With a particular emphasis on tumor dormancy in breast, lung, prostate, and liver cancers, as well as in melanoma, this first volume of a new Springer series focuses on the interrelationship between biological processes of aging and tumors -- both dormant and quiescent. With detail supplied by numerous international researchers at the forefront of cancer research, the book examines a host of differing aspects of the topic. Featured contributions analyze the role of the quiescent state in regulating hematopoietic and muscle stem cells. They also explore the mediation, by the kinase, in the reversible quiescent state of a subset of ovarian, pancreatic, and colon cancers. The book includes key research on the molecular mechanisms underlying stress-induced cellular senescence, in addition to those governing the accumulation of reactive oxygen species, and the induction of premature senescence. It also provides information on suppressing cellular senescence in the most common, and most aggressive malignant primary brain tumor in humans, glioblastoma multiforme. With comprehensive and cutting-edge information on therapeutic interventions and on the correct diagnosis of relevant neoplasms, and with numerous color illustrations, this is the most up-to-date assessment of current medical knowledge in this crucial area of medical research.

This book is a collection of mortality abstracts based on recent follow-up studies on the results of health disorders from the abstracts and articles appearing recently in the Journal of Insurance Medicine. The widely different types of investigators who may have repeated need of outcome data (death or morbid event) in a particular disease or risk factor will find this collection invaluable. Such a collection is valuable not only to users in the insurance industry, but to all physicians and health scientists who are interested in prognosis of chronic diseases, in clinical trials, in cost/benefit questions, in clinical decision-making, and similar fields of inquiry.

Obesity has reached epidemic proportions globally and presents a major challenge to policy makers and clinicians alike. Recent research has suggested that obesity has its origins in early life and that early diet can programme a developing fetus and young infant s future susceptibility to obesity. This volume contains recent findings presented at the International Conference on Early Nutrition Programming and Health Outcomes in Later Life: Obesity and Beyond - a satellite meeting of the 15th European Congress on Obesity, held in Budapest in April 2007. Basic scientific research, data from epidemiological studies and clinical trial results were all presented during the programme.

This volume includes articles discussing the evidence for an effect of early nutrition programming on later obesity and cardiovascular risk; the growing evidence for an intergenerational cycle of obesity; the role of maternal leptin in programming appetite; possible cellular mechanisms for altered energy balance, including mitochondrial programming and the effects of regulators of metabolism; and how epigenetic changes might be the fundamental underlying mechanism explaining programming effects. Consumer understanding of the concept of early nutrition programming and the extent to which early nutrition programming is taken into account in infant feeding policies are also discussed.

It has been well documented that the health status of many Aboriginal people remains the poorest in Australia despite many years of research, policies and interventions. The third edition of "Binan Goonj: Bridging Cultures in Aboriginal Health 3e" explores the processes and practices which have created this situation and looks to provide practical strategies to work towards redressing it. Extensively adopted as a teaching text across Australia, Binan Goonj provides coverage of essential Aboriginal health topics in an accessible manner. This edition challenges the reader to examine their own values, the relativity of values and the use of power in society with a writing style that will engage readers from a range of backgrounds. Thoroughly updated and revised the third edition of "Binan Goonj: Bridging Cultures in Aboriginal Health 3e" provides current up-to-date literature addressing the complexity and multidisciplinary topics of Indigenous Health.

There has been a significant increase in the prevalence of certain chronic disorders among children and adolescents. For example, health experts warn of an epidemic of diabetes mellitus due to an increase in the sedentary life style and poor nutrition of children. There are many questions still to be addressed in the study of chronic disorders among children and adolescents.What are the risk factors associated with chronic diseases in these populations?What are the major complications that contribute to disability and increased health care utilization and costs? What impact do chronic diseases have on the psychosocial development? What are the most effective diagnostic, treatment, and rehabilitation strategies? How can patient education and self-management activities be improved to help children and adolescents improve compliance with treatment regimens? How can parents and other family members become more involved in assessment and management? In what ways can peers, schools, religious institutions, and other organizations help children and adolescent scope with their chronic disease? This book addresses these questions by focusing on how eight chronic disorders affect health care utilization, costs, coping, and health outcomes in children and adolescents.Research studies are used to illustrate wide range of topics from the epidemiology of chronic diseases in children and adolescents, health care utilization and costs, to treatment outcomes, disability, and family processes.Case studies from a clinical psychologist's private practice are used to clarify major psychosocial issues underlying chronic diseases in these populations. Chapter One analyzes the epidemiology of eight chronic conditions in children and adolescents. Data on the prevalence of diseases and associated risk factors are stressed in this chapter. Health care planners can use these analyses to improve primary, secondary, and tertiary prevention through more effective uses of health care resources. Chapter Two examines the latest information on health care utilization and costs for children and adolescents that can point to a more efficient means of reducing the rising health care costs associated with the treatment of chronic diseases.

In the remaining chapters, the eight chronic diseases are evaluated in terms of five major issues. First, the latest trends in complications associated with each chronic condition are explored.Second, the impact of each disease on disability and psychosocial development of children and adolescents are analyzed. Third, recent research findings on diagnosis, treatment, and rehabilitation strategies are discussed. Fourth, new trends in patient education and self-management are presented. Fifth, each chapter will assess the role of family, peers, schools, and other organizations in helping children and adolescents cope with their chronic disorders. Dr. Mark L. Goldstein, a clinical psychologist, reviews the literature and uses composite case studies from his practice to illustrate the impact of these trends on how children and adolescents manage chronic disease.The information in this book will be relevant to a wide range of professionals and students in the fields of pediatrics, medicine, nursing, public health, mental health, social work, education, health administration, health policy, and social sciences."

This volume describes classic and contemporary theory and research in social psychology that sheds light on how people think about health and illness, as well as their willingness to engage in health-relevant behaviors. The Editors have selected papers that serve to illustrate the reciprocal relation between advances in theory and advances in practice.

The first two sections of the volume examine people's mental representations of health and health practices, and how these personal construals and implicit theories are linked to behavior. People can react to new health information in different ways - with acceptance, defensiveness, or downright ignorance. Research that can help us to understand these varied reactions is examined in Section 3. The following sections consider how classic social psychological theories and perspectives can be used to understand behavior relevant to health and illness. These include social influence, social comparison, pluralistic ignorance, social support, cognitive dissonance, message framing, and attribution theory. Finally, several articles consider links between personality characteristics and health, such as those between hostility and heart disease, and confiding traumatic experiences and immune function. The volume also contains a introductory chapter by the editors which provides a discussion of why social and personality psychologists should be interested in health and illness.

Together with overviews for each section, discussion questions, and suggestions for further reading, the volume is an ideal text for advanced undergraduate and graduate courses on health psychology. The volume is also appropriate for courses in related disciplines such as public health, nursing, health education, health communication, and other allied health sciences.

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Public health has, for many years, been concerned with efforts to increase the efficiency of health care delivery, to measure changes in health care resource utilization and associated costs, and to link these changes to different types of interventions. These efforts, as well as collaboration between biopharmaceutical organizations, producers of medical devices, and managed care and public health organizations, have been enhanced by the opportunities created within the fast growing field of outcomes research. This volume presents studies contributing to the enhancement of the outcomes research paradigm by incorporating economic and social interactions within the health care delivery, clinical decision-making and outcomes systems. A multidisciplinary team of scientists in the fields of outcomes research, pharmacoeconomics, public health, health services research, and health economics address such complex problems as: benefits and cost of advancements in genetic technologies; methodologies for constructing health care utilization and cost estimates; and the effect of insurance type on resource utilization and health outcomes. Other studies consider both the types of drugs purchased and the prices paid, pharmaceutical spending and health outcomes, incremental advantages of newer treatments, willingness to pay measurements, disease-specific impacts on human capital and quality of life, and modelling clinical trial results. One of the most important findings in this book is the description of the role of low energy in the symptomatology of depression and its strong relationship with absenteeism, work productivity and social functioning. Another paper documents the disease-specific mortality, case-fatality and annual health care utilization in diabetics and establishes the association of respiratory conditions with elevated mortality among diabetics. The work contains other papers which provide significant results in cardiovascular, infectious, central nervous system disease areas as well as in quality of life and health outcomes measurements.

This is the first book to deal exclusively with the influence and meaning of what media historian Paul Heyer calls our century's first collective nightmare. Using contemporary as well as archival sources, he explores a series of intriguing questions: Why has the TITANIC disaster affected the way we think about ourselves and our technology? How has the media made it into a morality play of mythic dimensions? What impact has that story had on the development of 20th-century communications? This timely and compelling book pays homage to the TITANIC's fateful voyage by attempting to explain not why she struck an iceberg on a cold April night in 1912, but what is surely her greatest enigma: the hold the event still has over us.

Heyer assesses the impact of the TITANIC disaster on the 20th century by exploring the relationship between the event and a variety of media from 1912 to the present. The role of the media in the disaster begins with the TITANIC's distress call. Only a partial success, it resulted in a concerted plea for more wireless regulation. Subsequent newspaper coverage called the sinking the story of the century. The mad scramble for information led to the use of every possible journalistic technique, ethical or otherwise. In his analysis, Heyer puts particular emphasis on the New York Times, which became the paper of record and achieved international prominence for its accurate and sometimes controversial reporting. As soon as press coverage subsided, the TITANIC tragedy resurfaced in literature and film. It has gone on to become one of the most enduring myths in 20th century popular culture. Heyer examines this phenomenon, and shows us how and why, following the discovery of the wreck (1985) and the Challenger disaster (1986), our obsession with the TITANIC has been greater than at any other time since 1912. This is a unique and provocative book that will appeal to readers interested in popular history, media studies, and American studies.

This book introduces novel and groundbreaking theories on social medicine, social medicine therapy and pharmacogelotology. Aimed at improving the global health care system in terms of cost-effectiveness and efficiency, the research included in this book represents a paradigm shift from traditional drugs to social medicine. Tracing the history of social medicine, from Natural Healing Power (NHP), Oriental Medicine's vitalism, to Homeostasis (Natural Healing Strength) and Reciprocity (Social Healing Strength), the book first focuses on laying the theoretical foundations. It then highlights how social medicine can be specialized into various social medicine therapies (i.e., aromatherapy, stone therapy, diet therapy, exercise therapy, light therapy, etc.), just like stem cells. This is followed by arguments that 21st century pharmacy should be a harmonious system where the replacement of traditional drug products (i.e., herbal, chemical, and biological products) with new social medicine takes precedence. To that end, the author focuses on the '4+2 system' with 4 representing diet, body, stress, and facial-image control, and 2 representing the complementary and alternative medical methods of evacuation(-) and filling(+). In the context of pharmacogelotology, the book then goes on to present findings on theories of laughter and laughter therapy practices, which are systematically examined and described in detail. Finally, it calls for the development of social-medicine structures by governments that aim to help local authorities use their resources effectively, and for local governments to establish the long-term planning on social-medicine therapy for healthy ageing.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasises the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

This first-person account by one of the pioneers of HIV/AIDS research chronicles the interaction among the pediatric HIV/AIDS community, regulatory bodies, governments, and activists over more than three decades. After the discovery of AIDS in a handful of infants in 1981, the next fifteen years showed remarkable scientific progress in prevention and treatment, although blood banks, drug companies, and bureaucrats were often slow to act. 1996 was a watershed year when scientific and clinical HIV experts called for treating all HIV-infected individuals with potent triple combinations of antiretroviral drugs that had been proven effective. Aggressive implementation of prevention and treatment in the United States led to marked declines in the number of HIV-related deaths, fewer new infections and hospital visits, and fewer than one hundred infants born infected each year. Inexplicably, the World Health Organization recommended withholding treatment for the majority of HIV-infected individuals in poor countries, and clinical researchers embarked on studies to evaluate inferior treatment approaches even while the pandemic continued to claim the lives of millions of women and children. Why did it take an additional twenty years for international health organizations to recommend the treatment and prevention measures that had had such a profound impact on the pandemic in wealthy countries? The surprising answers are likely to be debated by medical historians and ethicists. At last, in 2015, came a universal call for treating all HIV-infected individuals with triple-combination antiretroviral drugs. But this can only be accomplished if the mistakes of the past are rectified. The book ends with recommendations on how the pediatric HIV/AIDS epidemic can finally be brought to an end.

Increasing health literacy among patients is a difficult task as medical jargon and healthcare directions can be overwhelming and difficult to comprehend. In today's digital world, people are more connected than ever before and have the ability to find healthcare information in a way that was not possible in recent years. Mass media and social media have become particularly influential in conveying health information to the public. With the amount of misinformation being spread, coupled with poor health literacy skills, it is imperative that new strategies and policies are undertaken to ensure that patients and the general public receive accurate information and are appropriately educated in order to provide them with the best possible knowledge and care. The Research Anthology on Improving Health Literacy Through Patient Communication and Mass Media provides an overview of the importance of health literacy and the various means to achieve health literacy for patients using several strategies and elements such as patient communication and mass media. The book covers health awareness challenges that have been faced recently and historically and pushes for better patient-provider communication. The book also examines the use of social media, virtual support groups, and technological tools that aid in the facilitation of health knowledge. Covering a range of key topics such as patient safety, health illiteracy, and eHealth, this anthology is crucial for healthcare professionals, researchers, academicians, students, and those interested in understanding the importance of health literacy and how it connects to media and communication.

This handbook offers a comprehensive review of the research on emotional development. It examines research on individual emotions, including happiness, anger, sadness, fear, and disgust, as well as self-conscious and pro-social emotions. Chapters describe theoretical and biological foundations and address the roles of cognition and context on emotional development. In addition, chapters discuss issues concerning atypical emotional development, such as anxiety, depression, developmental disorders, maltreatment, and deprivation. The handbook concludes with important directions for the future research of emotional development. Topics featured in this handbook include: The physiology and neuroscience of emotions. Perception and expression of emotional faces. Prosocial and moral emotions. The interplay of emotion and cognition. The effects of maltreatment on children's emotional development. Potential emotional problems that result from early deprivation. The Handbook of Emotional Development is an essential resource for researchers, clinicians/professionals, and graduate students in child and school psychology, social work, public health, child and adolescent psychiatry, pediatrics, and related disciplines.

Polluted air and contaminated food and water are major causes of human health deterioration, but public health policy has long struggled to effectively address these concerns. This timely book--written for a wide audience of policy makers, researchers, and general readers--synthesizes what we already know about environmental hazards, identifies the gaps in our knowledge, and provides a roadmap for reducing human exposure to environmental pollution. With contributions from leading experts, Environmental Determinants of Human Health examines numerous pollutants, both inorganic and organic, in the context of their human health impacts. Individual chapters explore exposure pathways, macroeconomic impacts of human health deterioration, technological and non-technological methods for reducing exposures, monetary and non-monetary benefits from exposure reduction, and risk communication and awareness, including citizen participation approaches. This volume is a crucial text for policy makers requiring scientific justification for the development of new environmental regulations, scientists researching public health and environmental contamination, and members of the public interested in human health issues.

This text provides a foundation for the initiation of advocacy efforts and for the evaluation of their success and includes topics such as: specific strategies, grassroots advocacy efforts, formation and development of coalitions, advocacy efforts in legislatures, administrative agencies, court, and the media. It is of interest to public and urban health workers, social workers, community organizers, and legislators.

As a result of arms control efforts over the past 50 years, nuclear material is subject to strict national controls and tough international treaties. But there are still almost no controls, other than a voluntary International Atomic Energy Agency code of conduct, on the sorts of radiological sources used to make radiological dirty bombs. Radiological sources are used all over the world for a wide range of peaceful purposes, including smoke detectors, medical devices, meteorology, mining and thermoelectric generators. There are at least eight million identified radiological sources worldwide. Their small size, portability and high value make them vulnerable to misuse and theft: the IAEA reported 272 cases of illicit trafficking in sealed radioactive sources between 1993 and 2002.

The IAEA estimates that 110 countries worldwide still fail to impose adequate controls. The time is ripe for an international convention and treaty on the safety and security of radiological sources.

This book covers expert discussions designed to enhance cooperation and assistance between NATO and Partner countries in support of International Atomic Energy Agency (IAEA) efforts to secure radioactive sources against the threat of terrorism and also to support the security agenda at the International Radiation Protection Association Congress in Buenos Aires in 2008.

Asia has become the new battle ground for the war against HIV/AIDS. The magnitude of the potential public health problems caused by AIDS in this populous continent may become a catastrophic disaster. A 10% rate of prevalence of HIV-1 in India and China alone would mean more than 200 million people are infected with HIV.
AIDS in Asia is useful as a comprehensive, up-to-date AIDS reference book for public health and medical professionals. This volume provides concrete information on the diagnosis, treatment, care, prevention and impact of AIDS. Part I contains 'Snapshots of HIV/AIDS in Asia.' Countries and regions included in this section are: Thailand, India, China, Japan, Vietnam, Laos, Cambodia, Myanmar, Malaysia, Indonesia, the Philippines, Pakistan, Nepal, Sri Lanka, Hawaii and the Pacific Islands, Hong Kong and Taiwan. Part II addresses the molecular epidemiology of HIV/AIDS. Part III deals with the diagnosis, surveillance and projected scenarios of the AIDS epidemic. Part IV outlines prevention efforts and treatment options. Part V provides an overview of the ongoing collaborative efforts involved in several different nations in the worldwide war against AIDS.
This volume will be invaluable to all the public health professionals and researchers working in this field.

..".the book is a useful addition to the HIV/AIDS literature."

"AIDS in Asia offers a comprehensive, interesting overview of the epidemic there and of general issues that will influence its progression."

-Roger Detels, MD, MS, University of California-Los Angeles

The Journal of the American Medical Association, Book Review, 293:15

This volume creates a multi-disciplinary dialogue about clinician-patient communication. It offers a description of the relevance of culture as a contextual effect that impacts the clinician-patient relationship. Some topics addressed include: oncology care, quality of life issues, supportive survivorship, etc. It is for physicians, nurses, hospice and palliative care professionals and public health professionals.

Applying multimodal textual analysis to the languages and images of online communication forms, Kay Richardson shows, from an applied linguistic perspective, how the Internet is being used for global, interactive communication about public health risks. Detailed case studies of the possible risks posed by SARS, by mobile phones and by the vaccination of babies against childhood diseases are situated within the context of research on computer-mediated communication, as well as within the broader social context of globalization and discourses of risk and trust.

Since it was founded in 1930, the W.K. Kellogg Foundation has helped to develop health initiatives based on the premise that if given the tools, individuals, institutions, and communities will make changes for the better. As a reflection of that philosophy, the Kellogg Foundation funded the Community Partnerships with Health Professions Education initiative to seek new approaches to educating primary care practitioners by linking universities and communities. Building Partnerships is the first book to report on this five-year initiative. Written in accessible language, the book is filled with real-life stories and situations that suggest the scope and variety of the partnerships and the diversity of the people who are creating them. By illuminating the Community Partnerships model, Building Partnerships suggests ways community members, academe, and policy makers at multiple levels can lead educational reform in health professions education.

A growing body of research identifies strong links between children's health, social and educational outcomes; it also notes the reciprocal benefits of access to quality education on individual and family health status. In response to these findings, the World Health Organization developed the concept of the Health-Promoting School (HPS), a living catalyst for healthy lives, and for positive changes that students can take home and into the community. Case Studies in Global School Health Promotion provides readers with a theoretical and research base needed to understand the methods used in communities all over the world to put this captivating concept in place.

Case examples from over two dozen countries (representing urban and rural areas in developing and developed nations) outline the strategies taken to implement HPS programs in individual schools, municipalities, and nations. For each program, case study authors explain the problems they tackled, their motivation and supports to respond creatively; and the barriers they faced. In the cases, authors describe the capacities and infrastructure they created and mechanisms for cooperation; as well as the personnel, financial, and time requirements involved. Case studies were drawn from the following regions:

Case Studies in Global School Health Promotion offers a world of insights, ideas, and guidance to those addressing social determinants of health at this formative stage, including: education and health policy makers; professionals and administrators; and researchers in national governments, universities, local schools, community, non-governmental organizations and civil society. The material provides interesting and useful information to those dedicated to these issues within WHO, FRESH Partners and other United Nations agencies. It is also an instructive text for graduate students in public health, education, allied health professions and social sciences.