Liver Transplantation: Challenging Controversies and Topics grew out of a need I perceived within the fields of transplant hepatology and liver transplantation. Liver transplantation has rightly gained recognition as an established therapy for end-stage liver disease. Few would argue that liver transplantation is one of the few truly lifesaving and life-altering treatments within medicine and surgery. Not many realize that 20 years passed from the time of the first human liver transplantation in 1963 to its acceptance as therapy by the 1983 NIH Consensus Conference on Liver Transplantation. In 2008, 25 years will have passed since the 1983 NIH conference-a mere 25 years for a field that has provided patients hope, doctors options, and to some the "gift of life. " Many issues in liver transplantation involve indications, patient selection, and outcomes after transplantation-these are standard topics, covered by textbooks of hepatology and transplantation. In contrast, the field of liver tra- plantation is young, evolving, dynamic, and issues and decisions are often controversial. Thus, Dr. Trotter and I, as well as our colleagues at the University of Colorado, felt that a text with a different focus was required, one that highlighted controversy and challenged dogma. Out of this perceived need emerged Liver Transplantation: Challenging Controversies and Topics. To meet the transplant community's need for emerging information about liver transplantation, Dr. Larry Chan, Dr. Igal Kam, and I initiated the Controversies in Transplantation Conference.

This volume builds on the success of the first edition of Imaging Pelvic Floor Disorders and is aimed at those practitioners with an interest in the imaging, diagnosis and treatment of pelvic floor dysfunction. Concise textual information from acknowledged experts is complemented by high-quality diagrams and images to provide a thorough update of this rapidly evolving field. Introductory chapters fully elucidate the anatomical basis underlying disorders of the pelvic floor. State of the art imaging techniques and their application in pelvic floor dysfunction are then discussed in detail. Additions since the first edition include consideration of the effect of aging and new chapters on perineal ultrasound, functional MRI and MRI of the levator muscles. The closing sections of the book describe the modern clinical management of pelvic floor dysfunction, including prolapse, urinary and faecal incontinence and constipation, with specific emphasis on the integration of diagnostic and treatment algorithms. Written for: Practitioners and clinicians in the fields radiology, urology, proctology/colorectal surgery, gynecology, gastroenterology

Incisional hernia surgery has witnessed important advances over recent years, not only as far as the pathophysiological and etiopathogenetic aspects are concerned, but also from a technical point of view. This book provides an update on incisional hernia surgical techniques. It includes chapters on synthetic prostheses, biomaterials and robotics. Surgeons, surgical residents, and medical students will find the information in this volume very useful in their daily practice.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

This book is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc. are based on the sensitivity and specificity of the respective methods. Special focus is given to the indication and contraindication to surgical techniques. The book contains specific treatment modality and results for the first time after long-term outcome evaluation. There is detailed description of diagnosis and treatment, and the book is abundantly illustrated with approximately 300 color illustrations.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Laparoscopic Colorectal Surgery, Second Edition is fully revised and updated and reflects an authoritative, team-oriented approach to the latest state-of-the-art laparoscopic colorectal procedures and surgical techniques. Written by pioneers in the field, this text will supply surgeons with all the information necessary to accomplish advanced laparoscopic procedures. Comprehensive discussions of positioning, instrumentation, cannulas, surgical techniques, special considerations, and considerations in cancer surgery are featured for a wide variety of major operative procedures.

This new Second Edition includes updated information on laparoscopic colorectal procedures, including hand-assisted laparoscopic procedures and new chapters on the physiology of pneumoperitoneum, laparoscopic anatomy of the colon and rectum, and evidence-based discussion of outcomes. The text is complemented by over 200 line drawings created exclusively for the textbook.

Hepatobiliary and Upper GI Surgery reflects the overwhelming need for such a book as this specialisation proceeds apace. The book covers all the foregut except the liver, bile duct and pancreas, looking at the diverse anatomy and physiology, the functions and the disease processes. The book reflects a significant change in the management of certain conditions, as our understanding of disease has improved. Technical developments have moved surgery forward; minimally invasive surgery being the treatment of choice for most upper GI operations for benign disease. With cancers of the upper GI tract being common, and with our understanding more of the genetic profile of tumours, we have identified premalignant lesions and cancer surgery is now targeted to allow stage-appropriate therapies. This book gives a current and concise summary of all key topics within the specialty and concentrates on recent developments. Hepatobiliary and Upper GI Surgery brings together an international group of contributors, all experts in their field, to provide a text for specialists and trainees.

This book is a valuable addition to the extensive literature on inguinal hernias, a topic of great interest for all general surgeons. It describes the most up-to-date prosthetic open techniques in the treatment of inguinal hernias, including onlay and inlay procedures. Starting with the Lichtenstein technique, which allowed for the successful and widespread use of the prosthesis technique, the most widely used surgical procedures are described by leading experts in the field. Special attention has been paid to the illustrations and photographs. This book is a useful resource for medical and surgery students, general surgeons, and all those interested in the area of surgery of hernias.

Therapeutic Laparoscopy for Digestive Disease is intended to give the practicing surgeon or trainee an in-depth analysis of the technical aspects of the most commonly performed laparoscopic procedures, their indications, contraindications, and complications. Included are strategies to prevent complications as well as ways to handle them once they occur. Heavily illustrated, the book breaks new ground in visualizing operative procedures and problems. Seven sections, comprising the core curriculum of accepted procedures in laparoscopic surgery, present gallbladder disease, common bile duct exploration, hernia, colon diseases, anti-reflux procedures, acute abdomen and the role of diagnostic laparoscopy, and emerging procedures on the spleen and adrenals. Recognized leaders in the field tackle each section, emphasizing what to do when and how to solve acute situations. The book also features a patient information component for each section, providing the necessary background on the procedure, post-operative period, and recovery. These pages are perforated for inclusion in a binder in the patient office as well as for photocopying as patient take-home instructions. Therapeutic Laparoscopy for Digestive Disease is a practical, must-have resource for the general surgeon, imparting the clinical insight needed for successful performance of the core miminally invasive procedures as well as a source of useful patient information for the office practice.

Few clinical disciplines have been transformed so dramatically by advancements in science and technology as gastrointestinal surgery. To begin with, modern ph- macology has virtually eliminated some kinds of surgery altogether. If one were to take a peek at a typical operating room schedule in a busy hospital of the 1960s, gastrectomies of one kind or another would have constituted a large block of the major surgeries. The advent of effective H2-histamine receptor antagonists and, more + + recently, the H, K -ATPase (proton pump) inhibitors led to a precipitous decline in those procedures such that they are rarely performed today. Exciting new approaches to treating inflammatory bowel diseases and their complications-such as fistulas- with anticytokine therapy may one day have a similarly profound effect on surgery for this condition as well. Beyond pharmaceutics, advances in imaging techniques have greatly facilitated the identification and characterization of pathology in the gastrointestinal tract in a way that would have been unimaginable only a few years ago. Just to visualize the pancreas in some way was a horrendous task until abdominal ultrasound, magnetic resonance imaging, or computer tomography made it simple. The fact that the gut is a hollow organ that can be accessed through the mouth, anus, or even through the wall of the abdomen has been fully exploited with fiberoptic endoscopes that can bend around corners with ease and permit surgery to be conducted through them.

Advances in Abdominal Surgery 2002 contains papers from a group of Italian academic surgeons who contribute to a national research program entitled Progress in Abdominal Surgery'. The research is supported by the Italian Ministry of the University. The primary objective of the group is to combine experimental and clinical approaches in the study of several surgical abdominal diseases. The authors of the individual chapters were requested to present an update in their own fields of research. This volume summarizes several important updates in abdominal surgery and pathophysiology. The contributions are grouped into six sections, namely Surgical Infection, Hepatobiliary and Pancreatic and Splenic Surgery, Colorectal Surgery, Fecal Incontinence, Minimally-Invasive Surgery, and Transplantation.

Abdominal organ transplantation, specifically liver, kidney and pancreatic transplantation, has experienced a tremendous growth over the last two decades. With this growth comes a need for a general, standardized introduction for those healthcare professionals involved with this branch of medicine. This manual is a readily-available, concise reference for the professional involved in the field of abdominal organ transplantation as well as the lay person.

The Practical Manual of Abdominal Organ Transplantation covers the latest developments in organ procurement and transplantation as well as newer approaches to the organ shortage and the increasing use of liver donation. This practical manual serves as an invaluable tool for those in the medical profession, whether a student, resident or practitioner, working with abdominal organ transplantation and its effects on their patients.

This manual includes concise and directed topics covering:

- end-stage abdominal organ disease;

Primary and incisional ventral hernias are common conditions often encountered in surgical practice. Because of the frequency of this problem it has come to be managed by surgeons in general, regardless of the type of hospital or the conditions dealt with in their daily practice. Laparoscopic surgery has demonstrated to have an important role among the different technique described to repair ventral hernia with less recurrent rate, less morbidity and less overall cost than open conventional repair, with all the advange of the laparoscopic approach. As a result the indications for this surgical technique are currently being debated since the advantages are evident and progressive implementation is ensured. Now is the time to analyze the usefulness, results, technical variants, anatomic, physiologic and scientific basis and implications involved in implementation of laparoscopy as the technique of choice.

This book is serving the surgical trainee and the experienced transplant surgeon as a compendium of the various topics in split liver grafting. It is comprised of articles by faculty members of the first International Course on Split Liver Transplantation. Covering the main aspects of Split Liver Transplantation, this excellent volume helps livertransplant-surgeons select the best technique and getting aware of pitfalls. Detailed instructions on the different procedures are round off by an overview on technical development, status quo as well as the experience to date.

With remarkable progress being reported in living donor liver transplants and small bowel transplantation, the 9th Keio International Symposium for Life Sciences and Medicine was auspiciously timed. Titled "Current Issues in Liver/Small Bowel Transplantation," the Tokyo symposium brought together researchers from Japan and other parts of the world. This volume is a compilation of papers from the symposium, organized into five key areas of interest to medical professionals: Technical aspects and physiological problems in split/living donor liver transplantation; Viral hepatitis and liver transplantation; Current status and future prospects in small bowel transplantation; Liver transplantation for malignant hepatic tumors; and Novel strategies in immunosuppression. Containing the most up-to-date information on these vital issues, the book is an essential resource for all researchers and practitioners concerned with liver and small bowel transplantation.

"When a thing ceases to be a subject of controversy, it ceases to be a subject of interest. " WILLIAM HAZLITT (1778-1830) This is the fourth volume in a series which we started in 1997. In 1976, Varco and Delaney edited a "surgical bestseller" entitled Controversy in Surgery. This was fol lowed by a second volume in 1985. The immense success of these books among both surgical trainees and experienced surgeons, and their wide international ap peal, supported the editors' notion that a view of controversy is integral to teach ing. However, despite major advances in surgical science and practice, no other similar publication has since been put together with the objective of addressing major controversies in surgery. The aim of this series is to address such deficiency by covering the most crucial current controversies in general, vascular and trauma surgery. Since almost everything is controversial in surgery, we will be able to tackle different issues almost each year. The editors have selected a nationally/internationally recognized authority for each topic. Most books available today are either "North American: ' "British-Com monwealth" or "British-European: ' contributing to the constant transatlantic rival ry. Our series specifically aims to bridge this "culture gap" and includes North American, British, European, and other authors while maintaining a cohesive structure. This will hopefully also broaden the appeal of such a book across both sides of the Atlantic and beyond."

General surgery consists ofa main corpus of propaedeutic elements and clinical problems, which has been modified over the years by the separate development of numerous sub-specialistic branches. Although a common basis on the physiopathology of surgical trauma and post operative complications persists, as a result of general knowledge of surgical diseases, there is no doubt that in the spheres of doctrine and application, both research and clinical medicine have distinguished themselves autonomously in many surgical fields (orthopedics, neurosurgery, cardiovascular surgery, thoracic surgery, urology, etc.). It is therefore difficult to define the present configuration ofgeneral surgery, but without question abdominal surgery occupies a position of pre-eminent importance within the general framework. We are dealing, in fact, with pathological pictures which occur in a section ofthe body ofvast proportions, in which structures, organs, and morphologically complex spaces are arranged to carry out important functions. They are, therefore, subject to considerably complex pathological alterations, such as to establish an interesting field of diagnostic discussion and an exciting training-ground for surgical activity. It can be affirmed that the diagnosis and cures ofabdominal surgical diseases constitute a test ofthe surgeon's experience. Diagnosis is often entrusted to a differential process, the results ofwhich may be confirmed today by complementary diagnostics. This, however, must be guided by predominating clinical considerations, the exaggerated use of diagnostic techniques, detached from clinical examination, being the cause of very serious errors, which can mislead decision making and human contact, which is the basis ofcorrect medical practice.

This is a user-friendly reference on all aspects of office-based anorectal surgery for general surgeons and surgeons in training. Well-illustrated, this practical manual shows step-by-step procedures for commonly performed anorectal procedures. The book includes ancillary considerations of ambulatory surgery with timely chapters on set-up of the facility, anesthetic considerations, selection of patients, pre-op and post-op management, nursing aspects, and coding and billing.

This comprehensive, illustrated guide presents representative general surgery, including gastrointestinal tract, hepatobiliary and inguinal hernia. Surgery is generally based on the microanatomy; however, in practice surgery involves more dynamic and floating anatomy. In the last decade, the methods have been constantly improved, shedding new light on classical anatomical science. Laparoscopic is one such methodology. All illustrations presented in this book have been drawn by the author - a pioneering surgeon - and show real-world procedures. All the methods introduced are practical and have been refined based on the precise clinical and embryological anatomy. This unique book offers readers essential insights into efficient and high-integrity surgeries in abdominal region. As such, it is a valuable resource for all gastrointestinal surgeons.

Chronic Pelvic Pain: Evaluation and Management presents a clinically oriented, multi-disciplinary approach to the diagnosis, treatment, and management of chronic pelvic pain in women -- one of the most common problems encountered in the practice setting. The editors present this challenging and often vexing subject in a practical, user-friendly, highly illustrated text, including chapters on: physiology of pain; pain associated with endometriosis; pain associated with fibroids; surgical management; the role of office based surgery; the role of the psychiatrist in pain management; pelvic pain of urinary origin; pelvic pain of gastrointestinal origin. Designed to be incorporated into the every day practice, this book is a must for all clinicians in obstetrics-gynecology as well as for any physician involved in the health care of women.

Protocols for Enhancing Function of Fetal Islets in vitro and following Transplantation (A. Hayek, G.M. Beattie). Expression of Two Nonallelic Reg Genes in the Developing Human Pancreas: Effects in vitro of Nicotinamide and Maternal Growth Factors (B. Formby et al.). Preparation of Fetal Islets for Transplantation: Importance of Growth Factors (D.A. Hullet et al.). Studies of Fetal Porcine Isletlike Cell Clusters-A Tissue Source for Xenotransplantation in Insulindependent Diabetes Mellitus? (S. Sandler). Basic Biology of Pig Fetal Pancreas and Its Use as an Allograft (B.E. Tuch et al.). Combined Transplantation of Adult and Fetal Islets for Improvement of Graft Function (Y. Mullen). Studies on Pretreatment of Human Fetal Islet in Vitro and Clinical Islet Transplantation in China (Y.F. Hu et al.). The Use of Human Fetal Islet Tissue for Adjunctive Treatment in Insulindependent Diabetic Patients: The Case for 'Partial Success' (L. JovanovicPeterson et al.). Longterm Studies with Cultured and Cryopreserved Human Fetal Islets for Islet Transplantation in Hungary (G. Farkas). Fetal Islet Transplantation and Pregnancy (C.M. Peterson et al.). Encapsulated Human Islet Transplant Trials in Type I Diabetic Patients (P. SoonShiong). 4 additional articles. Index.

Biliary tract complications are still the major cause of morbidity following orthotopic liver transplantation. This book deals systematically with the large variety of possible cholangiographic changes. The figures are the results of a review of cholangiograms from more than 280 patients who underwent orthotopic liver transplantation. The etiology, clinical aspects, and treatment of these complications are reviewed on the basis of the authors' experience in radiology, endoscopy, and transplant surgery.

This volume is a compendium of the lectures, presentations, and workshops of the International Congress entitled "Facing the Pancreatic Dilemma" and of the 17th Meeting of the Italian Association for the Study of the Pancreas, held in Verona on 16 -19 June 1993. Pancreatology is still a relatively young science. Many pathophysiological aspects of pancreatic disease are as yet obscure, and a fair number of the etio pathogenetic mechanisms adduced are no more than hypothetical. We have therefore chosen to compare and contrast in a single volume the various hypo theses and interpretations put forward by leading experts in the field. In view of the swift evolution of this branch of medical science, it is sound policy to bear in mind that yesterday's heresies have become today's orthodoxy, and that todays's heresies may well turn out to be accepted orthodoxy in a not too distant future. The various "pancreatic dilemmas" are addressed systematically in these pages, and we believe that the book will prove an invaluable tool for the special ist and for any physician dealing with pancreatic disease. The book also represents a tribute by the Verona School of Pancreatology to the memory of Prof. L. A. Scuro, founder of the School and one of the outstanding Italian pioneers of pancreatology."

The present book intends to provide a comprehensive guide to the field of robotic bariatric surgery. It covers all the stages and procedures needed to fulfill credentialing for performing robotic surgery. Also, robotic surgery is presented as an institutional program, and we describe how to establish a robotic program in a hospital environment. The currently accepted and most common procedures - sleeve gastrectomy, gastric bypass and duodenal switch - are described in detail, with a step-by-step description of the techniques, followed by a wealth of photos and videos for each case. Special attention is given to the employment of robotic bariatric surgery in exceptional conditions, such as in super-obese patients, reoperations and revisional procedures. Critical issues, for the success of the robotic surgical interventions, such as anesthesia, are also addressed. Finally, the outcomes of robotic bariatric surgery are described, including long-term weight loss, improvement and resolution of comorbidities and improvement in quality of life. Bariatric Robotic Surgery is the first book specially devoted to this modality of surgical intervention. It is a fundamental tool for surgeons, residents and fellows who want to start a robotic bariatric surgery program. The book also helps experienced robotic surgeons to keep up to date with the various available robotic surgical techniques.