Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.

Answering questions such as 'how can I change my pain experience?', 'what is pain?', and 'how do nerves work?', this short research-based graphic book reveals just how strange pain is and explains how understanding it is often the key to relieving its effects. Studies show that understanding how pain is created and maintained by the nervous system can significantly lessen the pain you experience. The narrator in this original, gently humorous book explains pain in an easy-to-understand, engaging graphic format and reveals how to change the mind's habits to transform pain.

The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians and residents, this medical reference book will effectively prepare you to handle any critical incident during anesthesia. "A comprehensive discussion of the latest theories, principles and practices for CRM in perioperative practice and will be a useful resource for anaesthetists of all grades and levels of experience" Reviewed by British Journal of Anaesthesia, Jun 2015 "...this book contains essential information that all anesthesiologists should know or readily be able to easily reference..." Reviewed by Jane Torrie, Oct 2015 "Every anesthesia provider needs to study, not just read, this new edition, even if you read the first edition. Also, distilled instructions of key elements of the cases covered in this book need to be included in manuals made available for emergencies (although that, too, needs further study on how best to use them). If I were your patient, I would ask if you had studied these principles. If you hadn't, I might ask for another health care provider into whose hands I would want to entrust my life." Foreword by: Jeffrey B. Cooper, PhD Harvard Medical School, Boston, Massachusetts, July 2015 Identify and respond to a broad range of life-threatening situations with the updated Catalog of Critical Incidents, which outlines what may happen during surgery and details the steps necessary to respond to and resolve the crisis. React quickly to a range of potential threats with an added emphasis on simulation of managing critical incidents. Useful review for all anesthesia professionals of the core knowledge of diagnosis and management of many critical events. Explore new topics in the ever-expanding anesthesia practice environment with a detailed chapter on debriefing. Expert Consult eBook version included with purchase.

Welche Studienergebnisse entsprechen der besten wissenschaftlichen Evidenz? Erfahrene Herausgeber und Autoren stellen hier aktuelle Studienergebnisse nach EBM-Kriterien zusammen. Bereits nach kurzer Zeit in 2., komplett aktualisierter Auflage mit systematischer Gliederung der Inhalte nach den Bereichen Anasthesie und Intensivmedizin. Um viele praxisrelevante Themen erweitert u.a.: der kardiale Risikopatient, Transfusions-und Gerinnungsmanagement, Analgosedierung und Blutzuckermanagement auf der Intensivstation, intensivmedizinische Therapie der Pneumonie, COPD und des akuten Nierenversagens. Ein Werk, das arztliche Entscheidungen auf eine wissenschaftliche Basis stellt und aktuelle Studienergebnisse in den Klinikalltag integriert.

Accessible, concise, and clinically focused, Essentials of Pain Medicine, 4th Edition, by Drs. Honorio T. Benzon, Srinivasa N. Raja, Scott M. Fishman, Spencer S. Liu, and Steven P. Cohen, presents a complete, full-color overview of today's theory and practice of pain medicine and regional anesthesia. It provides practical guidance on the full range of today's pharmacologic, interventional, neuromodulative, physiotherapeutic, and psychological management options for the evaluation, treatment, and rehabilitation of persons in pain. Covers all you need to know to stay up to date in practice and excel at examinations - everything from basic considerations through local anesthetics, nerve block techniques, acupuncture, cancer pain, and much more. Uses a practical, quick-reference format with short, easy-to-read chapters. Presents the management of pain for every setting where it is practiced, including the emergency room, the critical care unit, and the pain clinic. Features hundreds of diagrams, illustrations, summary charts and tables that clarify key information and injection techniques - now in full color for the first time. Includes the latest best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Discusses recent global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, and identification of specific targets for molecular pain. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

The fifth edition of this popular textbook continues to provide a solid foundation of pharmacological knowledge for all those working in anaesthesia and intensive care. The content has been thoroughly revised to include expanded chapters with clearer figures, ensuring readers are kept abreast of the ever-changing landscape of clinical pharmacology. Conveniently divided into four sections covering the basic principles of pharmacology, core drugs in anaesthetic practice, cardiovascular drugs, and other important drugs and complemented by new diagrams, tables and chemical formulae to facilitate learning. All four chapters on core drugs in anaesthetic practice have been updated along with others exploring applied pharmacokinetic models, antimicrobials, and drugs used in diabetes. An ideal aid to study and practice for junior and trainee anaesthetists and intensive care specialists preparing for exams. Also an invaluable resource for theatre practitioners, ICU nurses and physicians working in areas that demand a solid knowledge of pharmacology.

While recognizing the multidisciplinary nature of pain management, the Clinical Manual of Pain Management in Psychiatry focuses on the role of mental health practitioners in evaluation and assessment, pharmacological management, psychotherapeutic interventions, and comprehensive treatment planning. It balances theoretical foundations of pain pathophysiology with applied clinical information, providing guidelines to psychiatric differential diagnosis of pain states and psychiatric comorbidities associated with pain and integrating diagnostic and treatment approaches. Because proper treatment requires understanding the whole person, the book views the patient from biological, psychological, and social perspectives. It stresses the importance of examining psychological variables that can limit outcomes and even preclude aggressive interventional approaches. The manual also includes considerations pertinent to the elderly, children, and cultural groups.

This manual expands on the author's previous Concise Guide to Pain Management for Psychiatrists to reflect significant advances in the field of pain medicine. It updates trends in treatment approaches along with our understanding of chronic pain conditions, and presents new knowledge of the biological substrates underlying both pain and psychiatric comorbidities. The manual features particularly extensive revisions regarding the use of psychiatric and other adjunctive medications in pain management, including expanded discussion of long-term adverse effects, dependence, and pseudoaddictive behaviors involving opiates and weak analgesics. It also delineates the use of adjunctive treatments, including evolving data on the use of antidepressants and related medications for patients with chronic pain. Among the its practical benefits, the book - Features updated coverage of common psychiatric comorbidities such as depression, anxiety, and personality disorders- Addresses common pain disorders ranging from headache and back pain to pain related to cancer and HIV- Includes an extensively revised chapter on pharmacology, familiarizing readers with the range of pain medications and providing information on dosages and side effects- Fully discusses psychotherapeutic approaches, plus adjunctive interventions such as biofeedback and hypnosis - Covers special techniques such as acupuncture and regional neural blockade- Offers updated advice on emerging forensic issues, from disability claims to controlled substance diversion

With pain management issues so common in daily practice, this handy portable guide is designed for quick reference, features numerous tables and illustrations, and is easily understandable by less experienced clinicians or non-pain specialists. While written expressly for busy psychiatrists, it is also useful to psychologists, social workers, and other physicians.

A longtime standard for military healthcare personnel, the second edition of Military Advanced Regional Anesthesia and Analgesia Handbook (MARAA) has been thoroughly revised and updated. Although the MARAA handbook initially gained its reputation as a useful resource for managing pain associated with battlefield trauma, its beautifully illustrated step-by-step guidance provides pertinent and practical guidance for managing vital acute pain services in all civilian and military clinical settings. Opening chapters review equipment, local anesthesia and additives, and physics of ultrasound and nerve stimulation. Much of the book is devoted to step-by-step guidance on performing various regional anesthesia nerve blocks organized by pertinent neuroanatomy, use of nerve stimulation, and use of ultrasound. The concluding group of chapters discusses organization of the acute pain service and staff, a review of multidisciplinary care, basics of pediatric regional anesthesia, first-aid acupuncture, and more.

With a fresh approach to a common problem, this self-help guide to overcoming back pain advocates adopting the natural, healthy posture of athletes, young children, and people from traditional societies the world over. Arguing that most of what our culture has taught us about posture is misguided--even unhealthy--and exploring the current epidemic of back pain, many of the commonly cited reasons for the degeneration of spinal discs and the stress on muscles that leads to back pain are examined and debunked. The historical and anthropological roots of poor posture in Western cultures are studied as is the absence of back pain complaints in the cultures of Africa, Asia, South America, and rural Europe. Eight detailed chapters provide illustrated step-by-step instructions for making simple, powerful changes to seated, standing, and sleeping positions. No special equipment or exercise is required, and effects are often immediate.

Back problems are the leading cause of disability worldwide - and many of us will endure severe or chronic back pain at some time in our lives. But what can we do? Are surgery and painkillers the only answers? "Not at all," says spine and neck expert Dr. Ken Hansraj. "There are dozens of exercises, habits, and techniques you can practice - anytime, anyplace - that will significantly improve, if not completely heal, your back pain." Now, this leading researcher presents a comprehensive guide to help you overcome physical, mental, and emotional factors that contribute to back problems. In Watch Your Back, Dr. Hansraj offers a straightforward program for taking the health of your spine and neck into your own hands. Here he offers nine adoptable strategies that provide simple, specific directions on what to do to strengthen your back and make your spine supple. With guidance on nutrition, posture fixes, mindfulness practices for positivity, stretches, and more, Dr. Hansraj's program has provided healing and pain relief for hundreds of patients. "The health of our back is essential to our overall wellness - not just our physical health, but our clarity of mind, emotional balance, and quality of life," says Dr. Hansraj. Here is an essential resource for anyone suffering from back issues - with powerful self-care methods to help you recover the joy and freedom of a healthy spine.

Career or Fibromyalgia, Do I Have to Choose? sorts out all the symptoms that are keeping sufferers of fibromyalgia in a cycle of confusion and unable to work. Karen R. Brinklow is the first Certified Fibromyalgia Advisor in Canada, returned to the dream career she thought was over because of fibromyalgia. Throughout Career or Fibromyalgia, Do I Have to Choose?, she shows sufferers how they can too. Karen partners with those suffering from fibromyalgia to take action now and: Reduce pain and fatigue so they feel less confused and frustrated Stop searching for answers so they can gain focus and feel organized Figure out which symptoms to tackle first so they can enjoy life Manage their symptoms and make a plan to return to the job they love Those suffering from fibromyalgia do not have to live like this anymore and do not have to give up the career they love. It's time to get back to work and off the hamster wheel of pain, exhaustion, fuzzy thinking, and stiffness.

The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections.
Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true.
The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

Anaesthesia at a Glance is a brand new title that provides a concise and visually-orientated summary of a comprehensive lecture course in anaesthesia. Ideal for clinical undergraduate medical students and Foundation Programme doctors undertaking anaesthesia attachments, it gives a systematic, broad view of anaesthesia in various specialties, taking the reader through preparation, management and the pharmacology behind anaesthetic medicine. Anaesthesia at a Glance is supported by a companion website at www.ataglanceseries.com/anaesthesia containing interactive multiple-choice questions and answers together with a selection of interactive cases - perfect for study and revision. Whether you want to refresh your knowledge or need a thorough overview of the specialty, Anaesthesia at a Glance presents all the vital clinical information you need.

This updated second edition of Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care contains the ideal combination of updated information for the practitioner, presented in easy-to-digest short chapters. With an essential clinical focus on key neuroanesthesia and neurointensive care knowledge, it is a practical guide for any practitioner of neuroanesthesia, beginner, occasional or experienced. The user-friendly format contains bullet points to ensure retention of important data, key points to summarize the take-home messages, suitable images to enhance understanding, and pertinent and appropriate references to allow for further exploration of the topics. This book is ideal for residents and others undergoing neuroanesthesia training. It is also a great tool for Operating Room nurses and other OR support workers, neurosurgical residents and neurointensive care professionals. This will also be a useful book to supplement knowledge for postgraduate fellowship and Board examinations.

Are you frustrated by the lack of lack of quality, up-to-date revision material for the Primary FRCA OSCE examination? The answer is here. Primary FRCA: OSCEs in Anaesthesia provides candidates with over 80 practice OSCE stations presented in the style of the Royal College exam. Covering the main OCSE categories such as physical examination, resuscitation and simulation, anaesthetic hazards, and equipment, this book will help candidates prepare for the exam and test their knowledge. Each station is constructed in clear and logical fashion to make the revision of individual topics more accessible. The sample questions and answers allow self-testing and are complemented by discussions, numerous illustrations and up-to-date clinical guidelines which follow modern-day anaesthetic practice. With more candidates now failing the OSCE component of the exam, Primary FRCA: OSCEs in Anaesthesia is a must-have for trainees and tutors preparing for the primary FRCA.

This volume will provide the reader with a good general understanding of human physiology, giving them the tools needed to apply physiological principles and knowledge to the clinical practice of anaesthesia.

This book provides an original account of behavioral aspects with important ramifications for the study of transient receptor potential (TRP) channels functioning. It explains, in terms of specified somato-sensory mechanisms and systems, how TRP channels work. Through exploration of animal models by testing paw withdrawal reflexes to thermal and mechanical stimuli, it is shown that TRP channels are promising targets for the development of a new group of analgesic drugs at the periphery and central levels and opportunities for therapeutic intervention.

Neuropuncture is the clinical manual of a groundbreaking acupuncture system that incorporates neuroscience into its clinical applications for pain management, orthopaedic conditions and internal medicine. It shows acupuncturists how to apply research into the neurophysiological mechanisms of acupuncture and electrical acupuncture to the traditional TCM model of healthcare. The book explains how acupuncture works using Western medical science and illustrates how to apply this knowledge to clinical cases with electrical acupuncture, creating evidence-based acupuncture protocols. These protocols are clinically proven and result in reproducible clinical outcomes.

As the practice of obstetric anesthesia becomes increasingly recognized as a major subspecialty of anesthesia, there is a growing interest from current practitioners to evolve their neuraxial, regional, and general anesthesia techniques and understanding of the latest evidence. Obstetric Anesthesia Practice is a timely update in the field, providing a concise, evidence-based, and richly illustrated book for students, trainees, and practicing clinicians. Comprehensive in scope, this book addresses the essential topics necessary for the practitioner to quickly assess the patient and risk stratify them, decide on the type of analgesic and anesthetic plan most appropriate as well as its feasibility and safety, provide expert consultation to the other members of the obstetric team, manage anesthesia care and complications, and arrange for advanced care if needed.

The perioperative care of individuals with neurologic compromise is critically important, yet it is only one dimension of the rich relationship between anaesthesiology and the neurosciences. The mechanism of everyday therapeutic interventions such as anaesthesia and analgesia is exciting neuroscience in its own right. At the new frontier of outcomes studies lies the question of how the perioperative period might impact the brain. For example, questions related to anaesthetic neurotoxicity, delirium, and cognitive dysfunction pose critical challenges for the field. The Oxford Textbook in Neuroscience and Anaesthesiology addresses the exciting field of neuroanaesthesiology in a new and stimulating way. In twenty eight chapters, the neuroscientific basis of anaesthesiology, the full spectrum of clinical neuroanaesthesia, and the care of neurologic patients undergoing non-neurologic surgery are explored in one comprehensive textbook for the first time. The first section considers the neural mechanisms of general anaesthetics, cerebral physiology, the neurobiology of pain, and more. The second section explores the care of patients with neurologic disease in the operating room or intensive care unit. These clinical chapters systematically treat the perioperative considerations of both brain and spine surgery, and provide introductions to neurocritical care and pediatric neuroanaesthesia. The final section outlines the care of neurologic patients undergoing non-neurologic surgery. It examines key connections of neurology and anaesthesiology, examining how conditions such as dementia, stroke, or epilepsy interface with the perioperative period. Each chapter has been carefully crafted to be concise yet highly informative, reflecting the cutting edge of neuroscience and neuroanaesthesiology. This international textbook gathers the best available expertise of authors and leaders worldwide. Includes access to online-only content, including more than 20 cases and more than 90 questions that can be used in presentations and teaching sessions. By activating your unique access code, you can access and use the material.

Trigeminal neuralgia and other cranial neuralgias comprise a group of facial pain conditions, characterised by disabling pain attacks that selectively respond to specific treatments. Although not as common migraine, they affect over 1% of the population and must be recognised and adequately treated in clinical practice. The spectrum of cranial neuralgias is wide and as a consequence the conditions are managed by a range of different specialists. Studies show that delayed diagnoses and mismanagement are common and can lead to depression and suicide. 36 recognised experts from nine countries have contributed to OPML Trigeminal Neuralgia and Other Cranial Neuralgias to guide you through the maze of pathophysiology, clinical features, diagnosis-making, and condition-specific treatments. The approach is practical and evidence-based and ready for real-world applications. The value of phenotyping, targeted investigations, and treatment algorithms is emphasised. The editors and contributors subscribe to the view that there needs to be a holistic approach with multidisciplinary teams working together and with patients being at the centre of this process. Psychologists and patent support groups can help to ensure that patients are managed holistically and share the decision-making process. Their involvement in the handbook has helped to emphasis this. There remain considerable challenges, but the field is rapidly evolving and there are increasing number of opportunities opening up to improve our understanding of these conditions and hence their management. The editors and contributors have included case scenarios, algorithms, self-administered tools for training in diagnosis and management, clinical tips and carefully chosen references. Each chapter includes a lay summary and key points and can be read as a stand-alone unit.

This second edition of Clinical Pediatric Anesthesia: A Case-Based Handbook offers a comprehensive review of the options, advantanges, and disadvantages of different aspects of the perioperative management of the pediatric patient, as well as examples of a wide range of relevant clinical scenarios. Chapters are organized into 15 sections and cover the field of pediatric anesthesiology with a point-of-care approach. Written by a team of over 50 Pediatric Anesthesiologists at tertiary children's hospitals, this highly accessible text provides readers with multiple approaches to the anesthetic care of the pediatric patient. Each chapter includes an introduction to the topic, followed by learning objectives, clinical vignettes, and a discussion section styled in a question-and-answer format, concluding with a summary of the highest-yield and most salient information. Chapters also provide annotated references and suggestions for further reading to facilitate in-depth study of topic. The variety of cases presented, along with the contributors' expertise, render valuable real-life clinical situations that promote critical thinking and evaluation necessary for all pediatric anesthesiology consultants.

Chronic illness and pain are now, more than ever, seen asas major problems in the current health care system. Because they are unresponsive to both antibiotics and surgery, theyr are seen as elusive and mysterious. The National Medical Expenditure Survey estimates that over 80 million U.S. citizens live with a chronic illness. The most prevalent are arthritis, diabetes, respiratory diseases, hypertension and mental illness. This book uses the novel Robinson Crusoe as an archetypal metaphor for the patients who must learn to survive on their own isolated "island" of chronic pain. This unique style is combined with a variety of in-session approaches and other tools which clients have found helpful in identifying their goals and progress. By emphasizing the importance of self-care the authors hope to diminish the sense of helplessness felt by the both the patients their loved ones.