This collection traces the intersection between writing and intoxication, from the literary to the theoretical, exploring a diversity of experiences of excess. Comprising a variety of perspectives, this book offers unique insights into how politics and literature have been shaped by states of intoxication.

Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have been made in characterizing the clinical pharmacology of cocaine, and those advances have been extended to understanding individual vulnerability to cocaine abuse, development of effective treatments, and discussions of policy. Those advances are critically reviewed in the third section of this volume. Contributors to the book were selected because of their status as internationally recognized leaders in their respective areas of scientific expertise. Moreover, each is a proponent of the importance of a rigorous, interdisciplinary scientific approach to effectively addressing the problem of cocaine abuse. As such, this volume offers a coherent, empirically-based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas. Each of the specific chapters is sufficiently detailed, in-depth and current to be valuable to informed readers with specific interests while also offering a comprehensive overview for those who might be less informed or have broader interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse in general.
Key Features
* Discusses cocaine abuse within the context of current principles of psychology, pharmacology, neuroscience, genetics and epidemiology
* Chapters are all authored by scientific experts
* First of its kind book on cocaine abuse to recognize behavioral/environmental determinants
* Coverage is comprehensive
* Informative for experts and generalists alike

While citizens experiment with illegal drugs, their governments experiment with regulations to prohibit drugs. Scholars, analysts, and policy makers who know what legal prohibitions other countries have tried and found successful will have a better chance of crafting effective drug policy for their countries. This special issue of "The Annals" describes the experiences of eleven countries: Australia, Canada, Columbia, Denmark, France, Iran, Jamaica, Mexico, Portugal, Russia, and Sweden. Articles are grouped by geography and wealth: the wealthy West, the western hemisphere, and the transition countries.

The drug problems of wealthy Western nations have generally worsened since the 1960s. Some have no clearly articulated vision behind their drug policy (e.g. Denmark); others have tough policies (e.g. Sweden). France and Portugal both recently instituted sharp changes in drug policy. While no outcome results are yet available from Portugal, France has experience a huge increase in the number of users in treatment. Australia s strong harm-reduction policy remains in place despite increasing heroin deaths and other drug-related problems.

U.S. consumption and U.S. international drug policies affect western hemisphere countries policy as well as generate problems for them. Although Mexican drug use remains at modest levels, the country faces violent and powerful criminal groups. The groups creation is related to Mexico s role as the principal source and primary transshipment route for drugs bound for the U.S. IN Jamaica, another route for cocaine shipped to the U.S. and another focus of U.S. international drug policy, drug trafficking has exacerbated the long-standing problem of politically related gang violence by increasing the moneys and weapons involved. Drug use is a relatively minor concern of Columbian policy, also under U.S. pressure; instead, it focuses on trafficking and related corruption and violence.

Iran and Russia are countries in transition. Contending with fundamental economic and social change following the collapse of the Soviet Union, Russia has had little political debate regarding its highly intolerant drug policy. Iran s drug policies have frequently shifted during its long history of dealing with opiate abuse, from harsh punishment to regulation of use and back again. Most recently, more therapeutically oriented approaches have been tried.

Two articles address geographically broader issues. One shows how U.S. politicians distorted results from a study of needle exchange in Vancouver. The other discusses creation of a new regulatory regime for governing developed nations banking systems, in the belief that illegal drugs account for a substantial fraction of suspicious financial transactions, particularly across national borders. "

The place of drugs in American society is a problem more apt to evoke diatribe than dialog. With the support of the Na tional Science Foundation's program on Ethics and Values in Science and Technology, and the National Endowment for the Humanities' program on Science, Technology, and Human Values, * The Hastings Center was able to sponsor such dialog as part of a major research into the ethics of drug use that spanned two years. We assembled a Research Group from leaders in the scientific, medical, legal, and policy com munities, leavened with experts in applied ethics, and brought them together several times a year to discuss the moral, legal and social issues posed by nontherapeutic drug use. At times we also called on other experts when we needed certain issues clarified. We did not try to reach a consensus, yet several broad areas of agreement emerged: That our society's response to nontherapeutic drug use has been irrational and inconsistent; that our attempts at control have been clumsy and ill-informed; that many complex moral values are entwined in the debate and cannot be reduced to a simple conflict between individual liberty and state paternalism. Of course each paper should be read as the statement of that particular author or authors. The views expressed in this book do not necessarily represent the views of The Hastings Center, the National Science Foundation, or the National En dowment for the Humanities."

This volume is devoted to descriptions of non medical as well as medical uses for some drugs that have typically, or not so typically, been associated with drug abuse. One major objective of this book is to identify costs and benefits of drug abuse. The book highlights drugs including 3,4 methylenedioxymethamphetamine (MDMA), cannabinoids, opioids and methylphenidate because of their well-documented potential for abuse and provides new and emerging evidence of their potential to treat some chronic disease states alongside the potential consequences of exposure.

What do psychedelics reveal about consciousness? What impact have psychedelics had on philosophy? In this rapidly growing area of study, this is the first volume to explore the philosophy of psychedelic experience, from a range of interdisciplinary and cross-cultural perspectives. In doing so, Philosophy and Psychedelics reveals just why the place of psychedelics in our societies should not be left to medical sciences alone, as psychedelic experience opens up new perspectives on fundamental philosophical questions relating to human experience, ethics, and the metaphysics of mind. Mapping a range of philosophical responses to the surge in studies into psychedelic drugs in the cognitive sciences, this go-to volume examines topics including psychedelics and the role of governance; psychedelics and mysticism; what psychedelics can tell us about dyadic thankfulness; and psychedelics as ways to gain new knowledge. Written by leading international scholars, the essays cover Western and non-Western traditions, from analytic philosophy to Zen Buddhism, and discuss a variety of hallucinogens, such as LSD, MDMA, and Ayahuasca, in order to build a much-needed bridge between the rapidly growing scientific research and the philosophy behind psychedelic experience.

THE NO. 1 NEW YORK TIMES BESTSELLER, NOW A MAJOR NEW NETFLIX SERIES 'Reminds us that the mind is the greatest mystery in the universe' Yuval Noah Harari, Guardian, Books of the Year Could psychedelic drugs change our worldview? Join Michael Pollan on a journey to the frontiers of the human mind. Diving deep into an extraordinary world - from shamans and magic mushroom hunts to the pioneering labs mapping our brains - and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of consciousness. 'A sweeping and often thrilling chronicle of the history of psychedelics, all interwoven with Pollan's adventures as a psychedelic novice. This is a serious work of history and science, but also one in which the author, under the influence of toad venom, becomes convinced he's giving birth to himself' Oliver Burkeman, Guardian 'A mind-altering book ... full of transformations' Richard Godwin, Evening Standard 'An irresistible blend of history, research and personal experience. In terms of the psychedelic wave, the book is the big kahuna, the Big Bang moment for a movement that is gathering force' John McKenna, Irish Times 'Entertaining and engrossing' Paul Laity, Financial Times 'Deeply absorbing, wise and beautifully written' Mick Brown, Literary Review 'An astounding book' Andrew Sullivan, New York Magazine

The practice of yoga, hypnosis, and the use of psychedelic drugs to alter psychological and physiological states is not unknown to the study of psychology. They have been called "soft" studies and labeled unimportant. This is mostly because they are difficult to study and understand, often focusing on unobservable internal states such as altered states of consciousness, Samadhi, or hypnotic states. This book, in its approach to thinking about this topic and method for analysis, focuses only on phenomena that can be observed, such as behavioral changes.

By centering on only those aspects of the psychological and physiological effects of yoga, hypnosis, and psychedelic drugs which can be measured and analyzed using this new method, Barber distinguishes this book from others in the field. He asks what overt behaviors and verbal reports are clearly observable when psychedelic drugs are taken, yoga is practiced, or hypnotic-induction procedures are administered. Instead of treating the phenomena traditionally associated with psychedelic drugs, yoga, or hypnosis as undifferentiated conglomerates, an attempt will be made to set apart and treat separately each of the many phenomena associated with each of these areas of inquiry.

This book does not set out to simply demonstrate the importance of psychedelics, yoga, and hypnosis, or to present substantive material pertaining to these topics. It also treats each topic as continuous with other known psychological phenomena and as an important piece to the puzzle of social psychology. It differs from most previous treatises in that it does not assume that psychedelics, yoga, and hypnosis can bring out unused mental or physical capacities in man, heighten awareness or give rise to enhanced creativity, or produce altered states of consciousness, suspension of conventional reality-orientation, changes in body-image, or changes in perception.

THE INSPIRATION FOR THE MAJOR NEW NETFLIX SERIES, HOW TO CHANGE YOUR MIND 'It's a trip - engrossing, eye-opening, mind altering' New Statesman 'Fascinating. Pollan is the perfect guide ... curious, careful, open minded' The Guardian Of all the many things humans rely on plants for, surely the most curious is our use of them to change consciousness: to stimulate, calm, or completely alter the qualities of our mental experience. In This Is Your Mind On Plants, Michael Pollan explores three very different drugs - opium, caffeine and mescaline - and throws the fundamental strangeness of our thinking about them into sharp relief. Exploring and participating in the cultures that have grown up around these drugs, while consuming (or in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants, and the equally powerful taboos. In a unique blend of history, science, memoir and reportage, Pollan shines a fresh light on a subject that is all too often treated reductively. In doing so, he proves that there is much more to say about these plants than simply debating their regulation, for when we take them into our bodies and let them change our minds, we are engaging with nature in one of the most profound ways we can. This ground-breaking and singular book holds up a mirror to our fundamental human needs and aspirations, the operations of our minds and our entanglement with the natural world.

Originally published in 1980, this book presents a detailed account of a series of investigations that examined the patterns of resort to drugs and alcohol use in college youth, and how such substance uses are linked to personality characteristics and daydreaming patterns. The Editors chose to emphasize the more "private" features of the personality, because these had often been ignored in earlier research, despite popular assumptions that there are close ties between fantasy, inwardness, "spacey" qualities (all suggesting permanent changes in mental organization), and substance use in youth. This volume will be of interest to a wider audience than just drug and alcohol researchers, because of the effort to go beyond normative patterns of substance use toward explorations of personality and consciousness.

Electronic dance music was once the utopian frontier of pop culture. But three decades after the acid house 'summer of love', it has gone from subculture to the global mainstream. Does it still have the same power to inspire?

From the pleasure palaces of Ibiza and Las Vegas to 'new frontiers' like Shanghai and Dubai, raving is now a multi-million-dollar business. But there are still hardcore believers upholding its DIY ethos - the techno idealists of Berlin and Detroit and the queer subcults of New York, the post-apartheid party people of South Africa and the outlaw techno travellers of France.

In Rave On, Matthew Collin travels the world to experience these unique scenes first-hand, talk to the key players and hear the story of how dance culture went global - and find out if its maverick spirit can survive its own success.

This book depicts how Freud's cocaine and Benjamin's hashish illustrate two critiques of modernity and two messianic emancipations through the pleasures of intoxicating discourse. Freud discovered the "libido" and "unconscious" in the industrial mimetic scheme of cocaine, whereas Benjamin found an inspiration for his critique of phantasmagoria and its variant psychoanalysis in hashish's mimesis. In addition, as part of the history of colonialism, both drugs generated two distinct colonial discourses and, consequently, two different understandings of the emancipatory powers of pleasure, the unconscious, and dreams. After all, great ideas don't liberate; they intoxicate.

Often, people use nicotine, caffeine, and some level of alcohol in varying combinations at different times of the day in order to optimize their functioning and feelings of well-being, whether at work, in leisure time, or in a social context. However, until now, studies on the effects of this everyday practice have been diverse, widespread, and insufficiently summarized. Recently developed methods to study the effects in more detail have received little attention, especially among a nonscientific readership. Nicotine, Caffeine and Social Drinking focuses readers' attention on the effects of normal, socially accepted psychoactive substances on cognitive performance and on the brain. Divided into three sections, this book studies each substance individually before examining the effects of their combined usage.

A gripping investigation that opens fresh perspectives on biology and anthropology 'At the cutting edge of contemporary thought' GUARDIAN 'A thoroughly enjoyable read' SUNDAY TELEGRAPH While living among Peruvian Indians, anthropologist Jeremy Narby became intrigued by their claim that their phenomenal knowledge of plants and biochemistry was communicated to them directly while under the influence of hallucinogens. Despite his initial scepticism, Narby found himself engaged in an increasingly obsessive personal quest. The evidence he collected - on subjects as diverse as molecular biology, shamanism, neurology and ancient mythology - led inexorably to the conclusion that the Indians' claims were literally true: to a consciousness prepared with drugs, specific biochemical knowledge could indeed be directly transmitted through DNA itself. A gripping investigation that opens fresh perspectives on biology, anthropology and the limits of rationalism, The Cosmic Serpent is new science of the most exhilarating kind.

Can psychedelic drugs help us tackle the biggest problems we face globally? Can they heal the cultural, spiritual, and political wounds we’re wrestling with? Psychedelics have hit the mainstream as powerful new mental health treatments. But as clinicians explore what these molecules can do for our individual minds, The Bigger Picture goes further to illuminate how psychedelics can help us find new ways to make sense of and come through the crises we face around the world. Drawing on the latest research, as well as his unique experience as a participant in a ground-breaking clinical trial investigating the potent psychedelic DMT, Alexander Beiner reveals: - the role of psychedelics in addressing global issues such as global warming, geopolitical instability, and political polarization - the dark side of the ‘psychedelic renaissance’ and ‘psychedelic capitalism’ - what it takes to elicit huge personal and cultural transformation through psychedelics Embark on a journey into The Bigger Picture – a new era of science and spirituality with the potential to radically transform our perceptions of ourselves, one another, and our life on this planet.

Back in print after 20 years, this text from the earliest days of psychedelia chronicles the experiences on 16 acid trips taken before LSD was illegal. The trip guides or "high priests" included Aldous Huxley, Ram Dass, Ralph Meltzner, Huston Smith and a junkie from New York City named Willy. It tells of the goings-on and freaking out at the Millbrook mansion in New York State that became the Mecca of psychedelia during the 1960s, and of the many luminaries who made their pilgrimage there to trip with Leary and his group. Chapters include an I Ching reading and a chronicle of what happened during those "spacewalks" of the mind.

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely in controlled conditions, and can cause lasting psychological benefits with one or two administrations. Supervised psychedelic sessions can reduce symptoms of anxiety, depression, and addiction, and improve well-being in healthy volunteers, for months or even years. But these benefits seem to be mediated by "mystical" experiences of cosmic consciousness, which prompts a philosophical concern: do psychedelics cause psychological benefits by inducing false or implausible beliefs about the metaphysical nature of reality? This book is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism. Within the book, Letheby integrates empirical evidence and philosophical considerations in the service of a simple conclusion: this "Comforting Delusion Objection" to psychedelic therapy fails. While exotic metaphysical ideas do sometimes come up, they are not, on closer inspection, the central driver of change in psychedelic therapy. Psychedelics lead to lasting benefits by altering the sense of self, and changing how people relate to their own minds and lives-not by changing their beliefs about the ultimate nature of reality. The upshot is that a traditional conception of psychedelics as agents of insight and spirituality can be reconciled with naturalism (the philosophical position that the natural world is all there is). Controlled psychedelic use can lead to genuine forms of knowledge gain and spiritual growth-even if no Cosmic Consciousness or transcendent divine Reality exists. Philosophy of Psychedelics is an indispensable guide to the literature for researchers already engaged in the field of psychedelic psychiatry, and for researchers-especially philosophers-who want to become acquainted with this increasingly topical field.

The practice of yoga, hypnosis, and the use of psychedelic drugs to alter psychological and physiological states is not unknown to the study of psychology. They have been called "soft" studies and labeled unimportant. This is mostly because they are difficult to study and understand, often focusing on unobservable internal states such as altered states of consciousness, Samadhi, or hypnotic states. This book, in its approach to thinking about this topic and method for analysis, focuses only on phenomena that can be observed, such as behavioral changes.

By centering on only those aspects of the psychological and physiological effects of yoga, hypnosis, and psychedelic drugs which can be measured and analyzed using this new method, Barber distinguishes this book from others in the field. He asks what overt behaviors and verbal reports are clearly observable when psychedelic drugs are taken, yoga is practiced, or hypnotic-induction procedures are administered. Instead of treating the phenomena traditionally associated with psychedelic drugs, yoga, or hypnosis as undifferentiated conglomerates, an attempt will be made to set apart and treat separately each of the many phenomena associated with each of these areas of inquiry.

This book does not set out to simply demonstrate the importance of psychedelics, yoga, and hypnosis, or to present substantive material pertaining to these topics. It also treats each topic as continuous with other known psychological phenomena and as an important piece to the puzzle of social psychology. It differs from most previous treatises in that it does not assume that psychedelics, yoga, and hypnosis can bring out unused mental or physical capacities in man, heighten awareness or give rise to enhanced creativity, or produce altered states of consciousness, suspension of conventional reality-orientation, changes in body-image, or changes in perception.

Often, people use nicotine, caffeine, and some level of alcohol in varying combinations at different times of the day in order to optimize their functioning and feelings of well-being, whether at work, in leisure time, or in a social context. However, until now, studies on the effects of this everyday practice have been diverse, widespread, and insufficiently summarized. Recently developed methods to study the effects in more detail have received little attention, especially among a nonscientific readership.
Nicotine, Caffeine and Social Drinking focuses readers' attention on the effects of normal, socially accepted psychoactive substances on cognitive performance and on the brain. Divided into three sections, this book studies each substance individually before examining the effects of their combined usage.

The central problem in the study of addiction is to explain why people repeatedly behave in ways they know are bad for them. For much of the previous century and until the present day, the majority of scientific and medical attempts to solve this problem were couched in terms of involuntary behavior; if people behave in ways they do not want, then this must be because the behavior is beyond their control and outside the realm of choice. An opposing tradition, which finds current support among scientists and scholars as well as members of the general public, is that so-called addictive behavior reflects an ordinary choice just like any other and that the concept of addiction is a myth. The editors and authors of this book tend to take neither view. There has been an increasing recognition in recent literature on addiction that restricting possible conceptions of it to either of these extreme positions is unhelpful and is retarding progress on understanding the nature of addiction and what could be done about it. This book contains a range of views from philosophy, neuroscience, psychiatry, psychology and the law on what exactly this middle ground between free choice and no choice consists of and what its implications are for theory, practice and policy on addiction. The result amounts to a profound change in our thinking on addiction and how its devastating consequences can be ameliorated. Addiction and Choice is a thought provoking new volume for all those with an interest in this global issue.

Inspiring teachings centered on navigating our world's collective challenges with indigenous wisdom and the power of psychedelics * With contributions from Christopher Bache, Zoe Helene, Dennis McKenna, Martina Hoffmann, The Dank Duchess, Jamie Wheal, Grandmother Maria Alice, and others * Explores the immense healing intelligence of nature, the wisdom of ancient Indigenous prophecies and shamanic practices, the importance of the Divine Feminine for environmental regeneration, and the crucial role of psychedelic and entheogenic plants in initiating transformations of consciousness Exploring the way forward for humanity in the face of unprecedented crisis, more than 25 contributors show how the wisdom of Indigenous peoples and the power of psychedelics can help us enact the radical shift in consciousness necessary to navigate the collapse of the old world order and the birth of a new consciousness. We hear from psychedelic visionaries Christopher Bache, Zoe Helene, Wade Davis, Chris Kilham, Laurel Sugden, and others on the promise of psychedelic medicines for spiritual and healing work. We learn about Indigenous stories to support our transformation from Native American leader Solana Booth, ancestral memory from Grandmother Maria Alice Campos Freire, cannabis's role in world building from Minelli Eustacio-Costa, the ritual roots of talking plants from Michael Stuart Ani, and alchemy across the arc of time from shaman Ya'Acov Darling Khan. We also hear from cannabis grower The Dank Duchess; Tyson Yunkaporta, Australian Aboriginal artist and scholar; visionary artist Martina Hoffmann; activist Duane Elgin; Kohenet Rachel Kann, ordained Jewish priestess and ceremonialist; and several other wise leaders for our time. Throughout these profound essays we are reminded of the immense healing intelligence of our plant allies, of the wisdom of shamanic practices, of the importance of the Divine Feminine for environmental regeneration, and of the crucial role of entheogenic plants in initiating transformations of consciousness and healing our world's collective disconnection from Spirit.

In Ten Trips neuropsychologist Andy Mitchell takes ten different psychedelic drugs in ten different settings, puncturing the hype while providing the fullest picture yet of their limitlessly fascinating possibilities. Once demonised and still largely illegal, psychedelic drugs are now officially a 'breakthrough therapy', used to treat depression, trauma and addiction and to enhance well-being. But as neuropsychologist Andy Mitchell shows in this deeply serious yet wildly entertaining investigation, this approach misses what is so strange and valuable about them: the psychedelic experience itself. In Ten Trips he takes ten different compounds, some famous, others obscure, journeying from a neuroimaging lab in London to the Colombian Amazon via Silicon Valley and his friend's basement kitchen. His encounters with scientists and gangsters, venture capitalists and con-men, psychonauts and shamans provide a panoramic view of psychedelics today: their capacity for healing but also trauma, for transcendence and corruption, profundity and hilarity. By removing psychedelics from their indigenous and underground cultures, we risk losing the very things we need to harness them. To make them safe or normal might ultimately destroy what makes them potent. That potential is indeed great, not as an antidote to mental illness - none exists - but as a way of changing our whole perspective on mental health and flourishing. Ten Trips is a dazzling, perception-shifting odyssey that shows how psychedelics can re-enchant us with the world.

Tracing evidence of mind-altering substances across a diverse range of ancient cultures, this collection explores how and why past civilizations harvested, manufactured, and consumed drugs. Case studies examine the use of stimulants, narcotics, and depressants by hunter-gatherers who roamed Africa and Eurasia, prehistoric communities in North and South America, and Maya kings and queens. Offering perspectives from many different fields of study, contributors illustrate the wide variety of sources and techniques that can provide information about materials that are often invisible to archaeologists. They use advanced biomolecular procedures to identity alkaloids and resins on cups, pipes, and other artifacts. They interpret paintings on vases and discuss excavations of breweries and similar sites. Uncovering signs of drugs including ayahuasca, peyote, ephedra, cannabis, tobacco, yaupon, vilca, and maize and molle beer, they explain how psychoactive substances were integral to interpersonal relationships, religious practices, and social cohesion in antiquity.