It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emphasis shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and tumor suppressor genes function in the same pathways, providing positive and ne- tive growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell biology, including nuclear events, cell cycle, cell death, cytoskeletal, cell membrane, angiogenesis, and cell adhesion effects. Tumor suppressor genes are mutated in hereditary cancer syndromes, as well as somatically in nonhereditary cancers. In their normal state, TSGs control cancer development and p- gression, as well as contribute to the sensitivity of cancers to a variety of therapeutics. Understanding the classes of TSGs, the biochemical pathways they function in, and how they are regulated provides an essential lesson in cancer biology. We cannot hope to advance our current knowledge and to develop new and more effective therapies without understanding the relevant pathways and how they influence the present approaches to therapy. Moreover, it is important to be able to access the powerful tools now available to discover these genes, as well as their links to cell biology and growth control.

The woods are full of puzzles to be solved, clues to be found. Inspired by this books hints and fun-filled experiments and activities, and using only simple equipment, young readers unlock the closely guarded secrets of the woods­­from the strange meetings of lazy butterflies, to the miraculous walking of a twig, to the riddle of why the leaves turn color and fall. One small square at a time, these detectives plunge deeper and deeper into ancient mysteries­­without ever getting lost. Beautifully illustrated, Woods offers a picture field guide, a glossary-index, and a resource list.

This fantastic CGP Revision Guide is perfectly matched to the Higher Level Grade 9-1 Edexcel GCSE Biology course. Every topic is explained with clear, succinct study notes, examples and diagrams - and there are practice questions at the end of every page to test you on what you've learned (with answers and mark schemes included). We've covered all the crucial new elements of the Grade 9-1 course, including the required practicals, maths skills and Working Scientifically. What's more, a free Online Edition of the whole book is included - just use the unique access code printed inside the cover to access it on a PC, Mac or tablet! And to make sure you're 100% prepared for the final exams, a matching Biology Exam Practice Workbook is also available from CGP - see 9781782944959.

Exam Board: SQA Level: S1-N4 Subject: Biology Bring biology to life with this exciting new resource for S1-S3 classrooms! Provides in-depth coverage of Third Level and Fourth Level as well as National 3 and National 4 Keep mixed level teaching simple with a single Student Book per subject Different levels clearly labelled for ease of use, especially helpful when working with mixed level groups One textbook per science will cover your teaching needs for three years Interesting and rich classroom activity and homework ideas tied to CfE that will give pupils a sense of progress and excitement Plentiful assessment exercises referenced to the relevant qualification

Covering all GCSE specifications, this tried and tested series has been fully updated to match the (9-1) GCSE Biology specifications for first examination in 2018, as well as international specifications. With a focus on science, concepts develop naturally, engaging students and enabling them to get a thorough understanding of Biology.

Have you ever heard of a reptile that spends most of its life in an egg? What about a reptile that has to lay its eggs on the same beach where it was hatched? In this book, young readers will learn all about Madagascar chameleons, sea turtles and other reptiles with unusual life cycles.

With big eyes and ears and colourful bodies, a lot of creatures in nature can look very cute. But don't always be fooled by their adorable appearance. When provoked, these animals can easily injure or kill a person. Their defence mechanisms, such as poison or sharp teeth and claws, can turn them from darling to deadly in seconds. Get ready to discover some of the world's cutest killers!

With their eerie howls and fierce hunting skills, wolves are fascinating creatures. These loyal pack animals are close relatives to man's best friend, dogs. Learn more about these proud hunters.

The Effective Teaching of Biology aims to identify the special dimensions of the subject, how it contributes to the curriculum as a whole and why the teaching of biology differs from the teaching of other subjects. Current legal and safety requirements are provided together with practical teaching ideas and sources of information. The book also covers contemporary issues which are the subject of extensive debate, such as the changing patterns of assessment of pupils, the use of living organisms in school and the nature of learning difficulties which pupils experience.

This indispensable CGP Exam Practice Workbook is packed with hundreds of exam-style questions (including worked answers) for the Grade 9-1 Edexcel International GCSE Biology exams - and it's great for the Biology parts of International GCSE Double Award Science too. Every question is labelled with a grade range on the 9-1 scale, so it's easy for students to focus practice on the difficulty level that suits them best. The book is rounded off with two mock exam papers to help make sure they're 100% prepared for the real thing. Study notes for the whole course are available in our matching Revision Guide (9781782946748).

There's a new baby joining the family. It's a cheetah cub! Learn all about baby cheetahs, including what they eat, what they weigh, how they're raised and how big they grow.

Author/Illustrator April Chloe Terrazas continues with Book 5 of the Super Smart Science Series, sharing an in depth look at bones and muscles for kids. Candy colored illustrations are combined with simplified text and pronunciation guides in this upbeat, textbook-like guide. Beginning with the skeleton, continuing with bone anatomy (compact bone KOM-PAKT BONE, periosteum PER-EE-OS-TEE-UM, osteon OS-TEE-ON, spongy bone SPUN-JEE BONE, marrow MER-OH), the reader is brought face to face with the intriguing way our bodies are made. After a thorough look at bones and a review to reinforce the material, skeletal, cardiac and smooth muscles are explored, beginning with their physical appearance (striated or not), to where they are found in the body. Terrazas takes you even further into understanding how the body moves, combining the previously learned material on bones, muscles, tendons and ligaments and fusing it with the active role of the neuron in the neuromuscular junction Enjoy learning with Book 5 of the Super Smart Science Series.

Have you ever heard of a mammal that lays eggs? What about a mammal that can give birth to 50 babies at once? In this book, young readers will learn all about echidnas, Tasmanian devils and other mammals with unusual life cycles.

This Tutor Delivery Pack for AQA GCSE (9-1) Biology Higher has a curriculum that matches tutor packs for a whole academic year and contains everything needed for a whole academic year of private tutoring: 38 complete lessons, complete with plans, activities and homework Detailed explanation on the use of the pack Information for parents Specification guidance Needs analysis for the parents and the students Mapping guide to the Revise GCSE Series Progress and End-of-Lesson Report templates Differentiation and extension ideas Customisable certificates in the digital version of the pack

When it comes to Grade 9-1 GCSE Biology exam prep, nothing beats good old-fashioned practice. This Exam Practice Workbook is bursting with realistic exam-style questions for the entire AQA course (Foundation level), including coverage of Working Scientifically, AO3 practical skills and all the required practical activities. Every question is labelled with a grade, so it's easy for students to tailor their practice for their target grade or focus on the tough stuff! Full answers are available in a separate answer book (9781789083279). What's more, we've also put together some free "What to Expect in the Exam" information, available via a link in the book! For the perfect revision combo, check out our matching AQA GCSE Biology Foundation level Revision Guide (9781789083248).