Critical Care provides a multidisciplinary overview of the assessment and management of the elderly patient presenting with surgical pathology. By utilizing current literature and evidence-based resources, the textbook elucidates the unique nature of caring for the elderly population. The structure of the volume provides the reader with an overview of the physiologic and psychological changes, as well as the impact on the healthcare system, associated with the aging process. Emphasis is placed on the impact of aging, pre-existing medical problems, effects of polypharmacy, advanced directives and end-of-life wishes on acute surgical problems, including trauma and surgical critical care. Special attention is given to the ethical implications of management of the aged. The multidisciplinary contributors provide a unique point of view not common to surgical texts. The textbook is the definitive resource for practicing surgeons, emergency medicine physicians, intensivists, anesthesiologists, hospitalists, geriatricians, as well as surgical residents, nurses and therapists, all who care for elderly patients with surgical emergencies.

Chronic Postsurgical Pain (Paperback, Softcover reprint of the original 1st ed. 2014): Gerard Mick, Virginie Guastella Chronic Postsurgical Pain (Paperback, Softcover reprint of the original 1st ed. 2014)
Gerard Mick, Virginie Guastella
R2,021 Discovery Miles 20 210 Ships in 10 - 15 working days

Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

Analgesia - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010): Arpad Szallasi Analgesia - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010)
Arpad Szallasi
R3,320 Discovery Miles 33 200 Ships in 10 - 15 working days

Chronic pain is a complex phenomenon, which continues to remain undertreated in the majority of affected patients thus representing a significant unmet medical need, but the development of cellular, subcellular, and molecular methods of approaching this epidemic of pain shows great promise. In Analgesia: Methods and Protocols, experts in the field present thorough coverage of molecular analgesia research methods from target discovery through target validation and clinical testing to tolerance and dependence, with extensive chapters on emerging receptor classes as targets for analgesic drugs and innovative analgesic strategies. As a volume in the highly successful Methods in Molecular Biology (TM) series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes sections with tips on troubleshooting and avoiding known pitfalls. Comprehensive and essential, Analgesia: Methods and Protocols promises to aid and enrich the research of all those scientists and clinicians who are interested in what the increasingly molecular future has in store for analgesia research, from the molecular research bench through the animal laboratory to the bedside.

Neurobiological Studies of Addiction in Chronic Pain States (Paperback, Softcover reprint of the original 1st ed. 2014):... Neurobiological Studies of Addiction in Chronic Pain States (Paperback, Softcover reprint of the original 1st ed. 2014)
Carolyn A. Fairbanks, Thomas J. Martin, Ph.D.
R3,235 Discovery Miles 32 350 Ships in 10 - 15 working days

Using rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction.

Pain Research - Methods and Protocols (Paperback, Softcover reprint of the original 2nd ed. 2012): Z. David Luo Pain Research - Methods and Protocols (Paperback, Softcover reprint of the original 2nd ed. 2012)
Z. David Luo
R4,167 Discovery Miles 41 670 Ships in 10 - 15 working days

The advancements of medical technology, improvements in medical care, and increased patients' life span make pain research and related drug development high priorities for both the research community and pharmaceutical companies. Rapid development of basic science research tools, such as techniques of flurometric labeling, genomic and proteomic high throughput screening, and genetically modified animals, promotes the swift acceleration of pain research to a stage allowing integrated investigations of pain processing mechanisms at the single cell and/or molecule level, and in a spatially and temporally controlled manner. Using multidisciplinary approaches, we can dissect the complicity of the sensory circuits connecting peripheral stimulation to maladaptive changes in the sensory pathways as well as pain perceptions at the central nervous system. Pain Research: Methods and Protocols, Second Edition provides advanced techniques and animal models that are critical for integrated pain research. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Pain Research: Methods and Protocols, Second Edition serves as an ideal guide to novice pain researchers who may not have extensive experiences in the field, or to experienced pain researchers who would like to expand their research in new directions and/or to new mechanisms in different models.

Sepsis Management - PIRO and MODS (Paperback, Softcover reprint of the original 1st ed. 2012): Jordi Rello, Jeffrey Lipman,... Sepsis Management - PIRO and MODS (Paperback, Softcover reprint of the original 1st ed. 2012)
Jordi Rello, Jeffrey Lipman, Thiago Lisboa
R3,134 Discovery Miles 31 340 Ships in 10 - 15 working days

This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

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