Everyone experiences pain, whether it's emotional or physical, chronic or acute. Pain is part of what it means to be human, and so an understanding of how we relate to it as individuals - as well as cultures and societies - is fundamental to who we are. In this important new book, the first in Routledge's new Critical Approaches to Health series, Robert Kugelmann provides an accessible and insightful overview of how the concept of pain has been understood historically, psychologically, and anthropologically. Charting changes in how, after the development of modern painkillers, pain became a problem that could be solved, the book articulates how the possibilities for living with pain have changed over the last two hundred years. Incorporating research conducted by the author himself, the book provides both a holistic conception of pain and an understanding of what it means to people experiencing it today. Including critical reflections in each chapter, Constructing Pain offers a comprehensive and enlightening treatment of an important issue to us all and will be fascinating reading for students and researchers within health psychology, healthcare, and nursing.

Plum and Posner's Diagnosis and Treatment of Stupor and Coma, 5th edition, is a major update of the classic work on diagnosing the cause of coma, with the addition of completely new sections on treatment of comatose patients, by Dr. Jan Claassen, the Director of the Neuro-ICU at Columbia New York Presbyterian Hospital. The first chapter of the book provides an up-to-date review on the brain mechanisms that maintain a conscious state in humans, and how lesions that damage these mechanisms cause loss of consciousness or coma. The second chapter reviews the neurological examination of the comatose patient, which provides the basis for determining whether the patient is suffering from a structural brain injury causing the coma, or from a metabolic disorder of consciousness. The third and fourth chapters review the pathophysiology of structural lesions causing coma, and the specific disease states that result in coma. Chapter five is a comprehensive treatment of the many causes of metabolic coma. Chapter 6 review psychiatric causes of unresponsiveness and how to identify and treat them. Chapters 7 and 8 review the overall emergency treatment of comatose patients, followed by the treatment of specific causes of coma. Chapter 9 examines the long term outcomes of coma, including the minimally conscious state and the persistent vegetative state, and how they can be distinguished, and their implications for eventual useful recovery. Chapter 10 reviews the topic of brain death and the standards for examination of a patient that are required to make the determination of brain death. The final chapter 11 is by J.J. Fins, a medical ethicist who was invited by the other authors to write an essay on the ethics of diagnosis and treatment of patients who, by definition, have no way to approve of or communicate about their wishes. While providing detailed background for neurological and neurosurgical specialists, the practical nature of the material in this book has found its greatest use among Internists, Emergency Medicine, and Intensive Care specialists, who deal with comatose patients frequently, but who may not have had extensive neurological training.

During the First European Congress of Anesthesiology, held in Vienna, Austria, in September, 1962, panel discussions on nineteen different subjects were held, each lasting approxi mately three hours. One, concerning Controversial Aspects of Resuscitation, was later edited by its chairman, PETER SAFAR, and published in 1963. At the request of the publisher, the discussion on hypnosis has been edited in a similar manner. The participants in the discussion on Hypnosis in Anes thesiology had agreed, prior to the meeting, on a list of questions to be debated, and Dr. STOKVIS' introductory statement on the nature of hypnosis was circulated among them in appropriate translations in order to give the debate a starting point. It had also been agreed that no formal papers should be read after this introduction, and that the participants should use at will the German, English or French language. Following each contribution it was the chairman's task to give a brief summary in the two other languages. Discussion was therefore somewhat slowed down and occasionally rendered difficult by misunderstandings or the omission of details. Drs. GUEGUEN, MOSCONI, and VOLGYESI, who were not able. to attend, had sent written contributions which the chairman presented briefly during the discussion. The present text has been worked out of the tape recording of the discussion and the chairman's correspondence with the panelists some time after the meeting. Whenever the original contributions were in French or German, the English translation has been the chairman's."

Epidural Anaesthesia: Images, Problems and Solutions brings together the most comprehensive collection of post-block epidurograms in the world into a single volume. With accompanying X-rays and contrast injection images, it clearly explains why an epidural block has failed and provides practical advice on how to avoid complications in the future. Key featuers: Contains over 180 clearly labelled X-rays and contrast injection images to help you learn using these examples. Uses X-rays and contrast injection images rather than more complext imaging technologies, to allow quick assessment of blocks in the most basic radiology department. Written by a world-renowned expert, providing consistency of style and approach throughout. Companion website contains downloadable images as well as moving X-rays of contrast injection, 3D reconstructions and explanatory cartoons. This unique book for specialist and trainee anaesthetists demonstrates, with simple X-rays and contrast injection, why epidurals are occasionally imperfect. Epidural Anaesthesia: Images, Problems and Solutions will enable you to refine your technique and avoid adverse outcomes in practice.

The First European Congress of Anesthesiology in Vienna, Austria in September, 1962 presented 19 Symposium discussions, each lasting approximately 3 hours. Unlike most of these panels, the one on Resuscitation was a free discussion on controversial topics, without presentation of formal papers. In spite of the spontaneity of the unrehearsed questions and ans wers, the participants feit that an edited version of this Symposium should be published. The reasons for publication included the inter national character of the group of participants and the recent general interest in respiratory and circulatory resuscitation. A presentation of accepted resuscitation techniques was omitted, because of lack of time and because the Symposium was held pri marily for trained anesthesiologists, most of whom have first-hand experience with resuscitation and should be familiar with the accepted modern methods. Only controversial topics, which seemed to be of interest to those with personal experience in the application and the research of resuscitation, were included."

Pharmacology and physiology are the foundation of every anesthesia provider's training and clinical competency. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2nd Edition, delivers the information you need in pharmacology, physiology, and molecular-cellular biology, keeping you current with contemporary training and practice. This thoroughly updated edition is your one-stop, comprehensive overview of physiology, and rational anesthetic drug selection and administration, perfect for study, review, and successful practice. Contains new chapters on Special Populations (anesthetic pharmacology in obesity, geriatrics, and pediatrics), Oral and Non-IV Opioids, Thermoregulation, Physiology and Pharmacology of Obstetric Anesthesia, Chemotherapeutic and Immunosuppresive Drugs, and Surgical Infection and Antimicrobial Drugs. Incorporates entirely new sections on Physics, Anatomy, and Imaging. Includes new information on consciousness and cognition, pharmacodynamics, the immune system, and anti-inflammatory drugs. Features user-friendly tables, figures, and algorithms (including 100 new illustrations), all presented in full color and designed to help explain complex concepts. Helps you understand the molecular mechanism of drug actions and identify key drug interactions that may complicate anesthesia with dedicated sections on these areas. Expert ConsultT eBook version included with purchase, which allows you to search all of the text, figures, and references from the book on a variety of devices

This book is a practical revision aid for postgraduates preparing for Final FRCA (Fellowship of the Royal College of Anaesthetists) written examinations. Presented in the style of the newly introduced CRQ (Constructed Response Questions) format, the book features five complete papers, each containing twelve questions. Topics cover the entire examination syllabus. Detailed answers are given for every question, as well as comprehensive references for further reading. Key points Practical revision aid for candidates preparing for Final FRCA examinations Presented in the style of the new CRQ format Includes five papers each containing twelve questions with detailed answers Topics cover the complete exam syllabus

Low Back Disorders, Third Edition With Web Resource, guides readers through the assessment and treatment of low back pain, providing evidence-based research on the best methods of rehabilitation and prevention of future injury. In this book, internationally recognized low back specialist Stuart McGill presents the research and applications of back anatomy and biomechanics to build effective prevention and rehabilitation programs for patients or clients. This third edition of Low Back Disorders contains all of the essential tools for those with low back maladies. Strong foundational information on anatomy and injury mechanisms guide readers through the essential functions of the structures of the low back and related tissues, and common misconceptions about pain and discomfort are addressed and corrected. The text provides detailed insights into injury assessment by an extensively expanded set of tests with accompanying instructions. These provide guidance and recommendations for individualized rehabilitation strategies and exercises. Also new to this edition is a web resource featuring 20 fillable Handouts for Patients or Clients that can be edited and printed to suit practitioner and patients’ needs. The web resource also contains an online video suite that showcases various exercises and assessments. In addition to offering strategies for relieving and potentially eliminating pain, the text provides insight into the conditions and environments that may initially cause back pain and makes recommendations on reducing these influences so that clients can be pain free. This book contains more than 500 photos, graphs, and charts on anatomy, biomechanics, and assessments; 50 tests and exercises with step-by-step instructions are available to aid readers in developing successful programs for patients and clients. In addition to the evidence-based foundation of this edition, the following enhancements have been made: • Completely updated information and streamlined chapter organization ensure that practitioners use best clinical practices. • Practical checklists throughout the text provide easy access to testing and assessment clinical techniques and information. • Practical Applications provide clinical information to aid readers in understanding concepts and theory. • To aid instructors, the text includes a newly added image bank to visually support class lectures. Low Back Disorders, Third Edition With Web Resource, contains essential research and corresponding clinical applications in a clear and organized format. Part I introduces the functional anatomy and biomechanics of the lumbar spine. It also presents epidemiological studies on low back disorders and dispels common myths of lumbar spine stability. Part II reviews risk factors for low back disorders and common prevention methods, with specific attention paid to reducing workplace risk factors. Part III explains evaluating and diagnosing clients and developing exercise and rehabilitation programs. Specific exercises that are proven to enhance performance and reduce pain are also explained. Evidence-based research and cutting-edge application strategies from a leading spine specialist in North America make Low Back Disorders, Third Edition With Web Resource, the authoritative text for the examination and rehabilitation of the low back. Its approach to back care will lead readers in developing intervention, rehabilitation, and prevention programs to address the unique needs of each patient or client. Earn continuing education credits/units! A continuing education course and exam that uses this book is also available. It may be purchased separately or as part of a package that includes all the course materials and exam.

Career or Fibromyalgia, Do I Have to Choose? sorts out all the symptoms that are keeping sufferers of fibromyalgia in a cycle of confusion and unable to work. Karen R. Brinklow is the first Certified Fibromyalgia Advisor in Canada, returned to the dream career she thought was over because of fibromyalgia. Throughout Career or Fibromyalgia, Do I Have to Choose?, she shows sufferers how they can too. Karen partners with those suffering from fibromyalgia to take action now and: Reduce pain and fatigue so they feel less confused and frustrated Stop searching for answers so they can gain focus and feel organized Figure out which symptoms to tackle first so they can enjoy life Manage their symptoms and make a plan to return to the job they love Those suffering from fibromyalgia do not have to live like this anymore and do not have to give up the career they love. It's time to get back to work and off the hamster wheel of pain, exhaustion, fuzzy thinking, and stiffness.

This practical book provides a handy reference for the doctor confronted with patients complaining of headache. Headache is one of the most common complaints seen in the outpatient or ambulatory care setting, and may be caused by a wide variety of conditions. This book clearly explains up-to-date headache epidemiology, impact, and pathogenesis, and walks the reader through the steps to evaluating and treating the patient presenting with primary or secondary headache disorders. Also included are reviews of common headache comorbidities, including cardiovascular disease and stroke, epilepsy, fibromyalgia and mood disturbance. Copious use of easy-to-understand figures, tables, and algorithms make this book a useful and practical tool in the clinic. Guidance on selecting diagnostic tests and specific treatment protocols are provided. Treatment recommendations are evidence-based with full referencing and include emerging therapies. Sections on evaluating and treating headaches in children, women during pregnancy, and the elderly complete this comprehensive reference. The likely readership will include the following: neurologists, general physicians, doctors in training, hospital pharmacists, primary care physicians, nurses and nurse practitioners.

The Objective Structured Clinical Examination (OSCE) is a highly reliable and valid tool for the evaluation of trainees in anaesthesia. It enables examiners and trainers to assess a number of competencies in an organised way. Performance in the OSCE is considered to be a fair reflection of the level of knowledge and skill attained during anaesthesia training. Apart from having a wide and deep knowledge on the subject, trainees are expected to have the capacity to demonstrate their competency in a short period of time allotted for each station. The authors of this book have a rich experience in successfully conducting OSCE courses in the United Kingdom. The sample OSCE sets in the book closely simulate the style and content of the Royal College of Anaesthetists' examination format. The book contains 100 OSCE stations with answers based on key practical procedures, clinical skills, communication skills, data interpretation, anaesthetic equipment and the management of critical incidents on a simulator. The answers are presented thoroughly and clearly. The tutorial on the relevant topic and additional key points at the end of each station, together with more than 100 illustrations throughout the book will complement the reader's overall understanding. The marking system signifies the relevance of each question, enabling objective assessment of knowledge and practical skills. This book will also help candidates all over the world to pass highly competitive postgraduate examinations in anaesthesia. It is an invaluable educational resource for all anaesthetists.

This book aims to provide an overview of the basics of anesthesia for neurotrauma. It showcases how management of different neurotrauma cases may differ, especially those involving spine and or polytrauma. It provides quick and easy access to understand anesthesia for neurotrauma.

Given the heightened focus on the opioid crisis and its intersection with adequate chronic pain management, there is an impetus to shift patient care toward self-management and comprehensive interdisciplinary modalities. However, despite the evidence base for efficacy, pain psychology remains largely relegated to the complementary and alternative medicine designations and medical providers struggle to search for trained pain psychologists in their community. This unique book makes core psychological techniques accessible to medical providers and allied health professionals who are on the front lines of routine communication with patients living with chronic pain. Practical suggestions and vignettes demonstrate how to briefly and effectively incorporate key concepts from Cognitive-Behavioral Therapy, Acceptance and Commitment Therapy, Motivational Interviewing and other orientations into any health care setting.

This pack brings together two essential texts on the clinical specialties, covering all core topics for a value-for-money price. Updated with the latest advice and clinical guidelines, packed full of high-quality illustrations, boxes, tables, and classifications, and with a brand new chapter on how to survive your junior doctor years and beyond, the Oxford Handbook of Clinical Specialties is ideal for both study and use at direct point of care. Each chapter is clear and concise and filled with medical gems, with features including ribbons to mark your most-used pages and mnemonics to help you memorize and retain key facts. With reassuring and friendly advice throughout, this is the ultimate guide and revision tool for every medical student and junior doctor for each clinical specialty placement. Accompanying this resource is the fourth edition of Oxford Assess and Progress: Clinical Specialties which features over 400 Single Best Answer questions that are mapped to the medical school curricula. Packed with questions written by experienced doctors in each specialty, and rooted in real-life clinical encounters, this revision tool is an authoritative guide for students. Further reading resources and cross-references to the Oxford Handbook of Clinical Specialties have been fully updated to expand your revision further on topics you find challenging.

Welche Studienergebnisse entsprechen der besten wissenschaftlichen Evidenz? Erfahrene Herausgeber und Autoren stellen hier aktuelle Studienergebnisse nach EBM-Kriterien zusammen. Bereits nach kurzer Zeit in 2., komplett aktualisierter Auflage mit systematischer Gliederung der Inhalte nach den Bereichen Anasthesie und Intensivmedizin. Um viele praxisrelevante Themen erweitert u.a.: der kardiale Risikopatient, Transfusions-und Gerinnungsmanagement, Analgosedierung und Blutzuckermanagement auf der Intensivstation, intensivmedizinische Therapie der Pneumonie, COPD und des akuten Nierenversagens. Ein Werk, das arztliche Entscheidungen auf eine wissenschaftliche Basis stellt und aktuelle Studienergebnisse in den Klinikalltag integriert.

Operating with bare hands, dressed in his street clothes, he had taken those first steps that every training surgeon must take-gripping the handle of a scalpel and making the first, irrevocable cut into live human flesh. For the surgeon training in the early 1840s, these first surgical milestones were performed on a person who would recoil in terror and horror, flinch, pull away, shake-and scream and scream and scream. Until 1846, surgery was performed without anaesthesia: extraordinary operations, carried out on conscious, terrified patients. Surgeons of that era were bold and courageous and saved many lives, but anaesthesia changed everything. With an unconscious patient, the surgeon could take his time. Surgery became slower, more careful and more delicate. And as anaesthesia removed the pain of surgery, the medical world gave more attention to surgical infection, heralding in the use of antiseptics and eventually aseptic surgery. By 1881, the operating theatre was unrecognisable. Much has been written about surgery in the nineteenth century, but little has been said about the development of the relationship between surgeon and anaesthetist. For anaesthesia to mature and allow further advances in surgery, a professional relationship had to develop between surgeons and anaesthetists. Joseph Clover arguably did more than any other anaesthetist to develop that relationship. In The Chloroformist, Christine Ball tells the captivating story of an innovative, hard-working and deeply humane pioneer of modern patient care.

The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians and residents, this medical reference book will effectively prepare you to handle any critical incident during anesthesia. "A comprehensive discussion of the latest theories, principles and practices for CRM in perioperative practice and will be a useful resource for anaesthetists of all grades and levels of experience" Reviewed by British Journal of Anaesthesia, Jun 2015 "...this book contains essential information that all anesthesiologists should know or readily be able to easily reference..." Reviewed by Jane Torrie, Oct 2015 "Every anesthesia provider needs to study, not just read, this new edition, even if you read the first edition. Also, distilled instructions of key elements of the cases covered in this book need to be included in manuals made available for emergencies (although that, too, needs further study on how best to use them). If I were your patient, I would ask if you had studied these principles. If you hadn't, I might ask for another health care provider into whose hands I would want to entrust my life." Foreword by: Jeffrey B. Cooper, PhD Harvard Medical School, Boston, Massachusetts, July 2015 Identify and respond to a broad range of life-threatening situations with the updated Catalog of Critical Incidents, which outlines what may happen during surgery and details the steps necessary to respond to and resolve the crisis. React quickly to a range of potential threats with an added emphasis on simulation of managing critical incidents. Useful review for all anesthesia professionals of the core knowledge of diagnosis and management of many critical events. Explore new topics in the ever-expanding anesthesia practice environment with a detailed chapter on debriefing. Expert Consult eBook version included with purchase.

Pain in one form or another is probably the most common symptom presented to medical and healthcare professionals. Long a subject of biomedical interest, more recent biopsychosocial theories have extended the study of pain as a concept which is highly individual in the way it is experienced. Today s landscape offers a broad array of approaches to understanding pain and, crucially, to alleviating its impact. This concise and accessible volume aims to make sense of what is at first sight an eclectic mix of theoretical and practical work on pain, from a distinctly sociological perspective. While there has been much quantitative medical research on pain, in exploring sociology s important contributions to this field Elaine Denny offers insight into the world of those living with pain and the meaning it has in their lives. She provides readers with a range of explanations of pain and various influences on the experience of pain, critically analysing competing schools of thought and embedding this work in the everyday practice of providing care. The result is an illuminating volume for students of health and medical professions studying pain, the body, and the sociology of health and illness.

Part of the What Do I Do Now? Pain Medicine series, this timely volume presents clinical scenarios exploring headache medicine and treatments. Headache Medicine is a complex and constantly developing field, often relying on outdated and time-intensive textbooks. The purpose of this book is to educate readers on the diagnosis and management of commonly encountered headache disorders through brief discussion of relevant and specific cases. The book begins with Headache Medicine clinical pearls and red flags. It progresses through primary and secondary headache disorders, using cases to illustrate presentations and then help to guide an approach to evaluation and management. The book follows the same order as the International Classification of Headache Disorders (ICHD-3). Topics include migraines, cluster headaches, neuropathic eye pain, and trigeminal and occipital neuralgia. This handy guide will be of use to physicians and advanced practitioners (nurse practitioners and physician assistants) interested in the practice of Headache Medicine, emergency room and urgent care physicians, neurologists, internists, psychiatrists, physiotherapists, residents, and medical students undergoing a Neurology or Headache Medicine rotation.

Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.

A longtime standard for military healthcare personnel, the second edition of Military Advanced Regional Anesthesia and Analgesia Handbook (MARAA) has been thoroughly revised and updated. Although the MARAA handbook initially gained its reputation as a useful resource for managing pain associated with battlefield trauma, its beautifully illustrated step-by-step guidance provides pertinent and practical guidance for managing vital acute pain services in all civilian and military clinical settings. Opening chapters review equipment, local anesthesia and additives, and physics of ultrasound and nerve stimulation. Much of the book is devoted to step-by-step guidance on performing various regional anesthesia nerve blocks organized by pertinent neuroanatomy, use of nerve stimulation, and use of ultrasound. The concluding group of chapters discusses organization of the acute pain service and staff, a review of multidisciplinary care, basics of pediatric regional anesthesia, first-aid acupuncture, and more.

At its heart, Pelvic Pain Explained is the story of how patients develop pelvic pain, the challenges patients and providers face throughout the diagnosis and treatment process, the difficult task of sifting through the different available treatment options, and the impact that an "invisible" condition has on a patient's life and relationships, and much more. Those who develop pelvic pain find the path to proper diagnosis and treatment frustrating and unsuccessful, oftentimes because they are trying to work within the model of recovery they are used to; one in which they go to the doctor, maybe take some tests and then get a very specific diagnosis that dictates a very specific mode of treatment. This simply is not the path to healing from pelvic pain. Pelvic pain is a health issue that crosses the borders between medical disciplines and requires the patient to be a proactive participant in the healing process. Here, Stephanie Prendergast and Elizabeth Rummer offer readers guidance on navigating a pelvic pain diagnosis and treatment, helping them to better understand their pain from a physiological perspective as well as how to digest the current treatment options available and put them on the path to healing. Providers, too, will gain a better understanding of the effectiveness of an interdisciplinary treatment approach. Major topics the book tackles include: the anatomy of the pelvic floor with an explanation of the many ways pelvic pain occurs; the different diagnoses and contributing factors associated with pelvic pain; a discussion of the current treatment landscape with guidance on how to navigate it; the vital role that PT plays in treatment; male pelvic pain; pregnancy and pelvic pain; sex and pelvic pain; the role of the patient in healing; the role of the brain in pelvic pain; and much more. Anyone with pelvic pain will find here a starting point on the road to healing and living pelvic pain free.

Nunn's Applied Respiratory Physiology, Ninth Edition, is your concise, one-stop guide to all aspects of respiratory physiology in health, disease, and in the many physiologically challenging situations and environments into which humans take themselves - coverage is from basic science to clinical applications. Trusted for over 50 years, this most comprehensive single volume on respiratory physiology will prove invaluable to those in training or preparing for examinations in anaesthesia, intensive care, respiratory medicine or thoracic surgery - as well as an essential quick reference for physiologists and the range of practitioners requiring ready access to current knowledge in this field. Now fully revised and updated, this ninth edition includes a larger page format for improved clarity, as well as full access to the complete, downloadable eBook version. This incorporates BONUS chapters, handy topic summaries, interactive self-assessment material and a NEW series of expert lectures on key topics. The result is a more flexible, engaging and complete resource than ever before. Enhancements to this edition include: A new dedicated chapter on obesity - covering the effects of this global challenge on the physiology of the respiratory system in health and disease, in both adults and children Expanded coverage of the adverse effects of hyperoxia - including the physiology of the now popular technique of high-flow nasal therapy A revised section on air pollution - reflecting the growing importance and understanding of the impact of pollution on the lungs and other body systems, along with the latest worldwide guidelines Detailed coverage of artificial ventilation during general anaesthesia - covering post-operative respiratory complications and the physiological basis of current best-practice for optimizing ventilation Print comes with enhanced eBook - includes access to the complete, fully searchable text, PLUS: bonus chapters handy chapter summaries interactive self-assessment material a NEW series of 25 expert lectures focusing on the most essential topics in respiratory physiology

The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections.
Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true.
The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.