This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach. Establishing sensitive and specific biomarkers of dynamic redox homeostasis is crucially important in the development of effective antiaging and senolytic interventions. Recent years have seen tremendous advances in the understanding of redox signaling events which highlight the process of aging and age-related pathologies. A major challenge in biological aging research is developing reliable biomarkers to determine the consequences of disrupted redox signaling networks long before the clinical diagnosis of age-related diseases is made. Therefore, we have chosen to concentrate on aging-induced aberrant redox signaling networks, their biomarkers, and pathological consequences in this book. Although oxidation is a natural metabolic process, the imbalance in the level of oxidants and antioxidants causes oxidative stress and eventually leads to inflammatory conditions, diabetes, neurodegenerative diseases, and cancer. Novel redox-sensitive biomarkers for the evaluation of aging-induced proteinopathies such as amyloid ss and tau proteins in Alzheimer's disease, -synuclein in Parkinson's disease, and islet amyloid polypeptides in type 2 diabetes mellitus recently drew the attention of researchers. Inside this textbook, readers will find comprehensive perspectives on the association between redox homeostasis and the aging process both at the molecular and clinical levels. Due to the inherent relationship between impaired metabolic activities and oxidative stress, the temporal interaction between intermediary metabolism and disturbed redox status can lead to greater susceptibility to aging-induced diseases and disorders, such as cardiovascular diseases, hypertension, and diabetes. This knowledge could be a key to continued research toward improving medication regimens such as in cancer and cardiovascular therapies, and procedural outcomes for patients. This book brings together current research evidence and knowledge on redox signaling and biomarkers in aging in chapters written by leading global experts in this rapidly evolving field. We hope that this textbook is of interest to a wide group of researchers, advanced students, scientifically curious non-specialist readers and clinicians alike.

Explores the mother-daughter relationship in the context of caregiving Across the Unites States, about 34.2 million Americans have provided unpaid care to an adult age 50 or older in the last 12 months. Much of this caregiving is performed by women and often for their mothers or mothers-in-law, relationships that may be warm, fraught, or complicated. Even in the best of circumstances, caregivers can feel burned out, strained, and exhausted, but add to the mix the complicated emotions that come from caring for a loved one and you may have a perfect storm. Here, Jeanne Lord provides valuable emotional support and information for daughter caregivers to mother care-receivers during a stressful and uncertain time. It is unique in that it offers not only personal insights from caregiving daughters, but the perspectives of their mothers, as well. Lord followed the women on their journeys over the course of ten years, so the follow-up interviews give readers an opportunity to fast forward into the future lives of the caregiving daughters to read about their perspectives, and gain insights into new attitudes and ideas for life after caregiving. Through compelling stories and in-depth interviews, the very complex relationships between mothers and daughters in a caregiving situation are explored and revealed in an objective light. Offering comfort and understanding to the reader, the book also offers suggestions, ideas, resources, and support for navigating the care of their loved one.

Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more.

Ageing populations represent a key global challenge for the twenty-first century. Few areas of life will remain untouched by the accompanying changes to cultural, economic and social life. This book interrogates various understandings of ageing, and provides a critical assessment of attitudes and responses to the development of ageing societies, placing these in the context of a variety of historical and sociological debates.Written in a highly accessible style, this book examines a range of topics, including demographic change across high- and low-income countries, theories of social ageing, changing definitions of 'age', retirement trends, family and intergenerational relations, poverty and inequality, and health and social care in later life. The book also considers the key steps necessary in preparing for the social transformation which population ageing will bring."Ageing" provides a fresh and original approach to a topic of central concern to students and scholars working in sociology, social policy and wider social science disciplines and the humanities.

The book provides an interesting analysis of the time-use data to examine the extent to which active ageing is occurring in India. It also synthesizes data from the National Sample Survey Office All India Survey and another survey undertaken in Kolkata, Bhubaneswar, and Ranchi (capital cities of East Indian states) to examine the role of the aged in the Indian Society. Nearly all countries in the world are experiencing an important issue of ageing. India faces its own set of challenges with its aging population due to the absence of a social security system-the shifting family dynamics questions the contribution of the elderly to the family in every aspect. Econometric models have been used in the book to study gender differences and variations across socio-economic conditions, correlating them to the contribution of the aged to their families and the extent of active ageing. The book broadens the understanding on the aged and facilitates their integration in the society so that they can age more actively. Active Ageing and Labour Market Engagement offers an analytical perspective to professionals, researchers, and policy makers interested in gerontology.

This book provides a comprehensive view of the quality of life of older people from culturally and linguistically diverse (CALD) backgrounds living in Australia. The book is unique and significant because the descriptions and arguments presented are based on the lived experience and hence provide deep insights into the complexity and dynamics of CALD older migrants. Key areas of exploration include social connectedness and inclusion, post-retirement economic activities, living arrangement and housing choice, practice of care, intergenerational exchange, and life satisfaction. A focus is placed on the diversity of ageing experience. Pathways of ageing are one of the key factors in investigating inter and intra-ethnic commonalities and disparities. The policy and research implications presented will appeal to policy makers, practitioners and researchers.

Handbook of Aging and the Social Sciences, Ninth Edition, provides a comprehensive synthesis of the latest research findings in the science of aging. The complexities of population dynamics, cohort succession and policy changes modify the world and its inhabitants in ways that must be vigilantly monitored. Completely revised, this edition not only includes the foundational, classic themes of aging research, but also a rich array of emerging topics and perspectives that advance the field in exciting ways. New topics include families, immigration, social factors and cognition, caregiving, neighborhoods and built environments, natural disasters, religion and health, and sexual behavior, among others. This book will serve as a useful resource and an inspiration to those searching for ways to contribute to the aging enterprise.

This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1959.

Focusing on contemporary ideas about how aged care is provided, this book poses the question: How can people who are aged and frail live out the final phase of their lives with dignity? In seeking answers, the author examines what it means to be 'at home' in residential care in a novel and compassionate way. In an ethnographic study of how elderly residents can be given the right care, this book provides a new route into the bodily realities of ageing. It is a vital contribution to the search for alternative approaches to aged care provision.

Over the course of more than two decades and five previous editions, The American Psychiatric Association Publishing Textbook of Geriatric Psychiatry has established itself as a foundational resource in the field. This new edition retains the multidisciplinary and developmental perspectives of its predecessors, drawing on the knowledge not only of psychiatrists but also of relevant biomedical and behavioral experts in order to present the most comprehensive approach to patient care. It has been extensively updated to reflect the latest scientific advances and clinical developments in the field. Not only will readers find the most up-to-date information on phenomenology, diagnosis, and assessment of late-life mental disorders, they will also access the latest research on psychotherapeutic, psychopharmacological, and other somatic treatments. A dedicated chapter delves into the role of technology-including digital phenotyping, wearables, digital and Web-based neurocognitive testing, and more-in aiding the geriatric mental health workforce and improving both access to care and ongoing support. Throughout the book, several sections also candidly examine the impact of COVID-19, and its attendant social isolation, on older adult mental health and the evolution of treatment approaches, revealing insights learned about telepsychiatry and care in nursing homes during the pandemic. Chapters on the legal and ethical factors in the psychiatric care of older adults close out the book, the most exhaustive on the topic. Extensively researched and with key points for ease of reference, this edition will equip both the scholar and the clinician with the current state of scientific understanding as well as the practical skills and knowledge base required for dealing with mental disorders in late life.

This book pioneers evidence-based research on healthy aging through the application of self determination theory (SDT). Its uniqueness is located in the fact that to date, no other work has applied SDT to the empirical study of aging populations. The authors focus on how SDT drives healthy, successful and active aging, and note that the motivation factors underpinning healthy aging are often neglected, or altogether absent, in the existing literature. This edited volume is particularly timely given the expanding aging crisis in many North American, European and Asian contexts. The collection of chapters meets this challenge head-on in comparing these contexts vis-a-vis a broad international scope, and subsequent discussions on important specialty issues in aging, such as hearing and memory loss. The work offers global perspectives on aging, autonomy and associated life challenges, as well as factors relating to the sustainability of healthy aging in terms of physical and mental well-being. This book will be highly relevant to researchers in the SDT community, as well as specialists in aging and gerontology. It will also be of interest to lifespan psychologists and developmental psychologists.

Families have become an increasingly important source of support for the elderly, and gerontologists are directing more and more attention to older adults and their families. This bibliography reviews the most significant works on families and aging published within the past ten years. Jean Coyle has selected and annotated nearly 800 books, articles, films, dissertations, and government documents. The detailed annotations summarize and evaluate the significance and usefulness of each item, and the comprehensive author and subject indexes make this volume a valuable reference tool. A thoughtful introduction surveys the most noteworthy research on families and aging done in the last decade. This is followed by eleven chapters, that address such topics as widowhood, intergenerational relationships, family caregiving, and the role of older adults in ethnic and minority families. Gerontologists, social workers, and all those interested in families and aging will find this guide an indispensable source of information.

The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases.

An in-depth and wide-ranging approach to the study of older adults in society Taking a holistic approach to the study of aging, this volume uses biological, archaeological, medical, and cultural perspectives to explore how older adults have functioned in societies around the globe and throughout human history. As the world's population over 65 years of age continues to increase, this wide-ranging approach fills a growing need for both academics and service professionals in gerontology, geriatrics, and related fields. Case studies from the United States, Tibet, Turkey, China, Nigeria, and Mexico provide examples of the ways age-related changes are influenced by environmental, genetic, sociocultural, and political-economic variables. Taken together, they help explain how the experience of aging varies across time and space. These contributions from noted anthropological scholars examine evolutionary and biological understandings of human aging, the roles of elders in various societies, issues of gender and ageism, and the role of chronic illness and "successful aging" among older adults. This volume highlights how an anthropology of aging can illustrate how older adults adapt to shifting life circumstances and environments, including changes to the ways in which individuals and families care for them. The research in Anthropological Perspectives on Aging can also help researchers, students, and practitioners reach across disciplines to address age discrimination and help improve health outcomes throughout the life course.

Evidence-Informed Approaches for Managing Dementia Transitions provides evidence-informed approaches and future directions for supporting a higher quality of life for people living with dementia. Through a person-centered lens, this book equips care providers to better help people living with dementia align their expectations and hopes with the trajectories they can expect in their journey. It highlights the various transitions that those with dementia will experience and describes best practices for optimal adjustment to each. Topics covered include problem identification, driving cessation, loss of financial autonomy, acute hospital admission, moving to assisted living residences and long term care homes, and palliative and end of life care. This is a must have reference for researchers, clinicians, and mental health professionals (psychologists, counsellors, social workers, mental health nurses) as well as policy makers and other health and social care providers working with individuals with dementia.

This work is based upon a research study whose purpose was to collect new information about the special benefits and drawbacks of formal organizations' efforts at social network building for older women. In it, a two-tiered investigation was carried out: a national review of a select group of model self-help support programmes for older women throughout the United States; and an in-depth community case study of a nationally recognized model program of self-help support groups, leadership training, networking and community outreach/education for older women. It provides the research-oriented reader with scientific evidence to assess the relative efficacy of self-help group programming.

This essential volume explores the vital role of communication in the aging process and how this varies for different social groups and cultural communities. It reveals how communication can empower people in the process of aging, and that how we communicate about age is critically important to - and is at the heart of - aging successfully. Giles et al. confront the uncertainty and negativity surrounding "aging" - a process with which we all have to cope - by expertly placing communication at the core of the process. They address the need to avoid negative language, discuss the lifespan as an evolving adventure, and introduce a new theory of successful aging - the communication ecology model of successful aging (CEMSA). They explore the research on key topics including: age stereotypes, age identities, and messages of ageism; the role of culture, gender, ethnicity, and being a member of marginalized groups; the ingredients of intergenerational communication; depiction of aging and youth in the media; and how and why talk about death and dying can be instrumental in promoting control over life's demands. Communication for Successful Aging is essential reading for graduate students of psychology, human development, gerontology, and communication, scholars in the social sciences, and all of us concerned with this complex academic and highly personal topic.

World-wide migration has an unsettling effect on social structures, especially on aging populations and eldercare. This volume investigates how taken-for-granted roles are challenged, intergenerational relationships transformed, economic ties recalibrated, technological innovations utilized, and spiritual relations pursued and desired, and asks what it means to care at a distance and to age abroad. What it does show is that trans-nationalization of care produces unprecedented convergences of people, objects and spaces that challenge our assumptions about the who, how, and where of care.

Adverse Childhood Experiences: Using Evidence to Advance Research, Practice, Policy, and Prevention defines ACEs, provides a summary of the past 20 years of ACEs research, as well as provides guidance for the future directions for the field. It includes a review of the original ACEs Study, definitions of ACEs, and how ACEs are typically assessed. Other content includes a review of how ACEs are related to mental and physical health outcome, the neurodevelopmental mechanisms linking ACEs to psychopathology, sexual violence and sexual health outcomes, and violence across the lifespan. Important and contemporary issues in the field, like reconsidering how ACEs should be defined and assessed, the appropriateness of routine ACEs screening, thinking about ACEs from a public health and global perspective, strategies for preventing ACEs, understanding ACEs and trauma-informed care and resilience, and the importance of safe stable and nurturing environments for children are discussed. Adverse Childhood Experiences is a useful evidence-based resource for professionals working with children and families, including physicians, nurses, social workers, psychologists, lawyers, judges, as well as public health leaders, policy makers, and government delegates.

Presents model programs used to redesign jobs, create opportunities for part-time work, and keep workers age fifty and over productively on the job. Provides a career planning model for assessing the interests and skills of older employees and facilitating successful career changes.E

Work Across the Lifespan coalesces theoretical and empirical perspectives on aging and work. This volume examines a collection of human development theories that explain trajectories of change, including patterns of growth, maintenance, and decline across the adult lifespan. At its core, the lifespan perspective assumes a focus on aging as a continuous process of intraindividual change and goal-based self-regulation. In this text, the lifespan perspective serves as a lens for examining the complex relationship between aging and work. Integrating research from the fields of developmental psychology as well as industrial, work, and organizational psychology, this authoritative reference brings together the collective thinking of researchers who study work, careers, organizations, and aging.

"In society at large, lives have been drastically altered over this century—as a consequence of increased longevity, advances in science and education, the gender revolution, improvements in public health, and other historical trends and events—but numerous inflexible social structures, roles, and norms have lagged behind. There is a mismatch or imbalance between the transformation of the aging process from birth to death and the role opportunities or places in the social structure that could foster and reward people at the various stages of their lives. While the twentieth century has experienced a revolution in human development and aging, there has been no comparable revolution in the role structures of society to keep pace with the changes in the ways people grow up and grow old. The lag involves not only institutional and organizational arrangements, but also the many aspects of culture that, in addition to being internalized by people, are built into role expectations and societal mores and laws. For the future, then, structural changes will be needed if people are to find opportunities to spread leisure and work, as well as education, more evenly over the life course, and to make room for family affairs." —from Age and Structural Lag